体外毒物検査市場:製品(アッセイ(ウェスタンブロット、組織培養)、装置、消耗品、ソフトウェア)、毒性エンドポイント(ADME、皮膚刺激、細胞毒性)、技術、手法、産業(製薬、バイオテクノロジー)-2027年までの世界予測In Vitro Toxicology Testing Market by Product (Assays (Western Blot, Tissue Culture), Equipment, Consumables, Software), Toxicity Endpoints (ADME, Skin Irritation, Cytotoxicity), Technology, Method, Industry (Pharma,Biotech) - Global Forecast to 2027 体外毒物検査市場は、2022年の推定112億米ドルから、2027年にはCAGR10.8%で186億米ドルに達すると予測されます。技術的な進歩や、医薬品開発の初期段階で毒性を検出するための研究開発費の増加などが、市場を牽... もっと見る
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サマリー体外毒物検査市場は、2022年の推定112億米ドルから、2027年にはCAGR10.8%で186億米ドルに達すると予測されます。技術的な進歩や、医薬品開発の初期段階で毒性を検出するための研究開発費の増加などが、市場を牽引する要因となっています。"2021年にはADMEセグメントが最大の市場シェアを占めると予想される。" in vitro毒性試験市場は、あらゆる産業で実施される毒性エンドポイントや試験に基づいて、遺伝毒性、細胞毒性、ADME、皮膚刺激・腐食・感作、眼毒性、器官毒性、光毒性、皮膚毒性、その他のエンドポイント&試験に区分されます。2021年のin vitro毒性試験市場では、ADME分野が最大のシェアを占めています。 "予測期間中は、ソフトウェア分野が最も高い成長率を示すと予想される。" 製品およびサービスに基づいて、in vitro毒性試験市場は、消耗品、アッセイ、機器、ソフトウェア、およびサービスに区分されます。産業界におけるソフトウェア使用の増加により、ソフトウェア分野は予測期間中にin vitro toxicology testing市場で最も高い成長を見せると予測されます。 "予測期間中、トキシコゲノミクスは最も高い成長率を示すと予想される" 予測期間中、ゲノミクスとプロテオミクスの分野で起こっている技術的進歩により、トキシコゲノミクスセグメントは最も高いCAGRで成長すると予測されています。 "2021年、欧州はin vitro毒物検査市場で活動するプレーヤーにとって最大のシェアを占めると予想されます。" 2021年、欧州はin vitro毒物検査市場で最大のシェアを占めています。同地域の化学および化粧品産業におけるin vitro毒性試験アッセイおよびサービスの高い採用率などの要因が、同市場の成長に寄与すると予想される主な理由である。 本レポートで参照した主な参加企業の内訳は以下のとおりです。 - 企業タイプ別Tier 1 (35%)、Tier 2 (45%)、Tier 3 (20%) - 役職別Cレベル(35%)、ディレクターレベル(25%)、その他(40%) - 地域別北米(45%)、欧州(30%)、アジア太平洋(20%)、中南米(3%)、中近東・アフリカ(2) インビト毒物検査市場の主要企業 インビトロ毒性試験市場の有力プレイヤーは、Thermo Fisher Scientific Inc.(米国)、Laboratory Corporation of America Holdings(米国)、Bio-Rad Laboratories, Inc.(米国)、General Electric Company(米国)、Eurofins Scientific(Luxembourg)、Merck KGaA(ドイツ)、Charles River Laboratories International, Inc.(米国)、Catalent, Inc.(米国)、Evotec(英国)、SGS S.A.(スイス)、QIAGEN(ドイツ)、Promega Corporation(米国)、Gentronix Limited(英国)、BioIVT(米国)、MB Research Laboratories(米国) ,Creative Biolabs(米国), GVK Biosciences Private Limited(インド), Shanghai Medicon Inc(中国), Creative Biorray(米国)および Insphero(スイス)です。 調査対象 本レポートは、世界のin vitro毒性試験市場の市場規模および今後の成長可能性を、製品&サービス、技術、毒性エンドポイント&試験、産業、手法、地域セグメント別に推計することを目的としています。また、同市場の主要企業の詳細な競合分析、企業プロファイル、製品提供、最近の開発状況も掲載しています。 本レポートを購入する理由 本レポートは、既存企業だけでなく、新規参入企業や中小企業も市場の脈拍を測ることができ、ひいてはより大きなシェアを獲得するのに役立つことでしょう。本レポートを購入された企業は、以下の5つの戦略を組み合わせることで、市場での存在感を高めることができます。 本レポートでは、以下のポイントについて考察しています。 - 市場浸透。体外毒物検査の世界市場における上位企業が提供する製品ポートフォリオに関する包括的な情報 - 製品開発/イノベーション。体外毒物検査の世界市場における今後の動向、研究開発活動、製品発売に関する詳細な洞察 - 市場開発。有利な新興地域に関する包括的な情報 - 市場の多様化。新製品、成長地域、体外毒物検査の世界市場の最新動向に関する徹底的な情報提供 - 競争力のある評価。体外毒物検査の世界市場における主要企業の市場ランキング、成長戦略、収益分析、サービスに関する詳細な評価 目次1 INTRODUCTION 441.1 STUDY OBJECTIVES 44 1.2 MARKET DEFINITION 44 1.2.1 INCLUSIONS AND EXCLUSIONS 44 1.2.2 MARKETS COVERED 45 FIGURE 1 IN VITRO TOXICOLOGY TESTING MARKET 45 FIGURE 2 IN VITRO TOXICOLOGY TESTING MARKET: GEOGRAPHIC SCOPE 46 1.2.3 YEARS CONSIDERED FOR STUDY 46 1.3 CURRENCY 47 1.4 STAKEHOLDERS 47 1.5 LIMITATIONS 47 1.6 SUMMARY OF CHANGES 47 2 RESEARCH METHODOLOGY 49 2.1 RESEARCH APPROACH 49 FIGURE 3 RESEARCH DESIGN 49 2.1.1 SECONDARY RESEARCH 49 2.1.1.1 Key data from secondary sources 50 2.1.2 PRIMARY RESEARCH 51 2.1.2.1 Key data from primary sources 51 2.1.2.2 Breakdown of primaries 52 FIGURE 4 BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY TYPE, DESIGNATION, AND REGION 52 2.2 MARKET SIZE ESTIMATION & VALIDATION APPROACH 52 FIGURE 5 MARKET SIZE APPROACH 54 FIGURE 6 BOTTOM-UP APPROACH 54 2.3 DATA TRIANGULATION APPROACH 55 FIGURE 7 DATA TRIANGULATION METHODOLOGY 55 2.4 MARKET SHARE ESTIMATION 56 2.5 ASSUMPTIONS FOR STUDY 56 3 EXECUTIVE SUMMARY 57 FIGURE 8 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022 VS. 2027 (USD MILLION) 57 FIGURE 9 IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2022 VS. 2027 (USD MILLION) 58 FIGURE 10 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022 VS. 2027 (USD MILLION) 59 FIGURE 11 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022 VS. 2027 (USD MILLION) 59 FIGURE 12 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022 VS. 2027 (USD MILLION) 60 FIGURE 13 GEOGRAPHIC ANALYSIS: IN VITRO TOXICOLOGY TESTING MARKET 61 4 PREMIUM INSIGHTS 62 4.1 IN VITRO TOXICOLOGY TESTING MARKET OVERVIEW 62 FIGURE 14 OPPOSITION TO ANIMAL TESTING IS MAJOR FACTOR DRIVING MARKET GROWTH 62 4.2 ASIA PACIFIC: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD 63 FIGURE 15 CELLULAR ASSAYS HELD LARGEST SHARE OF IN VITRO TOXICOLOGY TESTING MARKET IN ASIA PACIFIC IN 2021 63 4.3 IN VITRO TOXICOLOGY TESTING MARKET: GEOGRAPHIC GROWTH OPPORTUNITIES 64 FIGURE 16 CHINA IS LIKELY TO BE FASTEST-GROWING MARKET IN GLOBAL IN VITRO TOXICOLOGY TESTING MARKET DURING FORECAST PERIOD 64 4.4 IN VITRO TOXICOLOGY TESTING MARKET, BY REGION 65 FIGURE 17 EUROPE WILL CONTINUE TO DOMINATE IN VITRO TOXICOLOGY TESTING MARKET IN 2027 65 4.5 IN VITRO TOXICOLOGY TESTING MARKET: DEVELOPED VS. DEVELOPING MARKETS 65 FIGURE 18 DEVELOPING MARKETS TO REGISTER HIGHER CAGR THAN DEVELOPED MARKETS THROUGHOUT FORECAST PERIOD 65 5 MARKET OVERVIEW 66 