HLAタイピング市場:技術(PCR(SSO、SSP、リアルタイム)、シーケンス(NGS、サンガー))、製品(装置、試薬、ソフトウェア)、アプリケーション(キメリズム、抗体スクリーニング)、エンドユーザー(病院、診断ラボ、アカデミア)、地域別-2028年までの世界予測HLA Typing Market by Technology (PCR (SSO, SSP, Real Time), Sequencing (NGS, Sanger)), Product (Instrument, Reagent, Software), Application (Chimerism, Antibody Screening), End User (Hospital, Diagnolab, Academia) & Region - Global Forecast to 2028 HLAタイピング市場は、2022年の14億米ドルから2028年には21億米ドルに達すると予測され、予測期間中のCAGRは6.5%になると予測されています。感染症、移植片拒絶反応、自己免疫疾患、癌の早期診断が可能な臨床診断... もっと見る
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サマリーHLAタイピング市場は、2022年の14億米ドルから2028年には21億米ドルに達すると予測され、予測期間中のCAGRは6.5%になると予測されています。感染症、移植片拒絶反応、自己免疫疾患、癌の早期診断が可能な臨床診断法の必要性と強い需要が、研究活動の高まりを支えています。Journal of Human Genetics(2015年)によると、ヒト白血球抗原(HLA)分子(免疫に関与)の研究は、NGS技術から大きな恩恵を受けている。このように、NGS技術によって完全なHLA配列メカニズムが可能になり、転写、遺伝子発現の制御、エピジェネティクスなどのHLA遺伝子変調の理解が容易になったため、NGSを用いたハイスループットのHLAタイピング法がいくつか開発されました。このため、政府機関や民間企業では、被験者の遺伝子プロファイリングやクロスマッチングを目的とした研究活動を支援する動きが活発化しています。"2022年、分子アッセイ技術分野が市場で最大のシェアを占める" 2022年、he molecular assay technologiesセグメントが最も高いシェアを占めると予測された。同分野の高い市場シェアは、リアルタイムサンプル分析、マルチサンプル研究機能、高い手続き効率、低いターンアラウンドタイムなど、分子アッセイ技術の利益に起因するものである。 「2022年、試薬・消耗品が最大のシェアを占めている。 製品・サービス別に見ると、2022年のHLAタイピング市場では、The consumables & reagentsセグメントが3つの中で最も高いシェアを占めていると報告されています。HLAタイピングにおける試薬・試薬の使用の増加、研究調査における試薬・試薬の受け入れの増加、主要地域における早期かつ効果的な治療計画の移植診断に対する患者の重要性の高まりが、予測期間中のこのセグメントの市場成長を決定すると予測されます。 「北米地域のHLAタイピング市場は、予測期間中に最も高い成長を遂げると予測されています。 北米は、2022年のHLAタイピング市場において45.0%の最大シェアを報告しました。この北米の最高シェアは、開発された診断ツールの採用増加、カナダと米国における慢性疾患の発生率と有病率の上昇、技術開発の進展に起因しています。 一方、APACは今後数年間で大きな成長が見込まれます。APAC地域のHLAタイピング市場は、予測期間中にCAGR 7.5%を記録すると予想されています。これは主に、アジア諸国における病院数の増加や政府の有利な取り組みが理由です。 本レポートで参照した主な参加企業の内訳は以下の通りです: - 企業タイプ別企業タイプ別:Tier 1-40%, Tier 2-30%, Tier 3- 30 - 役職別Cレベル:27%、ディレクターレベル:18%、その他:55 - 地域別北米35.3%、欧州20%、アジア太平洋15%、中南米10%、中近東・アフリカ5 HLAタイピング市場の主要プレーヤーは、Bio-Rad Laboratories, Inc.(米国)、F. Hoffmann-La Roche Ltd. (スイス)、QIAGEN, Inc.(スイス)、QIAGEN N.V.(オランダ)、Thermo Fisher Scientific Inc.(米国)、bioMérieux S.A.(フランス)です。その他、Immucor, Inc.(米国)、Illumina, Inc.(米国)、Luminex Corporation(米国)、CareDx(米国)、Becton, Dickinson and Company(米国)、Hologic(米国)、GenDx(オランダ)、Biofortuna(英国)などがある。 調査対象 本レポートでは、製品・サービス、技術、用途、エンドユーザー、地域に基づいて、HLAタイピングにおける市場を調査します。また、市場成長に影響を与える要因を網羅し、市場における様々な機会と課題を分析し、市場リーダーのための競争環境の詳細を提供します。さらに、ミクロ市場を個々の成長動向に関して分析し、主要5地域(およびこれらの地域のそれぞれの国)に関して、市場セグメントの収益を予測しています。 本レポートを購入する理由 本レポートは、既存企業や新規参入企業、中小企業が市場の動向を把握し、より大きな市場シェアを獲得するために役立つものです。本レポートを購入された企業は、以下の戦略の1つまたは複数を組み合わせて、市場での存在感を高めることができます。 本レポートでは、以下のポイントについて考察しています: - 市場浸透度:市場浸透:マイクロカテーテル市場のトップ企業が提供する製品ポートフォリオに関する包括的な情報。 - 製品開発/イノベーション:マイクロカテーテル市場における今後の動向、研究開発活動、製品発表に関する詳細なインサイトを提供します。 - 市場開発:有利な新興地域に関する包括的な情報を提供します。 - 市場の多様化:新製品、成長地域、マイクロカテーテル市場の最新動向に関する詳細な情報を提供します。 - 競争力のある評価:市場セグメント、成長戦略、収益分析、主要市場プレイヤーの製品に関する詳細な評価。 目次1 INTRODUCTION 271.1 STUDY OBJECTIVES 27 1.2 MARKET DEFINITION 27 1.2.1 INCLUSIONS AND EXCLUSIONS 27 1.3 MARKET SCOPE 28 1.3.1 MARKETS COVERED 28 1.3.2 GEOGRAPHIES COVERED 28 1.3.3 YEARS CONSIDERED 29 1.4 CURRENCY CONSIDERED 29 1.5 STAKEHOLDERS 29 1.6 SUMMARY OF CHANGES 30 2 RESEARCH METHODOLOGY 31 2.1 RESEARCH DATA 31 FIGURE 1 HLA TYPING MARKET: RESEARCH METHODOLOGY 31 2.1.1 SECONDARY DATA 32 2.1.1.1 Key data from secondary sources 32 2.1.2 PRIMARY DATA 33 FIGURE 2 PRIMARY SOURCES 33 2.1.2.1 Key data from primary sources 34 2.1.2.2 Insights from primary experts 35 2.1.2.3 Breakdown of primary interviews 35 FIGURE 3 BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY TYPE, DESIGNATION, AND REGION 36 2.2 MARKET SIZE ESTIMATION 36 FIGURE 4 MARKET SIZE ESTIMATION: REVENUE SHARE ANALYSIS 37 FIGURE 5 TOP-DOWN APPROACH 38 2.3 MARKET BREAKDOWN AND DATA TRIANGULATION 40 FIGURE 6 DATA TRIANGULATION METHODOLOGY 40 2.4 MARKET SHARE ESTIMATION 41 2.5 RESEARCH ASSUMPTIONS 41 2.6 LIMITATIONS 41 2.6.1 METHODOLOGY-RELATED LIMITATIONS 41 2.7 RISK ASSESSMENT 42 TABLE 1 LIMITATIONS AND ASSOCIATED RISKS 42 2.8 HLA TYPING MARKET: RECESSION IMPACT 42 3 EXECUTIVE SUMMARY 43 FIGURE 7 HLA TYPING MARKET, BY TECHNOLOGY, 2023 VS. 2028 (USD MILLION) 43 FIGURE 8 HLA TYPING MARKET, BY PRODUCT & SERVICE, 2023 VS. 2028 (USD MILLION) 44 FIGURE 9 HLA TYPING MARKET, BY END USER, 2023 VS. 2028 (USD MILLION) 44 FIGURE 10 HLA TYPING MARKET, BY APPLICATION, 2023 VS. 2028 (USD MILLION) 45 FIGURE 11 ASIA PACIFIC REGION TO DOMINATE MARKET DURING FORECAST PERIOD 46 4 PREMIUM INSIGHTS 47 4.1 HLA TYPING MARKET OVERVIEW 47 FIGURE 12 INCREASING NUMBER OF ORGAN TRANSPLANTATIONS AND RISING ADOPTION OF DONOR RECIPIENT CROSS-MATCHING TO DRIVE MARKET 47 4.2 HLA TYPING MARKET, BY DIAGNOSTIC APPLICATIONS, 2023 VS. 2028 (USD MILLION) 48 FIGURE 13 DONOR RECIPIENT CROSS-MATCHING SEGMENT TO DOMINATE DIAGNOSTIC APPLICATIONS DURING FORECAST PERIOD 48 4.3 HLA TYPING MARKET: ASIA PACIFIC, BY PRODUCT & SERVICE (2022) 49 FIGURE 14 REAGENTS & CONSUMABLES SEGMENT ACCOUNTED FOR LARGEST MARKET SHARE IN CHINA 49 4.4 HLA TYPING MARKET: GEOGRAPHICAL SNAPSHOT 50 FIGURE 15 CHINA TO DOMINATE MARKET DURING FORECAST PERIOD 50 5 MARKET OVERVIEW 51 5.1 INTRODUCTION 51 5.2 MARKET DYNAMICS 51 FIGURE 16 HLA TYPING MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 51 5.2.1 DRIVERS 52 5.2.1.1 Rising number of organ transplantation procedures 52 5.2.1.2 Rising technological advancements in HLA typing 52 5.2.1.3 Increasing funding investments for research activities 53 TABLE 2 PUBLIC-PRIVATE INVESTMENTS AND RESEARCH GRANTS FOR HLA TYPING PRODUCTS, 2019–2022 53 5.2.1.4 Growing prevalence of infectious diseases 53 5.2.2 RESTRAINTS 54 5.2.2.1 High cost of HLA typing products 54 TABLE 3 COST OF ASSAYS FOR KEY NGS AND PCR-BASED GENOMIC TESTS IN EUROPE (AS OF 2020) 54 5.2.2.2 Limited reimbursements for target procedures 55 5.2.3 OPPORTUNITIES 55 5.2.3.1 Rising adoption of cross-matching and chimerism testing procedures 55 5.2.3.2 Growing awareness of organ donations 56 5.2.4 CHALLENGES 56 5.2.4.1 Limited number of organ donations and long waiting lists for transplantations 56 5.2.4.2 Shortage of skilled professionals 56 5.3 PORTER’S FIVE FORCES ANALYSIS 57 TABLE 4 HLA TYPING MARKET: PORTER’S FIVE FORCES ANALYSIS 57 5.3.1 THREAT OF NEW ENTRANTS 57 5.3.2 THREAT OF SUBSTITUTES 57 5.3.3 BARGAINING POWER OF SUPPLIERS 57 5.3.4 BARGAINING POWER OF BUYERS 58 5.3.5 INTENSITY OF COMPETITIVE RIVALRY 58 5.4 REGULATORY ANALYSIS 58 5.4.1 NORTH AMERICA 58 5.4.1.1 US 58 TABLE 5 US FDA: MEDICAL DEVICE CLASSIFICATION 58 TABLE 6 US: MEDICAL DEVICE REGULATORY APPROVAL PROCESS 59 5.4.1.2 Canada 59 TABLE 7 CANADA: MEDICAL DEVICE REGULATORY APPROVAL PROCESS 59 5.4.2 EUROPE 60 5.4.3 ASIA PACIFIC 60 5.4.3.1 Japan 60 TABLE 8 JAPAN: MEDICAL DEVICE CLASSIFICATION UNDER PHARMACEUTICAL AND MEDICAL DEVICE AGENCY (PMDA) 61 5.4.3.2 China 61 TABLE 9 CHINA: CLASSIFICATION OF MEDICAL DEVICES 61 5.4.3.3 India 63 5.5 HLA TYPING MARKET: ECOSYSTEM MAPPING 64 FIGURE 17 ECOSYSTEM COVERAGE 64 5.6 VALUE CHAIN ANALYSIS 64 5.6.1 RESEARCH AND DEVELOPMENT 64 5.6.2 MANUFACTURING AND ASSEMBLY 65 