5.1 INTRODUCTION 66 5.2 MARKET DYNAMICS 66 FIGURE 19 IN VITRO TOXICOLOGY TESTING MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 66 5.2.1 MARKET DRIVERS 67 5.2.1.1 Public opposition to animal testing 67 5.2.1.2 Technological advancements in toxicology 67 5.2.1.3 R&D on early-stage toxicity detection 68 5.2.2 MARKET RESTRAINTS 68 5.2.2.1 Reluctance of some regulatory authorities to adopt alternative toxicology testing methods 68 5.2.2.2 Failure to establish intricacies of in-vivo conditions 69 5.2.2.3 Lack of in vitro models to study complex endpoints 69 5.2.3 MARKET OPPORTUNITIES 69 5.2.3.1 Growing focus on drug discovery and personalized medicine using in vitro methods 69 5.2.3.2 Increasing number of toxicology databases 70 5.2.4 MARKET CHALLENGES 71 5.2.4.1 Dearth of skilled professionals in toxicity testing 71 6 INDUSTRY INSIGHTS 72 6.1 INTRODUCTION 72 6.2 INDUSTRY TRENDS 72 6.2.1 INCREASING FOCUS ON PREDICTIVE TOXICOLOGY 72 6.3 SUPPLY CHAIN ANALYSIS 73 FIGURE 20 SUPPLY CHAIN ANALYSIS: IN VITRO TOXICOLOGY TESTING MARKET 73 6.4 REGULATORY COMMITTEE ACTIVITIES 73 6.4.1 MAJOR STAKEHOLDERS 74 6.4.2 KEY INFLUENCERS 74 6.5 COVID-19 IMPACT ON IN VITRO TOXICOLOGY MARKET 75 FIGURE 21 IMPACT OF COVID-19 ON IN VITRO TOXICOLOGY TESTING MARKET 76 6.6 PORTER’S FIVE FORCES ANALYSIS 76 TABLE 1 PORTER’S FIVE FORCES ANALYSIS 76 6.6.1 THREAT OF NEW ENTRANTS 77 6.6.2 THREAT OF SUBSTITUTES 77 6.6.3 BARGAINING POWER OF SUPPLIERS 77 6.6.4 DEGREE OF COMPETITIVE RIVALRY 77 6.7 TECHNOLOGY ANALYSIS 77 7 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE 79 7.1 INTRODUCTION 80 7.2 COVID-19 IMPACT, BY PRODUCT & SERVICE 80 FIGURE 22 CONSUMABLES TO CAPTURE MAJORITY OF MARKET SHARE IN 2022 80 TABLE 2 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 81 TABLE 3 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 81 7.3 CONSUMABLES 82 7.3.1 CONSUMABLES TO ACCOUNT FOR LARGER MARKET SHARE THAN OTHER PRODUCTS IN 2022 82 TABLE 4 IN VITRO TOXICOLOGY TESTING CONSUMABLES MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 83 TABLE 5 IN VITRO TOXICOLOGY TESTING CONSUMABLES MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 84 7.4 ASSAYS 84 TABLE 6 ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY TYPE, 2019–2021 (USD MILLION) 85 TABLE 7 ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY TYPE, 2022–2027 (USD MILLION) 85 TABLE 8 ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 86 TABLE 9 ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 86 7.4.1 BACTERIAL TOXICITY ASSAYS 87 7.4.1.1 Bacterial assays to capture largest market share in coming years owing to their increasing adoption across several industries 87 TABLE 10 BACTERIAL TOXICITY ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 87 TABLE 11 BACTERIAL TOXICITY ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 88 7.4.2 ENZYME TOXICITY ASSAYS 88 7.4.2.1 Enzyme toxicity assays are increasingly used in endocrine-disrupting studies—major factor driving market growth 88 TABLE 12 ENZYME TOXICITY ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 89 TABLE 13 ENZYME TOXICITY ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 89 7.4.3 CELL-BASED ELISA & WESTERN BLOTS 90 7.4.3.1 Cell-based assays are cost-effective, thereby witnessing increasing adoption in drug discovery 90 TABLE 14 CELL-BASED ELISA & WESTERN BLOTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 91 TABLE 15 CELL-BASED ELISA & WESTERN BLOTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 91 7.4.4 RECEPTOR-BINDING ASSAYS 92 7.4.4.1 Receptor-binding assays are suitable for high-throughput formats, thereby exhibiting accelerated demand 92 TABLE 16 RECEPTOR-BINDING ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 92 TABLE 17 RECEPTOR-BINDING ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 93 7.4.5 TISSUE CULTURE ASSAYS 93 7.4.5.1 Tissue culture assays can mimic in-vivo tissue architecture, thereby attracting researchers 93 TABLE 18 TISSUE CULTURE ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 94 TABLE 19 TISSUE CULTURE ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 94 7.4.6 OTHER ASSAYS 95 TABLE 20 OTHER ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 95 TABLE 21 OTHER ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 96 7.5 EQUIPMENT 96 7.5.1 FULLY AUTOMATED IN VITRO TOXICOLOGY EQUIPMENT ARE INCREASINGLY ADOPTED IN RESEARCH 96 TABLE 22 EQUIPMENT: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 97 TABLE 23 EQUIPMENT: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 98 7.6 SOFTWARE 98 7.6.1 SOFTWARE SOLUTIONS ARE VITAL IN REDUCING ANALYSIS TIME AND MANAGING LARGE VOLUMES OF DATA GENERATED DURING OPERATIONS 98 TABLE 24 SOFTWARE: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 99 TABLE 25 SOFTWARE: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 100 7.7 SERVICES 100 7.7.1 LACK OF INFRASTRUCTURE AND EXPERTISE HAVE DRIVEN RELIANCE ON SERVICE PROVIDERS 100 TABLE 26 SERVICES: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 101 TABLE 27 