5.6.3 DISTRIBUTION, MARKETING & SALES, AND POST-SALES SERVICES 65 FIGURE 18 VALUE CHAIN ANALYSIS 65 5.7 SUPPLY CHAIN ANALYSIS 65 5.7.1 PROMINENT COMPANIES 65 5.7.2 SMALL AND MEDIUM-SIZED ENTERPRISES 65 FIGURE 19 SUPPLY CHAIN ANALYSIS 66 5.8 KEY STAKEHOLDERS AND BUYING CRITERIA 66 5.8.1 KEY STAKEHOLDERS IN BUYING PROCESS 66 FIGURE 20 INFLUENCE OF STAKEHOLDERS ON BUYING PROCESS 66 TABLE 10 INFLUENCE OF STAKEHOLDERS ON BUYING PROCESS OF HLA TYPING PRODUCTS 67 5.8.2 BUYING CRITERIA 67 FIGURE 21 KEY BUYING CRITERIA FOR HLA TYPING PRODUCTS 67 TABLE 11 KEY BUYING CRITERIA FOR HLA TYPING PRODUCTS 67 5.9 PATENT ANALYSIS 68 FIGURE 22 TOP 10 PATENT APPLICANTS FOR HLA TYPING 68 5.10 IMPACT OF RECESSION ON HLA TYPING MARKET 68 6 HLA TYPING MARKET, BY PRODUCT & SERVICE 69 6.1 INTRODUCTION 70 TABLE 12 HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 70 6.2 REAGENTS & CONSUMABLES 70 6.2.1 WIDE APPLICATIONS OF MOLECULAR ASSAY TECHNIQUES TO DRIVE MARKET 70 TABLE 13 HLA TYPING MARKET FOR REAGENTS & CONSUMABLES, BY REGION, 2021–2028 (USD MILLION) 71 6.3 INSTRUMENTS 71 6.3.1 GROWING ADOPTION OF PCR AND NGS INSTRUMENTS AMONG CROS AND HOSPITALS TO FUEL MARKET 71 TABLE 14 HLA TYPING MARKET FOR INSTRUMENTS, BY REGION, 2021–2028 (USD MILLION) 71 6.4 SOFTWARE & SERVICES 72 6.4.1 RISING DEMAND FOR AUTOMATION AND DIGITALIZATION IN LAB PROCEDURES TO DRIVE MARKET 72 TABLE 15 HLA TYPING MARKET FOR SOFTWARE & SERVICES, BY REGION, 2021–2028 (USD MILLION) 72 7 HLA TYPING MARKET, BY TECHNOLOGY 73 7.1 INTRODUCTION 74 TABLE 16 HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 74 7.2 MOLECULAR ASSAY TECHNOLOGIES 74 TABLE 17 HLA TYPING MARKET FOR MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 75 TABLE 18 HLA TYPING MARKET FOR MOLECULAR ASSAY TECHNOLOGIES, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 75 TABLE 19 HLA TYPING MARKET FOR MOLECULAR ASSAY TECHNOLOGIES, BY APPLICATION, 2021–2028 (USD MILLION) 76 TABLE 20 HLA TYPING MARKET FOR MOLECULAR ASSAY TECHNOLOGIES, BY END USER, 2021–2028 (USD MILLION) 76 TABLE 21 HLA TYPING MARKET FOR MOLECULAR ASSAY TECHNOLOGIES, BY REGION, 2021–2028 (USD MILLION) 76 7.2.1 PCR-BASED MOLECULAR ASSAYS 77 TABLE 22 HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 77 TABLE 23 HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAYS, BY PRODUCT & SERVICE, 2021–2028(USD MILLION) 77 TABLE 24 HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAYS, BY APPLICATION, 2021–2028 (USD MILLION) 78 TABLE 25 HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAYS, BY END USER, 2021–2028 (USD MILLION) 78 TABLE 26 HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAYS, BY REGION, 2021–2028 (USD MILLION) 78 7.2.1.1 Sequence-specific Primer-PCR 79 7.2.1.1.1 Expanding distribution channels of key PCR manufacturers to support market growth 79 TABLE 27 HLA TYPING MARKET FOR SEQUENCE-SPECIFIC PRIMER-PCR, BY REGION, 2021–2028 (USD MILLION) 79 7.2.1.2 Sequence-specific Oligonucleotide-PCR 79 7.2.1.2.1 Rising need for SSO-PCR-based molecular assays in disease diagnosis to drive market 79 TABLE 28 HLA TYPING MARKET FOR SEQUENCE-SPECIFIC OLIGONUCLEOTIDE-PCR, BY REGION, 2021–2028 (USD MILLION) 81 7.2.1.3 Real-time PCR 81 7.2.1.3.1 Increasing preference for genome-based molecular diagnostics to support market growth 81 TABLE 29 HLA TYPING MARKET FOR REAL-TIME PCR, BY REGION, 2021–2028 (USD MILLION) 81 7.2.1.4 Other PCR-based molecular assays 82 TABLE 30 HLA TYPING MARKET FOR OTHER PCR-BASED MOLECULAR ASSAYS, BY REGION, 2021–2028 (USD MILLION) 82 7.2.2 SEQUENCING-BASED MOLECULAR ASSAYS 82 TABLE 31 HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 83 TABLE 32 HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAYS, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 83 TABLE 33 HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAYS, BY APPLICATION, 2021–2028 (USD MILLION) 83 TABLE 34 HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAYS, BY END USER, 2021–2028 (USD MILLION) 84 TABLE 35 HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAYS, BY REGION, 2021–2028 (USD MILLION) 84 7.2.2.1 Sanger sequencing 84 7.2.2.1.1 Rising end-user preference for low-cost and efficient DNA sequencing technology to drive segment growth 84 TABLE 36 HLA TYPING MARKET FOR SANGER SEQUENCING, BY REGION, 2021–2028 (USD MILLION) 85 7.2.2.2 Next-generation Sequencing 85 7.2.2.2.1 High scalability, low turnaround time, and high throughput capabilities to drive segment growth 85 TABLE 37 HLA TYPING MARKET FOR NEXT-GENERATION SEQUENCING, BY REGION, 2021–2028 (USD MILLION) 86 7.2.2.3 Other sequencing-based molecular assays 86 TABLE 38 HLA TYPING MARKET FOR OTHER SEQUENCING-BASED MOLECULAR ASSAYS, BY REGION, 2021–2028 (USD MILLION) 86 7.3 NON-MOLECULAR ASSAY TECHNOLOGIES 87 7.3.1 HIGH PREFERENCE OF MOLECULAR-BASED TECHNIQUES TO RESTRAIN MARKET 87 TABLE 39 HLA TYPING MARKET FOR NON-MOLECULAR ASSAY TECHNOLOGIES, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 87 TABLE 40 HLA TYPING MARKET FOR NON-MOLECULAR ASSAY TECHNOLOGIES, BY APPLICATION, 2021–2028 (USD MILLION) 87 TABLE 41 HLA TYPING MARKET FOR NON-MOLECULAR ASSAY TECHNOLOGIES, BY END USER, 2021–2028 (USD MILLION) 88 TABLE 42 HLA TYPING MARKET FOR NON-MOLECULAR ASSAY TECHNOLOGIES, BY REGION, 2021–2028 (USD MILLION) 88 8 HLA TYPING MARKET, BY APPLICATION 89 8.1 INTRODUCTION 90 TABLE 43 HLA TYPING MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 90 8.2 DIAGNOSTIC APPLICATIONS 90 TABLE 44 HLA TYPING MARKET FOR DIAGNOSTIC APPLICATIONS, BY TYPE, 2021–2028 (USD MILLION) 90 TABLE 45 HLA TYPING MARKET FOR DIAGNOSTIC APPLICATIONS, BY REGION, 2021–2028 (USD MILLION) 91 8.2.1 DONOR-RECIPIENT CROSS-MATCHING 91 8.2.1.1 Rising need for histocompatibility cross-matching in organ transplantation to drive market 91 TABLE 46 HLA TYPING MARKET FOR DONOR-RECIPIENT CROSS-MATCHING, BY REGION, 2021–2028 (USD MILLION) 92 8.2.2 INFECTIOUS DISEASE TESTING 92 8.2.2.1 Rising burden of infectious diseases to drive adoption of HLA antigen screening 92 TABLE 47 HLA TYPING MARKET FOR INFECTIOUS DISEASE TESTING, BY REGION, 2021–2028 (USD MILLION) 93 8.2.3 CANCER DIAGNOSIS & PREVENTION 93 8.2.3.1 Wide availability of advanced NGS techniques to drive adoption of HLA typing in cancer diagnostics 93 TABLE 48 HLA TYPING MARKET FOR CANCER DIAGNOSIS & PREVENTION, BY REGION, 2021–2028 (USD MILLION) 93 8.2.4 TRANSFUSION THERAPY 94 8.2.4.1 Minimal risk of fatal disorders during blood transfusions to drive adoption of HLA typing 94 TABLE 49 HLA TYPING MARKET FOR TRANSFUSION THERAPY, BY REGION, 2021–2028(USD MILLION) 94 8.2.5 OTHER DIAGNOSTIC APPLICATIONS 94 TABLE 50 HLA TYPING MARKET FOR OTHER DIAGNOSTIC APPLICATIONS, BY REGION, 2021–2028 (USD MILLION) 95 8.3 RESEARCH APPLICATIONS 95 8.3.1 RISING FUNDING FOR RESEARCH AND EXPANDING APPLICATIONS OF HLA TYPING TO DRIVE MARKET 95 TABLE 51 HLA TYPING MARKET FOR RESEARCH APPLICATIONS, BY REGION, 2021–2028 (USD MILLION) 96 9 HLA TYPING MARKET, BY END USER 97 9.1 INTRODUCTION 98 TABLE 52 HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 98 9.2 COMMERCIAL SERVICE PROVIDERS 98 9.2.1 RISING ESTABLISHMENT OF REFERENCE LABORATORIES IN EMERGING ECONOMIES TO DRIVE MARKET 98 TABLE 53 HLA TYPING MARKET FOR COMMERCIAL SERVICE PROVIDERS, BY REGION, 2021–2028 (USD MILLION) 99 9.3 HOSPITALS AND TRANSPLANT CENTERS 99 9.3.1 INCREASING DEMAND FOR ADVANCED EQUIPMENT IN HOSPITALS TO DRIVE MARKET 99 TABLE 54 HLA TYPING MARKET FOR HOSPITALS AND TRANSPLANT CENTERS, BY REGION, 2021–2028 (USD MILLION) 99 9.4 RESEARCH LABORATORIES AND ACADEMIC INSTITUTES 100 9.4.1 RISING GOVERNMENT SUPPORT FOR CANCER RESEARCH TO BOOST MARKET GROWTH 100 TABLE 55 HLA TYPING MARKET FOR RESEARCH LABORATORIES AND ACADEMIC INSTITUTES, BY REGION, 2021–2028(USD MILLION) 100 10 HLA TYPING MARKET, BY REGION 101 10.1 INTRODUCTION 102 TABLE 56 HLA TYPING MARKET, BY COUNTRY, 2021–2028 (USD MILLION) 102 10.2 NORTH AMERICA 102 FIGURE 23 HLA TYPING MARKET: NORTH AMERICA SNAPSHOT 103 TABLE 57 NORTH AMERICA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 103 TABLE 58 NORTH AMERICA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 104 TABLE 59 NORTH AMERICA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 104 TABLE 60 NORTH AMERICA: HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 104 TABLE 61 NORTH AMERICA: HLA TYPING MARKET, BY APPLICATION 2021–2028 (USD MILLION) 105 TABLE 62 NORTH AMERICA: HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 105 10.2.1 US 105 10.2.1.1 High volume of stem cell and bone marrow transplantation procedures to drive market 105 TABLE 63 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN US, 2021–2022 106 TABLE 64 NEW CANCER CASES IN US, 2021 106 TABLE 65 US: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 106 TABLE 66 US: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 106 TABLE 67 US: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 107 10.2.2 CANADA 107 10.2.2.1 High prevalence of cancer to drive adoption of HLA typing 107 TABLE 68 CANADA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 107 TABLE 69 CANADA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 108 TABLE 70 CANADA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 108 10.3 EUROPE 108 TABLE 71 EUROPE: HLA TYPING MARKET, BY COUNTRY, 2021–2028 (USD MILLION) 109 TABLE 72 EUROPE: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 109 TABLE 73 EUROPE: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 109 TABLE 74 EUROPE: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 110 TABLE 75 EUROPE: HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 110 TABLE 76 EUROPE: HLA TYPING MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 110 TABLE 77 EUROPE: HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 111 10.3.1 GERMANY 111 10.3.1.1 Strong presence of established manufacturers for HLA typing products to drive market 111 TABLE 78 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN GERMANY, BY TYPE, 2020–2021 111 TABLE 79 TARGET DISEASE INCIDENCE IN GERMANY (2021) 112 TABLE 80 NEW CANCER CASES IN GERMANY, BY ORGAN (2021) 112 TABLE 81 GERMANY: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 112 TABLE 82 GERMANY: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 112 TABLE 83 GERMANY: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 113 10.3.2 UK 113 10.3.2.1 Rising prevalence of autoimmune diseases to drive market 113 TABLE 84 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN UK, 2021–2022 113 TABLE 85 TARGET DISEASE INCIDENCE IN UK, 2021 114 TABLE 86 NEW CANCER CASES IN UK, 2021 114 TABLE 87 UK: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 114 TABLE 88 UK: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 114 TABLE 89 UK: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 115 10.3.3 FRANCE 115 10.3.3.1 Rising organ rejection rate to drive market 115 TABLE 90 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN FRANCE, 2021–2022 115 TABLE 91 NEW CANCER CASES IN FRANCE, 2021 116 TABLE 92 FRANCE: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 116 TABLE 93 FRANCE: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, 2021–2028 (USD MILLION) 116 TABLE 94 FRANCE: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 117 10.3.4 ITALY 117 10.3.4.1 Increasing acceptance of molecular assay technologies for personalized medicine to drive market 117 TABLE 95 ITALY: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 117 TABLE 96 ITALY: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 118 TABLE 97 ITALY: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 118 10.3.5 SPAIN 118 10.3.5.1 Rising number of solid-organ transplantation procedures to support market growth 118 TABLE 98 SPAIN: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 119 TABLE 99 SPAIN: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 119 TABLE 100 SPAIN: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 119 10.3.6 REST OF EUROPE 120 TABLE 101 REST OF EUROPE: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 120 TABLE 102 REST OF EUROPE: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 120 TABLE 103 REST OF EUROPE: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 121 10.4 ASIA PACIFIC 121 FIGURE 24 HLA TYPING MARKET: ASIA PACIFIC SNAPSHOT 122 TABLE 104 ASIA PACIFIC: HLA TYPING MARKET, BY COUNTRY, 2021–2028 (USD MILLION) 122 TABLE 105 ASIA PACIFIC: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 123 TABLE 106 ASIA PACIFIC: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 123 TABLE 107 ASIA PACIFIC: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 123 TABLE 108 ASIA PACIFIC: HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 124 TABLE 109 ASIA PACIFIC: HLA TYPING MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 124 TABLE 110 ASIA PACIFIC: HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 124 10.4.1 CHINA 125 10.4.1.1 Rising adoption of HLA typing for donor-recipient screening to drive market 125 TABLE 111 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN CHINA, 2021–2022 125 TABLE 112 NEW CANCER CASES IN CHINA, 2021 125 TABLE 113 CHINA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 125 TABLE 114 CHINA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 126 TABLE 115 CHINA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 126 10.4.2 INDIA 126 10.4.2.1 Government initiatives to provide free availability of HLA typing products to drive market 126 TABLE 116 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN INDIA, 2021–2022 127 TABLE 117 NEW CANCER CASES IN INDIA, 2021 127 TABLE 118 INDIA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 127 TABLE 119 INDIA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 128 TABLE 120 INDIA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 128 10.4.3 JAPAN 128 10.4.3.1 Increasing budgetary allocations for healthcare