SERVICES: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 102 8 IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST 103 8.1 INTRODUCTION 104 FIGURE 23 ORGAN TOXICITY TESTING TO REGISTER HIGHEST CAGR DURING FORECAST PERIOD 104 TABLE 28 IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2019–2021 (USD MILLION) 105 TABLE 29 IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2022–2027 (USD MILLION) 105 8.2 ADME (ABSORPTION, DISTRIBUTION, METABOLISM, & EXCRETION) 106 8.2.1 ADME TESTING TO COMMAND IN VITRO TOXICOLOGY TESTING MARKET DURING FORECAST PERIOD 106 TABLE 30 ADME: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 107 TABLE 31 ADME: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 107 8.3 SKIN IRRITATION, CORROSION, & SENSITIZATION 108 8.3.1 SKIN IRRITATION, CORROSION, & SENSITIZATION ARE MAJOR ENDPOINTS STUDIED IN COSMETICS INDUSTRY 108 TABLE 32 SKIN IRRITATION, CORROSION, & SENSITIZATION: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 109 TABLE 33 SKIN IRRITATION, CORROSION, & SENSITIZATION: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 109 8.4 GENOTOXICITY 110 8.4.1 REGULATORY AUTHORITIES REVIEW AND VALIDATE HIGHER NUMBER OF GENOTOXICITY TESTS THAN ANY OTHER ENDPOINT, THEREBY PROPELLING MARKET GROWTH 110 TABLE 34 GENOTOXICITY: IN VITRO TOXICOLOGY TESTING, BY GEOGRAPHY, 2019–2021 (USD MILLION) 111 TABLE 35 GENOTOXICITY: IN VITRO TOXICOLOGY TESTING, BY GEOGRAPHY, 2022–2027 (USD MILLION) 111 8.5 CYTOTOXICITY 112 8.5.1 RISING NEED FOR BIOSAFETY LARGELY CONTRIBUTES TO GROWTH OF CYTOTOXICITY TESTING MARKET 112 TABLE 36 CYTOTOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 113 TABLE 37 CYTOTOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 113 8.6 OCULAR TOXICITY TESTING 114 8.6.1 IN VITRO AND EX-VIVO METHODS ARE GAINING HIGH RECOGNITION FOR OCULAR TOXICITY TESTING 114 TABLE 38 OCULAR TOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 114 TABLE 39 OCULAR TOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 115 8.7 ORGAN TOXICITY 115 8.7.1 HIGH-CONTENT SCREENING AND CELL-BASED ASSAYS ARE USED TO DETECT ORGAN-SPECIFIC TOXICITY 115 TABLE 40 ORGAN TOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 116 TABLE 41 ORGAN TOXICITY: TE IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 117 8.8 PHOTOTOXICITY 117 8.8.1 VALIDATED NON-ANIMAL METHODS ARE USED TO EVALUATE PHOTO SAFETY OF COSMETICS, PHARMACEUTICALS, & CHEMICALS 117 TABLE 42 PHOTOTOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 118 TABLE 43 PHOTOTOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 119 8.9 DERMAL TOXICITY 119 8.9.1 IN VITRO METHODS FOR DERMAL TOXICITY TESTING ARE EXPECTED TO GAIN RECOGNITION IN COMING YEARS 119 TABLE 44 DERMAL TOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 120 TABLE 45 DERMAL TOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 121 8.10 OTHER ENDPOINTS & TESTS 121 TABLE 46 OTHER ENDPOINTS & TESTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 122 TABLE 47 OTHER ENDPOINTS & TESTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 122 9 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY 123 9.1 INTRODUCTION 124 FIGURE 24 TOXICOGENOMICS SEGMENT TO EXHIBIT HIGHEST CAGR IN IN VITRO TOXICOLOGY TESTING MARKET DURING FORECAST PERIOD 124 TABLE 48 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 124 TABLE 49 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 125 9.2 CELL CULTURE 125 9.2.1 CELL- & TISSUE-BASED TECHNOLOGIES ARE WIDELY ADOPTED IN IN VITRO TESTING 125 TABLE 50 CELL CULTURE: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 126 TABLE 51 CELL CULTURE: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 126 9.3 HIGH-THROUGHPUT 127 9.3.1 INCREASING USE OF HIGH-CONTENT IMAGING TECHNOLOGIES IN TOXICITY TESTING BOOSTS MARKET GROWTH 127 TABLE 52 HIGH-THROUGHPUT: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 128 TABLE 53 HIGH-THROUGHPUT: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 128 9.4 TOXICOGENOMICS 129 9.4.1 IMPROVEMENTS IN PROTEOMIC TECHNOLOGIES ENHANCE STUDY OF GENES & PROTEIN ACTIVITIES DURING TOXICITY ANALYSIS 129 TABLE 54 TOXICOGENOMICS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 129 TABLE 55 TOXICOGENOMICS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 130 10 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY 131 10.1 INTRODUCTION 132 FIGURE 25 PHARMACEUTICALS & BIOPHARMACEUTICALS INDUSTRY TO HOLD LARGEST MARKET SHARE THROUGHOUT FORECAST PERIOD 132 TABLE 56 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 132 TABLE 57 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 133 10.2 COVID-19 IMPACT, BY INDUSTRY 133 10.3 PHARMACEUTICALS & BIOPHARMACEUTICALS 133 10.3.1 DRUG ATTRITION RATE LEADS TO HIGH ADOPTION OF IN VITRO TESTING ASSAYS IN EARLY STAGES OF DRUG DEVELOPMENT 133 TABLE 58 PHARMACEUTICALS & BIOPHARMACEUTICALS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 135 TABLE 59 PHARMACEUTICALS & BIOPHARMACEUTICALS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 136 10.4 COSMETICS & HOUSEHOLD PRODUCTS 136 10.4.1 BAN ON ANIMAL TESTING LEADING TO ADOPTION OF IN VITRO ASSAYS FOR SAFETY TESTING 136 TABLE 60 COSMETICS & HOUSEHOLD PRODUCTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 137 TABLE 61 COSMETICS & HOUSEHOLD PRODUCTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 138 10.5 FOOD 138 10.5.1 INCREASING FOCUS ON FOOD SAFETY DRIVES REQUIREMENT FOR IN VITRO TOXICOLOGY TESTING PRODUCTS 138 TABLE 62 TYPES OF TOXICOLOGY TESTS IN FOOD 139 TABLE 63 FOOD: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 140 TABLE 64 FOOD: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 141 10.6 CHEMICALS 141 10.6.1 INCREASING FOCUS ON ORGANOID-BASED IN VITRO APPROACHES FOR CHEMICALS TESTING PROPELS MARKET GROWTH 141 TABLE 65 CHEMICALS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 142 TABLE 66 CHEMICALS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 143 11 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD 144 11.1 INTRODUCTION 145 FIGURE 26 IN-SILICO MODELS TO RECORD HIGHEST CAGR IN IN VITRO TOXICOLOGY TESTING MARKET DURING FORECAST PERIOD 145 TABLE 67 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 145 TABLE 68 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 146 11.2 CELLULAR ASSAYS 146 11.2.1 DEVELOPMENT OF MULTI-PARAMETER ASSAYS WILL PROVIDE SIGNIFICANT GROWTH OPPORTUNITIES TO MARKET PLAYERS 146 TABLE 69 CELLULAR ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 147 TABLE 70 CELLULAR ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 148 11.3 BIOCHEMICAL ASSAYS 148 11.3.1 BIOCHEMICAL ASSAYS ARE ADOPTED AT HIGHER RATE IN PHARMACEUTICALS INDUSTRY THAN CHEMICALS AND FOOD INDUSTRIES 148 TABLE 71 BIOCHEMICAL ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 149 TABLE 72 BIOCHEMICAL ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 150 11.4 IN-SILICO MODELS 150 11.4.1 IN-SILICO MODELS ARE EXPECTED TO WITNESS HIGHEST CAGR FROM 2022 TO 2027 150 TABLE 73 IN-SILICO MODELS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 151 TABLE 74 IN-SILICO MODELS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 152 11.5 EX-VIVO MODELS 152 11.5.1 EX-VIVO MODELS ARE WIDELY USED IN SKIN AND EYE TOXICOLOGY TESTING IN COSMETICS INDUSTRY 152 TABLE 75 EX-VIVO MODELS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 153 TABLE 76 EX-VIVO MODELS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 154 12 IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHIC ANALYSIS 155 12.1 INTRODUCTION 156 12.2 COVID-19 IMPACT, BY REGION 156 FIGURE 27 IN VITRO TOXICOLOGY TESTING MARKET: GEOGRAPHIC SNAPSHOT 157 TABLE 77 IN VITRO TOXICOLOGY TESTING MARKET, BY REGION, 2019–2021 (USD MILLION) 157 TABLE 78 IN VITRO TOXICOLOGY TESTING MARKET, BY REGION, 2022–2027 (USD MILLION) 158 12.3 EUROPE 158 FIGURE 28 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET SNAPSHOT 159 TABLE 79 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY, 2019–2021 (USD MILLION) 160 TABLE 80 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY, 2022–2027 (USD MILLION) 160 TABLE 81 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 161 TABLE 82 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 161 TABLE 83 EUROPE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 162 TABLE 84 EUROPE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 162 TABLE 85 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 163 TABLE 86 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 163 TABLE 87 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 164 TABLE 88 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 164 TABLE 89 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 164 TABLE 90 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 165 TABLE 91 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 165 TABLE 92 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 165 12.3.1 GERMANY 166 12.3.1.1 Germany holds the largest share of the European market 166 TABLE 93 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 167 TABLE 94 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 167 TABLE 95 GERMANY: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 168 TABLE 96 GERMANY: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 168 TABLE 97 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 169 TABLE 98 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 169 TABLE 99 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 170 TABLE 100 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 170 TABLE 101 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 170 TABLE 102 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 171 TABLE 103 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 171 TABLE 104 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 171 12.3.2 UK 172 12.3.2.1 Rising awareness, growing R&D, and increasing collaborations for In Vitro Toxicology Testing Market are key indicators of market growth in UK 172 TABLE 105 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 173 TABLE 