to support market growth 128 TABLE 121 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN JAPAN, 2021–2022 129 TABLE 122 NEW CANCER CASES IN JAPAN, 2021 129 TABLE 123 JAPAN: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 129 TABLE 124 JAPAN: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 130 TABLE 125 JAPAN: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 130 10.4.4 AUSTRALIA 130 10.4.4.1 Rising prevalence of coeliac disease to drive adoption of HLA typing 130 TABLE 126 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN AUSTRALIA, 2021–2022 131 TABLE 127 NEW CANCER CASES IN AUSTRALIA, 2021 131 TABLE 128 AUSTRALIA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 131 TABLE 129 AUSTRALIA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 132 TABLE 130 AUSTRALIA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 132 10.4.5 SOUTH KOREA 132 10.4.5.1 Rising adoption of next-generation exome sequencing to drive market 132 TABLE 131 SOUTH KOREA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 133 TABLE 132 SOUTH KOREA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 133 TABLE 133 SOUTH KOREA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 133 10.4.6 REST OF ASIA PACIFIC 134 TABLE 134 REST OF ASIA PACIFIC: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 134 TABLE 135 REST OF ASIA PACIFIC: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 134 TABLE 136 REST OF ASIA PACIFIC: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 135 10.5 LATIN AMERICA 135 TABLE 137 LATIN AMERICA: HLA TYPING MARKET, BY COUNTRY, 2021–2028 (USD MILLION) 135 TABLE 138 LATIN AMERICA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 136 TABLE 139 LATIN AMERICA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 136 TABLE 140 LATIN AMERICA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 136 TABLE 141 LATIN AMERICA: HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 137 TABLE 142 LATIN AMERICA: HLA TYPING MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 137 TABLE 143 LATIN AMERICA: HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 137 10.5.1 BRAZIL 138 10.5.1.1 Supportive government regulations for adoption of advanced technologies to drive market 138 TABLE 144 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN BRAZIL, 2021–2022 138 TABLE 145 NEW CANCER CASES IN BRAZIL, 2021 138 TABLE 146 BRAZIL: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 139 TABLE 147 BRAZIL: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 139 TABLE 148 BRAZIL: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 139 10.5.2 MEXICO 140 10.5.2.1 Improving accessibility and affordability of healthcare services to support market growth 140 TABLE 149 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN MEXICO, 2021–2022 140 TABLE 150 NEW CANCER CASES IN MEXICO, 2021 140 TABLE 151 MEXICO: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 140 TABLE 152 MEXICO: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 141 TABLE 153 MEXICO: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 141 10.5.3 REST OF LATIN AMERICA 141 TABLE 154 REST OF LATIN AMERICA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 142 TABLE 155 REST OF LATIN AMERICA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 142 TABLE 156 REST OF LATIN AMERICA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 142 10.6 MIDDLE EAST AND AFRICA 143 10.6.1 RISING PREVALENCE OF INFECTIOUS DISEASES TO FUEL MARKET 143 TABLE 157 MIDDLE EAST & AFRICA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 143 TABLE 158 MIDDLE EAST & AFRICA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 143 TABLE 159 MIDDLE EAST & AFRICA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 143 TABLE 160 MIDDLE EAST & AFRICA: HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 144 TABLE 161 MIDDLE EAST & AFRICA: HLA TYPING MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 144 TABLE 162 MIDDLE EAST & AFRICA: HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 145 11 COMPETITIVE LANDSCAPE 146 11.1 INTRODUCTION 146 11.2 STRATEGIES ADOPTED BY KEY PLAYERS 146 TABLE 163 HLA TYPING MARKET: OVERVIEW OF STRATEGIES ADOPTED BY KEY PLAYERS 147 11.3 MARKET SHARE ANALYSIS 147 FIGURE 25 HLA TYPING MARKET SHARE ANALYSIS, BY KEY PLAYER (2021) 147 11.4 COMPETITIVE LEADERSHIP MAPPING 148 11.4.1 STARS 149 11.4.2 EMERGING LEADERS 149 11.4.3 PERVASIVE PLAYERS 149 11.4.4 PARTICIPANTS 150 FIGURE 26 HLA TYPING MARKET: COMPETITIVE LEADERSHIP MAPPING (2021) 150 11.5 COMPANY EVALUATION MATRIX FOR STARTUPS/SMES (2021) 151 11.5.1 PROGRESSIVE COMPANIES 151 11.5.2 RESPONSIVE COMPANIES 151 11.5.3 DYNAMIC COMPANIES 151 11.5.4 STARTING BLOCKS 151 FIGURE 27 HLA TYPING MARKET: COMPANY EVALUATION MATRIX FOR SMES/STARTUPS, 2021 152 11.6 COMPETITIVE BENCHMARKING 152 TABLE 164 HLA TYPING MARKET: PRODUCT ANALYSIS FOR KEY PLAYERS 152 TABLE 165 HLA TYPING MARKET: APPLICATION FOOTPRINT ANALYSIS FOR KEY PLAYERS 153 TABLE 166 HLA TYPING MARKET: REGIONAL FOOTPRINT ANALYSIS OF KEY PLAYERS 154 11.7 COMPETITIVE SCENARIO 155 11.7.1 PRODUCT LAUNCHES 155 TABLE 167 HLA TYPING MARKET: PRODUCT LAUNCHES (2019–2022) 155 11.7.2 DEALS 156 TABLE 168 HLA TYPING MARKET: DEALS (2019–2022) 156 12 COMPANY PROFILES 158 12.1 KEY PLAYERS 158 (Business Overview, Products Offered, Recent Developments, and MnM View (Key strengths/Right to Win, Strategic Choices Made, and Weaknesses and Competitive Threats))* 12.1.1 BD 158 TABLE 169 BD: COMPANY OVERVIEW (2021) 158 FIGURE 28 BD: COMPANY SNAPSHOT (2021) 159 12.1.2 BIO-RAD LABORATORIES, INC. 162 TABLE 170 BIO-RAD LABORATORIES, INC.: COMPANY OVERVIEW (2021) 162 FIGURE 29 BIO-RAD LABORATORIES, INC.: COMPANY SNAPSHOT (2021) 163 12.1.3 F. HOFFMAN-LA ROCHE LTD. 167 TABLE 171 F. HOFFMAN-LA ROCHE LTD: COMPANY OVERVIEW (2021) 167 FIGURE 30 F. HOFFMAN-LA ROCHE LTD: COMPANY SNAPSHOT (2021) 168 12.1.4 CAREDX, INC. 172 TABLE 172 CAREDX, INC.: COMPANY OVERVIEW (2021) 172 FIGURE 31 CAREDX, INC.: COMPANY SNAPSHOT (2021) 173 12.1.5 HOLOGIC, INC. 176 TABLE 173 HOLOGIC, INC.: COMPANY OVERVIEW (2021) 176 FIGURE 32 HOLOGIC, INC.: COMPANY SNAPSHOT (2021) 177 12.1.6 ILLUMINA, INC. 179 TABLE 174 ILLUMINA, INC.: COMPANY OVERVIEW (2021) 179 FIGURE 33 ILLUMINA, INC.: COMPANY SNAPSHOT (2021) 180 12.1.7 IMMUCOR, INC. 183 TABLE 175 IMMUCOR, INC.: COMPANY OVERVIEW (2021) 183 FIGURE 34 IMMUCOR, INC.: COMPANY SNAPSHOT (2021) 184 12.1.8 OMIXON INC. 188 TABLE 176 OMIXON INC.: COMPANY OVERVIEW (2021) 188 12.1.9 QIAGEN N.V. 190 TABLE 177 QIAGEN N.V.: COMPANY OVERVIEW (2021) 190 FIGURE 35 QIAGEN N.V.: COMPANY SNAPSHOT (2021) 191 12.1.10 TAKARA BIO INC. 197 TABLE 178 TAKARA BIO INC.: COMPANY OVERVIEW (2021) 197 FIGURE 36 TAKARA BIO, INC: COMPANY SNAPSHOT (2021) 197 12.1.11 THERMO FISHER SCIENTIFIC 199 TABLE 179 THERMO FISHER SCIENTIFIC: COMPANY OVERVIEW (2021) 199 FIGURE 37 THERMO FISHER SCIENTIFIC: COMPANY SNAPSHOT (2021) 200 12.1.12 BIOFORTUNA LIMITED 204 12.1.13 GENDX 205 TABLE 180 GENDX: COMPANY OVERVIEW (2021) 205 12.2 OTHER PLAYERS 207 12.2.1 FUJIREBIO 207 12.2.2 CREATIVE BIOLABS 207 12.2.3 ALPHA BIOTECH LIMITED 208 12.2.4 BAG DIAGNOSTICS GMBH 209 12.2.5 HANSA BIOPHARMA AB 210 12.2.6 HISTOGENETICS LLC 210 12.2.7 PACBIO 211 12.2.8 TBG DIAGNOSTICS LIMITED 212 12.2.9 INNO-TRAIN DIAGNOSTIK GMBH 212 12.2.10 KRISHGEN BIOSYSTEMS 213 *Details on Business Overview, Products Offered, Recent Developments, and MnM View (Key strengths/Right to Win, Strategic Choices Made, and Weaknesses and Competitive Threats) might not be captured in case of unlisted companies. 13 APPENDIX 214 13.1 DISCUSSION GUIDE 214 13.2 KNOWLEDGESTORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL 220 13.3 CUSTOMIZATION OPTIONS 222 13.4 RELATED REPORTS 222 13.5 AUTHOR DETAILS 223
SummaryThe HLA typing market is projected to reach USD 2.1 billion in 2028 from USD 1.4 billion in 2022 with a CAGR of 6.5% during the forecast period. The need and strong demand for clinical diagnostic procedures that can provide early diagnosis of infectious diseases, graft rejections, autoimmune diseases, and cancer have supported rising research activities. According to the Journal of Human Genetics (2015), research on the human leukocyte antigen (HLA) molecule (involved in immunity) has benefitted greatly from NGS technologies. Thus, several high-throughput HLA-typing methods using NGS have been developed, as NGS technology enables complete HLA sequencing mechanisms, facilitating the understanding of HLA gene modulation, including transcription, regulation of gene expression, and epigenetics. Thus, government organizations and private players increasingly support research activities that target gene profiling and cross-matching in prospective subjects. Table of Contents1 INTRODUCTION 271.1 STUDY OBJECTIVES 27 1.2 MARKET DEFINITION 27 1.2.1 INCLUSIONS AND EXCLUSIONS 27 1.3 MARKET SCOPE 28 1.3.1 MARKETS COVERED 28 1.3.2 GEOGRAPHIES COVERED 28 1.3.3 YEARS CONSIDERED 29 1.4 CURRENCY CONSIDERED 29 1.5 STAKEHOLDERS 29 1.6 SUMMARY OF CHANGES 30 2 RESEARCH METHODOLOGY 31 2.1 RESEARCH DATA 31 FIGURE 1 HLA TYPING MARKET: RESEARCH METHODOLOGY 31 2.1.1 SECONDARY DATA 32 2.1.1.1 Key data from secondary sources 32 2.1.2 PRIMARY DATA 33 FIGURE 2 PRIMARY SOURCES 33 2.1.2.1 Key data from primary sources 34 2.1.2.2 Insights from primary experts 35 2.1.2.3 Breakdown of primary interviews 35 FIGURE 3 BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY TYPE, DESIGNATION, AND REGION 36 2.2 MARKET SIZE ESTIMATION 36 FIGURE 4 MARKET SIZE ESTIMATION: REVENUE SHARE ANALYSIS 37 FIGURE 5 TOP-DOWN APPROACH 38 2.3 MARKET BREAKDOWN AND DATA TRIANGULATION 40 FIGURE 6 DATA TRIANGULATION METHODOLOGY 40 2.4 MARKET SHARE ESTIMATION 41 2.5 RESEARCH ASSUMPTIONS 41 2.6 LIMITATIONS 41 2.6.1 METHODOLOGY-RELATED LIMITATIONS 41 2.7 RISK ASSESSMENT 42 TABLE 1 LIMITATIONS AND ASSOCIATED RISKS 42 2.8 HLA TYPING MARKET: RECESSION IMPACT 42 3 EXECUTIVE SUMMARY 43 FIGURE 7 HLA TYPING MARKET, BY TECHNOLOGY, 2023 VS. 2028 (USD MILLION) 43 FIGURE 8 HLA TYPING MARKET, BY PRODUCT & SERVICE, 2023 VS. 2028 (USD MILLION) 44 FIGURE 9 HLA TYPING MARKET, BY END USER, 2023 VS. 2028 (USD MILLION) 44 FIGURE 10 HLA TYPING MARKET, BY APPLICATION, 2023 VS. 2028 (USD MILLION) 45 FIGURE 11 ASIA PACIFIC REGION TO DOMINATE MARKET DURING FORECAST PERIOD 46 4 PREMIUM INSIGHTS 47 4.1 HLA TYPING MARKET OVERVIEW 47 FIGURE 12 INCREASING NUMBER OF ORGAN TRANSPLANTATIONS AND RISING ADOPTION OF DONOR RECIPIENT CROSS-MATCHING TO DRIVE MARKET 47 4.2 HLA TYPING MARKET, BY DIAGNOSTIC APPLICATIONS, 2023 VS. 2028 (USD MILLION) 48 FIGURE 13 DONOR RECIPIENT CROSS-MATCHING SEGMENT TO DOMINATE DIAGNOSTIC APPLICATIONS DURING FORECAST PERIOD 48 4.3 HLA TYPING MARKET: ASIA PACIFIC, BY PRODUCT & SERVICE (2022) 49 FIGURE 14 REAGENTS & CONSUMABLES SEGMENT ACCOUNTED FOR LARGEST MARKET SHARE IN CHINA 49 4.4 HLA TYPING MARKET: GEOGRAPHICAL SNAPSHOT 50 FIGURE 15 CHINA TO DOMINATE MARKET DURING FORECAST PERIOD 50 5 MARKET OVERVIEW 51 5.1 INTRODUCTION 51 5.2 MARKET DYNAMICS 51 FIGURE 16 HLA TYPING MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 51 5.2.1 DRIVERS 52 5.2.1.1 Rising number of organ transplantation procedures 52 5.2.1.2 Rising technological advancements in HLA typing 52 5.2.1.3 Increasing funding investments for research activities 53 TABLE 2 PUBLIC-PRIVATE INVESTMENTS AND RESEARCH GRANTS FOR HLA TYPING PRODUCTS, 2019–2022 53 5.2.1.4 Growing prevalence of infectious diseases 53 5.2.2 RESTRAINTS 54 5.2.2.1 High cost of HLA typing products 54 TABLE 3 COST OF ASSAYS FOR KEY NGS AND PCR-BASED GENOMIC TESTS IN EUROPE (AS OF 2020) 54 5.2.2.2 Limited reimbursements for target procedures 55 5.2.3 OPPORTUNITIES 55 5.2.3.1 Rising adoption of cross-matching and chimerism testing procedures 55 5.2.3.2 Growing awareness of organ donations 56 5.2.4 CHALLENGES 56 5.2.4.1 Limited number of organ donations and long waiting lists for transplantations 56 5.2.4.2 Shortage of skilled professionals 56 5.3 PORTER’S FIVE FORCES ANALYSIS 57 TABLE 4 HLA TYPING MARKET: PORTER’S FIVE FORCES ANALYSIS 57 5.3.1 THREAT OF NEW ENTRANTS 57 5.3.2 THREAT OF SUBSTITUTES 57 5.3.3 BARGAINING POWER OF SUPPLIERS 57 5.3.4 BARGAINING POWER OF BUYERS 58 5.3.5 INTENSITY OF COMPETITIVE RIVALRY 58 5.4 REGULATORY ANALYSIS 58 5.4.1 NORTH AMERICA 58 5.4.1.1 US 58 TABLE 5 US FDA: MEDICAL DEVICE CLASSIFICATION 58 TABLE 6 US: MEDICAL DEVICE REGULATORY APPROVAL PROCESS 59 5.4.1.2 Canada 59 TABLE 7 CANADA: MEDICAL DEVICE REGULATORY APPROVAL PROCESS 59 5.4.2 EUROPE 60 5.4.3 ASIA PACIFIC 60 5.4.3.1 Japan 60 TABLE 8 JAPAN: MEDICAL DEVICE CLASSIFICATION UNDER PHARMACEUTICAL AND MEDICAL DEVICE AGENCY (PMDA) 61 5.4.3.2 China 61 TABLE 9 CHINA: CLASSIFICATION OF MEDICAL DEVICES 61 5.4.3.3 India 63 5.5 HLA TYPING MARKET: ECOSYSTEM MAPPING 64 FIGURE 17 ECOSYSTEM COVERAGE 64 5.6 VALUE CHAIN ANALYSIS 64 5.6.1 RESEARCH AND DEVELOPMENT 64 5.6.2 MANUFACTURING AND ASSEMBLY 65 5.6.3 DISTRIBUTION, MARKETING & SALES, AND POST-SALES SERVICES 65 FIGURE 18 VALUE CHAIN ANALYSIS 65 5.7 SUPPLY CHAIN ANALYSIS 65 5.7.1 PROMINENT COMPANIES 65 5.7.2 SMALL AND MEDIUM-SIZED ENTERPRISES 65 FIGURE 19 SUPPLY CHAIN ANALYSIS 66 5.8 KEY STAKEHOLDERS AND BUYING CRITERIA 66 5.8.1 KEY STAKEHOLDERS IN BUYING PROCESS 66 FIGURE 20 INFLUENCE OF STAKEHOLDERS ON BUYING PROCESS 66 TABLE 10 INFLUENCE OF STAKEHOLDERS ON BUYING PROCESS OF HLA TYPING PRODUCTS 67 5.8.2 BUYING CRITERIA 67 FIGURE 21 KEY BUYING CRITERIA FOR HLA TYPING PRODUCTS 67 TABLE 11 KEY BUYING CRITERIA FOR HLA TYPING PRODUCTS 67 5.9 PATENT ANALYSIS 68 FIGURE 22 TOP 10 PATENT APPLICANTS FOR HLA TYPING 68 5.10 IMPACT OF RECESSION ON HLA TYPING MARKET 68 6 HLA TYPING MARKET, BY PRODUCT & SERVICE 69 6.1 INTRODUCTION 70 TABLE 12 HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 70 6.2 REAGENTS & CONSUMABLES 70 6.2.1 WIDE APPLICATIONS OF MOLECULAR ASSAY TECHNIQUES TO DRIVE MARKET 70 TABLE 13 