106 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 173 TABLE 107 UK: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 174 TABLE 108 UK: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022-2027 (USD MILLION) 174 TABLE 109 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 175 TABLE 110 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 175 TABLE 111 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 176 TABLE 112 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 176 TABLE 113 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 176 TABLE 114 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 177 TABLE 115 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 177 TABLE 116 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 177 12.3.3 FRANCE 178 12.3.3.1 Proteomics research initiatives supported by government aid market growth in France 178 TABLE 117 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 179 TABLE 118 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 179 TABLE 119 FRANCE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 180 TABLE 120 FRANCE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 180 TABLE 121 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 181 TABLE 122 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 181 TABLE 123 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 182 TABLE 124 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 182 TABLE 125 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 182 TABLE 126 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 183 TABLE 127 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 183 TABLE 128 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 183 12.3.4 ITALY 184 12.3.4.1 Italian market growth is mainly driven by increased volume of life sciences research 184 TABLE 129 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 184 TABLE 130 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 185 TABLE 131 ITALY: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 185 TABLE 132 ITALY: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 186 TABLE 133 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 186 TABLE 134 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 187 TABLE 135 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 187 TABLE 136 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 188 TABLE 137 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 188 TABLE 138 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 188 TABLE 139 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 189 TABLE 140 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 189 12.3.5 SPAIN 189 12.3.5.1 Spain’s growing Chemicals industry stimulates in vitro toxicology testing market growth 189 TABLE 141 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 190 TABLE 142 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 190 TABLE 143 SPAIN: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 191 TABLE 144 SPAIN: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 191 TABLE 145 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 192 TABLE 146 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 192 TABLE 147 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 193 TABLE 148 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 193 TABLE 149 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 193 TABLE 150 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 194 TABLE 151 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 194 TABLE 152 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 194 12.3.6 REST OF EUROPE 195 TABLE 153 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 196 TABLE 154 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 196 TABLE 155 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 196 TABLE 156 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 197 TABLE 157 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 197 TABLE 158 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 198 TABLE 159 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 198 TABLE 160 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 199 TABLE 161 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 199 TABLE 162 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 199 TABLE 163 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 200 TABLE 164 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 200 12.4 NORTH AMERICA 201 FIGURE 29 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET SNAPSHOT 202 TABLE 165 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY, 2019–2021 (USD MILLION) 202 TABLE 166 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY, 2022–2027 (USD MILLION) 203 TABLE 167 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 203 TABLE 168 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 203 TABLE 169 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 204 TABLE 170 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 204 TABLE 