HLA TYPING MARKET FOR REAGENTS & CONSUMABLES, BY REGION, 2021–2028 (USD MILLION) 71 6.3 INSTRUMENTS 71 6.3.1 GROWING ADOPTION OF PCR AND NGS INSTRUMENTS AMONG CROS AND HOSPITALS TO FUEL MARKET 71 TABLE 14 HLA TYPING MARKET FOR INSTRUMENTS, BY REGION, 2021–2028 (USD MILLION) 71 6.4 SOFTWARE & SERVICES 72 6.4.1 RISING DEMAND FOR AUTOMATION AND DIGITALIZATION IN LAB PROCEDURES TO DRIVE MARKET 72 TABLE 15 HLA TYPING MARKET FOR SOFTWARE & SERVICES, BY REGION, 2021–2028 (USD MILLION) 72 7 HLA TYPING MARKET, BY TECHNOLOGY 73 7.1 INTRODUCTION 74 TABLE 16 HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 74 7.2 MOLECULAR ASSAY TECHNOLOGIES 74 TABLE 17 HLA TYPING MARKET FOR MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 75 TABLE 18 HLA TYPING MARKET FOR MOLECULAR ASSAY TECHNOLOGIES, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 75 TABLE 19 HLA TYPING MARKET FOR MOLECULAR ASSAY TECHNOLOGIES, BY APPLICATION, 2021–2028 (USD MILLION) 76 TABLE 20 HLA TYPING MARKET FOR MOLECULAR ASSAY TECHNOLOGIES, BY END USER, 2021–2028 (USD MILLION) 76 TABLE 21 HLA TYPING MARKET FOR MOLECULAR ASSAY TECHNOLOGIES, BY REGION, 2021–2028 (USD MILLION) 76 7.2.1 PCR-BASED MOLECULAR ASSAYS 77 TABLE 22 HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 77 TABLE 23 HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAYS, BY PRODUCT & SERVICE, 2021–2028(USD MILLION) 77 TABLE 24 HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAYS, BY APPLICATION, 2021–2028 (USD MILLION) 78 TABLE 25 HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAYS, BY END USER, 2021–2028 (USD MILLION) 78 TABLE 26 HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAYS, BY REGION, 2021–2028 (USD MILLION) 78 7.2.1.1 Sequence-specific Primer-PCR 79 7.2.1.1.1 Expanding distribution channels of key PCR manufacturers to support market growth 79 TABLE 27 HLA TYPING MARKET FOR SEQUENCE-SPECIFIC PRIMER-PCR, BY REGION, 2021–2028 (USD MILLION) 79 7.2.1.2 Sequence-specific Oligonucleotide-PCR 79 7.2.1.2.1 Rising need for SSO-PCR-based molecular assays in disease diagnosis to drive market 79 TABLE 28 HLA TYPING MARKET FOR SEQUENCE-SPECIFIC OLIGONUCLEOTIDE-PCR, BY REGION, 2021–2028 (USD MILLION) 81 7.2.1.3 Real-time PCR 81 7.2.1.3.1 Increasing preference for genome-based molecular diagnostics to support market growth 81 TABLE 29 HLA TYPING MARKET FOR REAL-TIME PCR, BY REGION, 2021–2028 (USD MILLION) 81 7.2.1.4 Other PCR-based molecular assays 82 TABLE 30 HLA TYPING MARKET FOR OTHER PCR-BASED MOLECULAR ASSAYS, BY REGION, 2021–2028 (USD MILLION) 82 7.2.2 SEQUENCING-BASED MOLECULAR ASSAYS 82 TABLE 31 HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 83 TABLE 32 HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAYS, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 83 TABLE 33 HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAYS, BY APPLICATION, 2021–2028 (USD MILLION) 83 TABLE 34 HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAYS, BY END USER, 2021–2028 (USD MILLION) 84 TABLE 35 HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAYS, BY REGION, 2021–2028 (USD MILLION) 84 7.2.2.1 Sanger sequencing 84 7.2.2.1.1 Rising end-user preference for low-cost and efficient DNA sequencing technology to drive segment growth 84 TABLE 36 HLA TYPING MARKET FOR SANGER SEQUENCING, BY REGION, 2021–2028 (USD MILLION) 85 7.2.2.2 Next-generation Sequencing 85 7.2.2.2.1 High scalability, low turnaround time, and high throughput capabilities to drive segment growth 85 TABLE 37 HLA TYPING MARKET FOR NEXT-GENERATION SEQUENCING, BY REGION, 2021–2028 (USD MILLION) 86 7.2.2.3 Other sequencing-based molecular assays 86 TABLE 38 HLA TYPING MARKET FOR OTHER SEQUENCING-BASED MOLECULAR ASSAYS, BY REGION, 2021–2028 (USD MILLION) 86 7.3 NON-MOLECULAR ASSAY TECHNOLOGIES 87 7.3.1 HIGH PREFERENCE OF MOLECULAR-BASED TECHNIQUES TO RESTRAIN MARKET 87 TABLE 39 HLA TYPING MARKET FOR NON-MOLECULAR ASSAY TECHNOLOGIES, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 87 TABLE 40 HLA TYPING MARKET FOR NON-MOLECULAR ASSAY TECHNOLOGIES, BY APPLICATION, 2021–2028 (USD MILLION) 87 TABLE 41 HLA TYPING MARKET FOR NON-MOLECULAR ASSAY TECHNOLOGIES, BY END USER, 2021–2028 (USD MILLION) 88 TABLE 42 HLA TYPING MARKET FOR NON-MOLECULAR ASSAY TECHNOLOGIES, BY REGION, 2021–2028 (USD MILLION) 88 8 HLA TYPING MARKET, BY APPLICATION 89 8.1 INTRODUCTION 90 TABLE 43 HLA TYPING MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 90 8.2 DIAGNOSTIC APPLICATIONS 90 TABLE 44 HLA TYPING MARKET FOR DIAGNOSTIC APPLICATIONS, BY TYPE, 2021–2028 (USD MILLION) 90 TABLE 45 HLA TYPING MARKET FOR DIAGNOSTIC APPLICATIONS, BY REGION, 2021–2028 (USD MILLION) 91 8.2.1 DONOR-RECIPIENT CROSS-MATCHING 91 8.2.1.1 Rising need for histocompatibility cross-matching in organ transplantation to drive market 91 TABLE 46 HLA TYPING MARKET FOR DONOR-RECIPIENT CROSS-MATCHING, BY REGION, 2021–2028 (USD MILLION) 92 8.2.2 INFECTIOUS DISEASE TESTING 92 8.2.2.1 Rising burden of infectious diseases to drive adoption of HLA antigen screening 92 TABLE 47 HLA TYPING MARKET FOR INFECTIOUS DISEASE TESTING, BY REGION, 2021–2028 (USD MILLION) 93 8.2.3 CANCER DIAGNOSIS & PREVENTION 93 8.2.3.1 Wide availability of advanced NGS techniques to drive adoption of HLA typing in cancer diagnostics 93 TABLE 48 HLA TYPING MARKET FOR CANCER DIAGNOSIS & PREVENTION, BY REGION, 2021–2028 (USD MILLION) 93 8.2.4 TRANSFUSION THERAPY 94 8.2.4.1 Minimal risk of fatal disorders during blood transfusions to drive adoption of HLA typing 94 TABLE 49 HLA TYPING MARKET FOR TRANSFUSION THERAPY, BY REGION, 2021–2028(USD MILLION) 94 8.2.5 OTHER DIAGNOSTIC APPLICATIONS 94 TABLE 50 HLA TYPING MARKET FOR OTHER DIAGNOSTIC APPLICATIONS, BY REGION, 2021–2028 (USD MILLION) 95 8.3 RESEARCH APPLICATIONS 95 8.3.1 RISING FUNDING FOR RESEARCH AND EXPANDING APPLICATIONS OF HLA TYPING TO DRIVE MARKET 95 TABLE 51 HLA TYPING MARKET FOR RESEARCH APPLICATIONS, BY REGION, 2021–2028 (USD MILLION) 96 9 HLA TYPING MARKET, BY END USER 97 9.1 INTRODUCTION 98 TABLE 52 HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 98 9.2 COMMERCIAL SERVICE PROVIDERS 98 9.2.1 RISING ESTABLISHMENT OF REFERENCE LABORATORIES IN EMERGING ECONOMIES TO DRIVE MARKET 98 TABLE 53 HLA TYPING MARKET FOR COMMERCIAL SERVICE PROVIDERS, BY REGION, 2021–2028 (USD MILLION) 99 9.3 HOSPITALS AND TRANSPLANT CENTERS 99 9.3.1 INCREASING DEMAND FOR ADVANCED EQUIPMENT IN HOSPITALS TO DRIVE MARKET 99 TABLE 54 HLA TYPING MARKET FOR HOSPITALS AND TRANSPLANT CENTERS, BY REGION, 2021–2028 (USD MILLION) 99 9.4 RESEARCH LABORATORIES AND ACADEMIC INSTITUTES 100 9.4.1 RISING GOVERNMENT SUPPORT FOR CANCER RESEARCH TO BOOST MARKET GROWTH 100 TABLE 55 HLA TYPING MARKET FOR RESEARCH LABORATORIES AND ACADEMIC INSTITUTES, BY REGION, 2021–2028(USD MILLION) 100 10 HLA TYPING MARKET, BY REGION 101 10.1 INTRODUCTION 102 TABLE 56 HLA TYPING MARKET, BY COUNTRY, 2021–2028 (USD MILLION) 102 10.2 NORTH AMERICA 102 