171 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 205 TABLE 172 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 205 TABLE 173 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 206 TABLE 174 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 206 TABLE 175 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 206 TABLE 176 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 207 TABLE 177 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 207 TABLE 178 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 207 12.4.1 US 208 12.4.1.1 US dominates North American market due to growing focus on biomarker discovery and research in structure-based drug design 208 TABLE 179 US: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 209 TABLE 180 US: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 209 TABLE 181 US: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 210 TABLE 182 US: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 210 TABLE 183 US: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 211 TABLE 184 US: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 211 TABLE 185 US: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 212 TABLE 186 US: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 212 TABLE 187 US: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 212 TABLE 188 US: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 213 TABLE 189 US: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 213 TABLE 190 US: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 213 12.4.2 CANADA 214 12.4.2.1 Strong support to carry out R&D in pharmaceutical and proteomics fields fosters market growth in Canada 214 TABLE 191 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 215 TABLE 192 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 215 TABLE 193 CANADA: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 216 TABLE 194 CANADA: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 216 TABLE 195 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 217 TABLE 196 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 217 TABLE 197 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 218 TABLE 198 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 218 TABLE 199 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 218 TABLE 200 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 219 TABLE 201 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 219 TABLE 202 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 219
SummaryThe in vitro toxicology testing market is expected to reach USD 18.6 billion by 2027 from an estimated USD 11.2 billion in 2022, at a CAGR of 10.8%. Factors such as, technological advancements, and increasing R&D expenditure to detect toxicity at an early stage during drug development are the factors to drive the market Table of Contents1 INTRODUCTION 441.1 STUDY OBJECTIVES 44 1.2 MARKET DEFINITION 44 1.2.1 INCLUSIONS AND EXCLUSIONS 44 1.2.2 MARKETS COVERED 45 FIGURE 1 IN VITRO TOXICOLOGY TESTING MARKET 45 FIGURE 2 IN VITRO TOXICOLOGY TESTING MARKET: GEOGRAPHIC SCOPE 46 1.2.3 YEARS CONSIDERED FOR STUDY 46 1.3 CURRENCY 47 1.4 STAKEHOLDERS 47 1.5 LIMITATIONS 47 1.6 SUMMARY OF CHANGES 47 2 RESEARCH METHODOLOGY 49 2.1 RESEARCH APPROACH 49 FIGURE 3 RESEARCH DESIGN 49 2.1.1 SECONDARY RESEARCH 49 2.1.1.1 Key data from secondary sources 50 2.1.2 PRIMARY RESEARCH 51 2.1.2.1 Key data from primary sources 51 2.1.2.2 Breakdown of primaries 52 FIGURE 4 BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY TYPE, DESIGNATION, AND REGION 52 2.2 MARKET SIZE ESTIMATION & VALIDATION APPROACH 52 FIGURE 5 MARKET SIZE APPROACH 54 FIGURE 6 BOTTOM-UP APPROACH 54 2.3 DATA TRIANGULATION APPROACH 55 FIGURE 7 DATA TRIANGULATION METHODOLOGY 55 2.4 MARKET SHARE ESTIMATION 56 2.5 ASSUMPTIONS FOR STUDY 56 3 EXECUTIVE SUMMARY 57 FIGURE 8 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022 VS. 2027 (USD MILLION) 57 FIGURE 9 IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2022 VS. 2027 (USD MILLION) 58 FIGURE 10 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022 VS. 2027 (USD MILLION) 59 FIGURE 11 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022 VS. 2027 (USD MILLION) 59 FIGURE 12 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022 VS. 2027 (USD MILLION) 60 FIGURE 13 GEOGRAPHIC ANALYSIS: IN VITRO TOXICOLOGY TESTING MARKET 61 4 PREMIUM INSIGHTS 62 4.1 IN VITRO TOXICOLOGY TESTING MARKET OVERVIEW 62 FIGURE 14 OPPOSITION TO ANIMAL TESTING IS MAJOR FACTOR DRIVING MARKET GROWTH 62 4.2 ASIA PACIFIC: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD 63 FIGURE 15 CELLULAR ASSAYS HELD LARGEST SHARE OF IN VITRO TOXICOLOGY TESTING MARKET IN ASIA PACIFIC IN 2021 63 4.3 IN VITRO TOXICOLOGY TESTING MARKET: GEOGRAPHIC GROWTH OPPORTUNITIES 64 FIGURE 16 CHINA IS LIKELY TO BE FASTEST-GROWING MARKET IN GLOBAL IN VITRO TOXICOLOGY TESTING MARKET DURING FORECAST PERIOD 64 4.4 IN VITRO TOXICOLOGY TESTING MARKET, BY REGION 65 FIGURE 17 EUROPE WILL CONTINUE TO DOMINATE IN VITRO