FIGURE 23 HLA TYPING MARKET: NORTH AMERICA SNAPSHOT 103 TABLE 57 NORTH AMERICA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 103 TABLE 58 NORTH AMERICA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 104 TABLE 59 NORTH AMERICA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 104 TABLE 60 NORTH AMERICA: HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 104 TABLE 61 NORTH AMERICA: HLA TYPING MARKET, BY APPLICATION 2021–2028 (USD MILLION) 105 TABLE 62 NORTH AMERICA: HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 105 10.2.1 US 105 10.2.1.1 High volume of stem cell and bone marrow transplantation procedures to drive market 105 TABLE 63 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN US, 2021–2022 106 TABLE 64 NEW CANCER CASES IN US, 2021 106 TABLE 65 US: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 106 TABLE 66 US: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 106 TABLE 67 US: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 107 10.2.2 CANADA 107 10.2.2.1 High prevalence of cancer to drive adoption of HLA typing 107 TABLE 68 CANADA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 107 TABLE 69 CANADA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 108 TABLE 70 CANADA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 108 10.3 EUROPE 108 TABLE 71 EUROPE: HLA TYPING MARKET, BY COUNTRY, 2021–2028 (USD MILLION) 109 TABLE 72 EUROPE: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 109 TABLE 73 EUROPE: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 109 TABLE 74 EUROPE: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 110 TABLE 75 EUROPE: HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 110 TABLE 76 EUROPE: HLA TYPING MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 110 TABLE 77 EUROPE: HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 111 10.3.1 GERMANY 111 10.3.1.1 Strong presence of established manufacturers for HLA typing products to drive market 111 TABLE 78 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN GERMANY, BY TYPE, 2020–2021 111 TABLE 79 TARGET DISEASE INCIDENCE IN GERMANY (2021) 112 TABLE 80 NEW CANCER CASES IN GERMANY, BY ORGAN (2021) 112 TABLE 81 GERMANY: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 112 TABLE 82 GERMANY: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 112 TABLE 83 GERMANY: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 113 10.3.2 UK 113 10.3.2.1 Rising prevalence of autoimmune diseases to drive market 113 TABLE 84 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN UK, 2021–2022 113 TABLE 85 TARGET DISEASE INCIDENCE IN UK, 2021 114 TABLE 86 NEW CANCER CASES IN UK, 2021 114 TABLE 87 UK: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 114 TABLE 88 UK: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 114 TABLE 89 UK: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 115 10.3.3 FRANCE 115 10.3.3.1 Rising organ rejection rate to drive market 115 TABLE 90 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN FRANCE, 2021–2022 115 TABLE 91 NEW CANCER CASES IN FRANCE, 2021 116 TABLE 92 FRANCE: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 116 TABLE 93 FRANCE: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, 2021–2028 (USD MILLION) 116 TABLE 94 FRANCE: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 117 10.3.4 ITALY 117 10.3.4.1 Increasing acceptance of molecular assay technologies for personalized medicine to drive market 117 TABLE 95 ITALY: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 117 TABLE 96 ITALY: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 118 TABLE 97 ITALY: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 118 10.3.5 SPAIN 118 10.3.5.1 Rising number of solid-organ transplantation procedures to support market growth 118 TABLE 98 SPAIN: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 119 TABLE 99 SPAIN: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 119 TABLE 100 SPAIN: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 119 10.3.6 REST OF EUROPE 120 TABLE 101 REST OF EUROPE: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 120 TABLE 102 REST OF EUROPE: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 120 TABLE 103 REST OF EUROPE: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 121 10.4 ASIA PACIFIC 121 FIGURE 24 HLA TYPING MARKET: ASIA PACIFIC SNAPSHOT 122 TABLE 104 ASIA PACIFIC: HLA TYPING MARKET, BY COUNTRY, 2021–2028 (USD MILLION) 122 TABLE 105 ASIA PACIFIC: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 123 TABLE 106 ASIA PACIFIC: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 123 TABLE 107 ASIA PACIFIC: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 123 TABLE 108 ASIA PACIFIC: HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 124 TABLE 109 ASIA PACIFIC: HLA TYPING MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 124 TABLE 110 ASIA PACIFIC: HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 124 10.4.1 CHINA 125 10.4.1.1 Rising adoption of HLA typing for donor-recipient screening to drive market 125 TABLE 111 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN CHINA, 2021–2022 125 TABLE 112 NEW CANCER CASES IN CHINA, 2021 125 TABLE 113 CHINA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 125 TABLE 114 CHINA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 126 TABLE 115 CHINA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 126 10.4.2 INDIA 126 10.4.2.1 Government initiatives to provide free availability of HLA typing products to drive market 126 TABLE 116 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN INDIA, 2021–2022 127 TABLE 117 NEW CANCER CASES IN INDIA, 2021 127 TABLE 118 INDIA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 127 TABLE 119 INDIA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 128 TABLE 120 INDIA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 128 10.4.3 JAPAN 128 10.4.3.1 Increasing budgetary allocations for healthcare to support market growth 128 TABLE 121 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN JAPAN, 2021–2022 129 TABLE 122 NEW CANCER CASES IN JAPAN, 2021 129 TABLE 123 JAPAN: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 129 TABLE 124 JAPAN: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 130 TABLE 125 JAPAN: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 130 10.4.4 AUSTRALIA 130 10.4.4.1 Rising prevalence of coeliac disease to drive adoption of HLA typing 130 TABLE 126 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN AUSTRALIA, 2021–2022 131 TABLE 127 NEW CANCER CASES IN AUSTRALIA, 2021 131 TABLE 128 AUSTRALIA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 131 TABLE 129 AUSTRALIA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 132 TABLE 130 AUSTRALIA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 132 10.4.5 SOUTH KOREA 132 10.4.5.1 Rising adoption of next-generation exome sequencing to drive market 132 