TOXICOLOGY TESTING MARKET IN 2027 65 4.5 IN VITRO TOXICOLOGY TESTING MARKET: DEVELOPED VS. DEVELOPING MARKETS 65 FIGURE 18 DEVELOPING MARKETS TO REGISTER HIGHER CAGR THAN DEVELOPED MARKETS THROUGHOUT FORECAST PERIOD 65 5 MARKET OVERVIEW 66 5.1 INTRODUCTION 66 5.2 MARKET DYNAMICS 66 FIGURE 19 IN VITRO TOXICOLOGY TESTING MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 66 5.2.1 MARKET DRIVERS 67 5.2.1.1 Public opposition to animal testing 67 5.2.1.2 Technological advancements in toxicology 67 5.2.1.3 R&D on early-stage toxicity detection 68 5.2.2 MARKET RESTRAINTS 68 5.2.2.1 Reluctance of some regulatory authorities to adopt alternative toxicology testing methods 68 5.2.2.2 Failure to establish intricacies of in-vivo conditions 69 5.2.2.3 Lack of in vitro models to study complex endpoints 69 5.2.3 MARKET OPPORTUNITIES 69 5.2.3.1 Growing focus on drug discovery and personalized medicine using in vitro methods 69 5.2.3.2 Increasing number of toxicology databases 70 5.2.4 MARKET CHALLENGES 71 5.2.4.1 Dearth of skilled professionals in toxicity testing 71 6 INDUSTRY INSIGHTS 72 6.1 INTRODUCTION 72 6.2 INDUSTRY TRENDS 72 6.2.1 INCREASING FOCUS ON PREDICTIVE TOXICOLOGY 72 6.3 SUPPLY CHAIN ANALYSIS 73 FIGURE 20 SUPPLY CHAIN ANALYSIS: IN VITRO TOXICOLOGY TESTING MARKET 73 6.4 REGULATORY COMMITTEE ACTIVITIES 73 6.4.1 MAJOR STAKEHOLDERS 74 6.4.2 KEY INFLUENCERS 74 6.5 COVID-19 IMPACT ON IN VITRO TOXICOLOGY MARKET 75 FIGURE 21 IMPACT OF COVID-19 ON IN VITRO TOXICOLOGY TESTING MARKET 76 6.6 PORTER’S FIVE FORCES ANALYSIS 76 TABLE 1 PORTER’S FIVE FORCES ANALYSIS 76 6.6.1 THREAT OF NEW ENTRANTS 77 6.6.2 THREAT OF SUBSTITUTES 77 6.6.3 BARGAINING POWER OF SUPPLIERS 77 6.6.4 DEGREE OF COMPETITIVE RIVALRY 77 6.7 TECHNOLOGY ANALYSIS 77 7 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE 79 7.1 INTRODUCTION 80 7.2 COVID-19 IMPACT, BY PRODUCT & SERVICE 80 FIGURE 22 CONSUMABLES TO CAPTURE MAJORITY OF MARKET SHARE IN 2022 80 TABLE 2 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 81 TABLE 3 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 81 7.3 CONSUMABLES 82 7.3.1 CONSUMABLES TO ACCOUNT FOR LARGER MARKET SHARE THAN OTHER PRODUCTS IN 2022 82 TABLE 4 IN VITRO TOXICOLOGY TESTING CONSUMABLES MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 83 TABLE 5 IN VITRO TOXICOLOGY TESTING CONSUMABLES MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 84 7.4 ASSAYS 84 TABLE 6 ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY TYPE, 2019–2021 (USD MILLION) 85 TABLE 7 ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY TYPE, 2022–2027 (USD MILLION) 85 TABLE 8 ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 86 TABLE 9 ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 86 7.4.1 BACTERIAL TOXICITY ASSAYS 87 7.4.1.1 Bacterial assays to capture largest market share in coming years owing to their increasing adoption across several industries 87 TABLE 10 BACTERIAL TOXICITY ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 87 TABLE 11 BACTERIAL TOXICITY ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 88 7.4.2 ENZYME TOXICITY ASSAYS 88 7.4.2.1 Enzyme toxicity assays are increasingly used in endocrine-disrupting studies—major factor driving market growth 88 TABLE 12 ENZYME TOXICITY ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 89 TABLE 13 ENZYME TOXICITY ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 89 7.4.3 CELL-BASED ELISA & WESTERN BLOTS 90 7.4.3.1 Cell-based assays are cost-effective, thereby witnessing increasing adoption in drug discovery 90 TABLE 14 CELL-BASED ELISA & WESTERN BLOTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 91 TABLE 15 CELL-BASED ELISA & WESTERN BLOTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 91 7.4.4 RECEPTOR-BINDING ASSAYS 92 7.4.4.1 Receptor-binding assays are suitable for high-throughput formats, thereby exhibiting accelerated demand 92 TABLE 16 RECEPTOR-BINDING ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 92 TABLE 17 RECEPTOR-BINDING ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 93 7.4.5 TISSUE CULTURE ASSAYS 93 7.4.5.1 Tissue culture assays can mimic in-vivo tissue architecture, thereby attracting researchers 93 TABLE 18 TISSUE CULTURE ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 94 TABLE 19 TISSUE CULTURE ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 94 7.4.6 OTHER ASSAYS 95 TABLE 20 OTHER ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 95 TABLE 21 OTHER ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 96 7.5 EQUIPMENT 96 7.5.1 FULLY AUTOMATED IN VITRO TOXICOLOGY EQUIPMENT ARE INCREASINGLY ADOPTED IN RESEARCH 96 TABLE 22 EQUIPMENT: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 97 TABLE 23 EQUIPMENT: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 98 7.6 SOFTWARE 98 7.6.1 SOFTWARE SOLUTIONS ARE VITAL IN REDUCING ANALYSIS TIME AND MANAGING LARGE VOLUMES OF DATA GENERATED DURING OPERATIONS 98 TABLE 24 SOFTWARE: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 99 TABLE 25 