TABLE 131 SOUTH KOREA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 133 TABLE 132 SOUTH KOREA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 133 TABLE 133 SOUTH KOREA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 133 10.4.6 REST OF ASIA PACIFIC 134 TABLE 134 REST OF ASIA PACIFIC: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 134 TABLE 135 REST OF ASIA PACIFIC: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 134 TABLE 136 REST OF ASIA PACIFIC: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 135 10.5 LATIN AMERICA 135 TABLE 137 LATIN AMERICA: HLA TYPING MARKET, BY COUNTRY, 2021–2028 (USD MILLION) 135 TABLE 138 LATIN AMERICA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 136 TABLE 139 LATIN AMERICA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 136 TABLE 140 LATIN AMERICA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 136 TABLE 141 LATIN AMERICA: HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 137 TABLE 142 LATIN AMERICA: HLA TYPING MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 137 TABLE 143 LATIN AMERICA: HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 137 10.5.1 BRAZIL 138 10.5.1.1 Supportive government regulations for adoption of advanced technologies to drive market 138 TABLE 144 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN BRAZIL, 2021–2022 138 TABLE 145 NEW CANCER CASES IN BRAZIL, 2021 138 TABLE 146 BRAZIL: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 139 TABLE 147 BRAZIL: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 139 TABLE 148 BRAZIL: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 139 10.5.2 MEXICO 140 10.5.2.1 Improving accessibility and affordability of healthcare services to support market growth 140 TABLE 149 SOLID-ORGAN TRANSPLANTATIONS PERFORMED IN MEXICO, 2021–2022 140 TABLE 150 NEW CANCER CASES IN MEXICO, 2021 140 TABLE 151 MEXICO: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 140 TABLE 152 MEXICO: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 141 TABLE 153 MEXICO: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 141 10.5.3 REST OF LATIN AMERICA 141 TABLE 154 REST OF LATIN AMERICA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 142 TABLE 155 REST OF LATIN AMERICA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 142 TABLE 156 REST OF LATIN AMERICA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 142 10.6 MIDDLE EAST AND AFRICA 143 10.6.1 RISING PREVALENCE OF INFECTIOUS DISEASES TO FUEL MARKET 143 TABLE 157 MIDDLE EAST & AFRICA: HLA TYPING MARKET, BY TECHNOLOGY, 2021–2028 (USD MILLION) 143 TABLE 158 MIDDLE EAST & AFRICA: HLA TYPING MARKET FOR PCR-BASED MOLECULAR ASSAY TECHNOLOGIES, BY TYPE, 2021–2028 (USD MILLION) 143 TABLE 159 MIDDLE EAST & AFRICA: HLA TYPING MARKET FOR SEQUENCING-BASED MOLECULAR ASSAY TECHNOLOGIES ASSAYS, BY TYPE, 2021–2028 (USD MILLION) 143 TABLE 160 MIDDLE EAST & AFRICA: HLA TYPING MARKET, BY PRODUCT & SERVICE, 2021–2028 (USD MILLION) 144 TABLE 161 MIDDLE EAST & AFRICA: HLA TYPING MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 144 TABLE 162 MIDDLE EAST & AFRICA: HLA TYPING MARKET, BY END USER, 2021–2028 (USD MILLION) 145 11 COMPETITIVE LANDSCAPE 146 11.1 INTRODUCTION 146 11.2 STRATEGIES ADOPTED BY KEY PLAYERS 146 TABLE 163 HLA TYPING MARKET: OVERVIEW OF STRATEGIES ADOPTED BY KEY PLAYERS 147 11.3 MARKET SHARE ANALYSIS 147 FIGURE 25 HLA TYPING MARKET SHARE ANALYSIS, BY KEY PLAYER (2021) 147 11.4 COMPETITIVE LEADERSHIP MAPPING 148 11.4.1 STARS 149 11.4.2 EMERGING LEADERS 149 11.4.3 PERVASIVE PLAYERS 149 11.4.4 PARTICIPANTS 150 FIGURE 26 HLA TYPING MARKET: COMPETITIVE LEADERSHIP MAPPING (2021) 150 11.5 COMPANY EVALUATION MATRIX FOR STARTUPS/SMES (2021) 151 11.5.1 PROGRESSIVE COMPANIES 151 11.5.2 RESPONSIVE COMPANIES 151 11.5.3 DYNAMIC COMPANIES 151 11.5.4 STARTING BLOCKS 151 FIGURE 27 HLA TYPING MARKET: COMPANY EVALUATION MATRIX FOR SMES/STARTUPS, 2021 152 11.6 COMPETITIVE BENCHMARKING 152 TABLE 164 HLA TYPING MARKET: PRODUCT ANALYSIS FOR KEY PLAYERS 152 TABLE 165 HLA TYPING MARKET: APPLICATION FOOTPRINT ANALYSIS FOR KEY PLAYERS 153 TABLE 166 HLA TYPING MARKET: REGIONAL FOOTPRINT ANALYSIS OF KEY PLAYERS 154 11.7 COMPETITIVE SCENARIO 155 11.7.1 PRODUCT LAUNCHES 155 TABLE 167 HLA TYPING MARKET: PRODUCT LAUNCHES (2019–2022) 155 11.7.2 DEALS 156 TABLE 168 HLA TYPING MARKET: DEALS (2019–2022) 156 12 COMPANY PROFILES 158 12.1 KEY PLAYERS 158 (Business Overview, Products Offered, Recent Developments, and MnM View (Key strengths/Right to Win, Strategic Choices Made, and Weaknesses and Competitive Threats))* 12.1.1 BD 158 TABLE 169 BD: COMPANY OVERVIEW (2021) 158 FIGURE 28 BD: COMPANY SNAPSHOT (2021) 159 12.1.2 BIO-RAD LABORATORIES, INC. 162 TABLE 170 BIO-RAD LABORATORIES, INC.: COMPANY OVERVIEW (2021) 162 FIGURE 29 BIO-RAD LABORATORIES, INC.: COMPANY SNAPSHOT (2021) 163 12.1.3 F. HOFFMAN-LA ROCHE LTD. 167 TABLE 171 F. HOFFMAN-LA ROCHE LTD: COMPANY OVERVIEW (2021) 167 FIGURE 30 F. HOFFMAN-LA ROCHE LTD: COMPANY SNAPSHOT (2021) 168 12.1.4 CAREDX, INC. 172 TABLE 172 CAREDX, INC.: COMPANY OVERVIEW (2021) 172 FIGURE 31 CAREDX, INC.: COMPANY SNAPSHOT (2021) 173 12.1.5 HOLOGIC, INC. 176 TABLE 173 HOLOGIC, INC.: COMPANY OVERVIEW (2021) 176 FIGURE 32 HOLOGIC, INC.: COMPANY SNAPSHOT (2021) 177 12.1.6 ILLUMINA, INC. 179 TABLE 174 ILLUMINA, INC.: COMPANY OVERVIEW (2021) 179 FIGURE 33 ILLUMINA, INC.: COMPANY SNAPSHOT (2021) 180 12.1.7 IMMUCOR, INC. 183 TABLE 175 IMMUCOR, INC.: COMPANY OVERVIEW (2021) 183 FIGURE 34 IMMUCOR, INC.: COMPANY SNAPSHOT (2021) 184 12.1.8 OMIXON INC. 188 TABLE 176 OMIXON INC.: COMPANY OVERVIEW (2021) 188 12.1.9 QIAGEN N.V. 190 TABLE 177 QIAGEN N.V.: COMPANY OVERVIEW (2021) 190 FIGURE 35 QIAGEN N.V.: COMPANY SNAPSHOT (2021) 191 12.1.10 TAKARA BIO INC. 197 TABLE 178 TAKARA BIO INC.: COMPANY OVERVIEW (2021) 197 FIGURE 36 TAKARA BIO, INC: COMPANY SNAPSHOT (2021) 197 12.1.11 THERMO FISHER SCIENTIFIC 199 TABLE 179 THERMO FISHER SCIENTIFIC: COMPANY OVERVIEW (2021) 199 FIGURE 37 THERMO FISHER SCIENTIFIC: COMPANY SNAPSHOT (2021) 200 12.1.12 BIOFORTUNA LIMITED 204 12.1.13 GENDX 205 TABLE 180 GENDX: COMPANY OVERVIEW (2021) 205 12.2 OTHER PLAYERS 207 12.2.1 FUJIREBIO 207 12.2.2 CREATIVE BIOLABS 207 12.2.3 ALPHA BIOTECH LIMITED 208 12.2.4 BAG DIAGNOSTICS GMBH 209 12.2.5 HANSA BIOPHARMA AB 210 12.2.6 HISTOGENETICS LLC 210 12.2.7 PACBIO 211 12.2.8 TBG DIAGNOSTICS LIMITED 212 12.2.9 INNO-TRAIN DIAGNOSTIK GMBH 212 12.2.10 KRISHGEN BIOSYSTEMS 213 *Details on Business Overview, Products Offered, Recent Developments, and MnM View (Key strengths/Right to Win, Strategic Choices Made, and Weaknesses and Competitive Threats) might not be captured in case of unlisted companies. 13 APPENDIX 214 13.1 DISCUSSION GUIDE 214 13.2 KNOWLEDGESTORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL 220 13.3 CUSTOMIZATION OPTIONS 222 13.4 RELATED REPORTS 222 13.5 AUTHOR DETAILS 223
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