SOFTWARE: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 100 7.7 SERVICES 100 7.7.1 LACK OF INFRASTRUCTURE AND EXPERTISE HAVE DRIVEN RELIANCE ON SERVICE PROVIDERS 100 TABLE 26 SERVICES: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 101 TABLE 27 SERVICES: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 102 8 IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST 103 8.1 INTRODUCTION 104 FIGURE 23 ORGAN TOXICITY TESTING TO REGISTER HIGHEST CAGR DURING FORECAST PERIOD 104 TABLE 28 IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2019–2021 (USD MILLION) 105 TABLE 29 IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2022–2027 (USD MILLION) 105 8.2 ADME (ABSORPTION, DISTRIBUTION, METABOLISM, & EXCRETION) 106 8.2.1 ADME TESTING TO COMMAND IN VITRO TOXICOLOGY TESTING MARKET DURING FORECAST PERIOD 106 TABLE 30 ADME: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 107 TABLE 31 ADME: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 107 8.3 SKIN IRRITATION, CORROSION, & SENSITIZATION 108 8.3.1 SKIN IRRITATION, CORROSION, & SENSITIZATION ARE MAJOR ENDPOINTS STUDIED IN COSMETICS INDUSTRY 108 TABLE 32 SKIN IRRITATION, CORROSION, & SENSITIZATION: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 109 TABLE 33 SKIN IRRITATION, CORROSION, & SENSITIZATION: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 109 8.4 GENOTOXICITY 110 8.4.1 REGULATORY AUTHORITIES REVIEW AND VALIDATE HIGHER NUMBER OF GENOTOXICITY TESTS THAN ANY OTHER ENDPOINT, THEREBY PROPELLING MARKET GROWTH 110 TABLE 34 GENOTOXICITY: IN VITRO TOXICOLOGY TESTING, BY GEOGRAPHY, 2019–2021 (USD MILLION) 111 TABLE 35 GENOTOXICITY: IN VITRO TOXICOLOGY TESTING, BY GEOGRAPHY, 2022–2027 (USD MILLION) 111 8.5 CYTOTOXICITY 112 8.5.1 RISING NEED FOR BIOSAFETY LARGELY CONTRIBUTES TO GROWTH OF CYTOTOXICITY TESTING MARKET 112 TABLE 36 CYTOTOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 113 TABLE 37 CYTOTOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 113 8.6 OCULAR TOXICITY TESTING 114 8.6.1 IN VITRO AND EX-VIVO METHODS ARE GAINING HIGH RECOGNITION FOR OCULAR TOXICITY TESTING 114 TABLE 38 OCULAR TOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 114 TABLE 39 OCULAR TOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 115 8.7 ORGAN TOXICITY 115 8.7.1 HIGH-CONTENT SCREENING AND CELL-BASED ASSAYS ARE USED TO DETECT ORGAN-SPECIFIC TOXICITY 115 TABLE 40 ORGAN TOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 116 TABLE 41 ORGAN TOXICITY: TE IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 117 8.8 PHOTOTOXICITY 117 8.8.1 VALIDATED NON-ANIMAL METHODS ARE USED TO EVALUATE PHOTO SAFETY OF COSMETICS, PHARMACEUTICALS, & CHEMICALS 117 TABLE 42 PHOTOTOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 118 TABLE 43 PHOTOTOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 119 8.9 DERMAL TOXICITY 119 8.9.1 IN VITRO METHODS FOR DERMAL TOXICITY TESTING ARE EXPECTED TO GAIN RECOGNITION IN COMING YEARS 119 TABLE 44 DERMAL TOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 120 TABLE 45 DERMAL TOXICITY: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 121 8.10 OTHER ENDPOINTS & TESTS 121 TABLE 46 OTHER ENDPOINTS & TESTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 122 TABLE 47 OTHER ENDPOINTS & TESTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 122 9 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY 123 9.1 INTRODUCTION 124 FIGURE 24 TOXICOGENOMICS SEGMENT TO EXHIBIT HIGHEST CAGR IN IN VITRO TOXICOLOGY TESTING MARKET DURING FORECAST PERIOD 124 TABLE 48 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 124 TABLE 49 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 125 9.2 CELL CULTURE 125 9.2.1 CELL- & TISSUE-BASED TECHNOLOGIES ARE WIDELY ADOPTED IN IN VITRO TESTING 125 TABLE 50 CELL CULTURE: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 126 TABLE 51 CELL CULTURE: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 126 9.3 HIGH-THROUGHPUT 127 9.3.1 INCREASING USE OF HIGH-CONTENT IMAGING TECHNOLOGIES IN TOXICITY TESTING BOOSTS MARKET GROWTH 127 TABLE 52 HIGH-THROUGHPUT: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 128 TABLE 53 HIGH-THROUGHPUT: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 128 9.4 TOXICOGENOMICS 129 9.4.1 IMPROVEMENTS IN PROTEOMIC TECHNOLOGIES ENHANCE STUDY OF GENES & PROTEIN ACTIVITIES DURING TOXICITY ANALYSIS 129 TABLE 54 TOXICOGENOMICS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 129 TABLE 55 TOXICOGENOMICS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 130 10 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY 131 10.1 INTRODUCTION 132 FIGURE 25 PHARMACEUTICALS & BIOPHARMACEUTICALS INDUSTRY TO HOLD LARGEST MARKET SHARE THROUGHOUT FORECAST PERIOD 132 TABLE 56 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 132 TABLE 57 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 133 10.2 COVID-19 IMPACT, BY INDUSTRY 133 10.3 PHARMACEUTICALS & BIOPHARMACEUTICALS 133 10.3.1 DRUG ATTRITION RATE LEADS TO HIGH ADOPTION OF IN VITRO TESTING ASSAYS IN EARLY STAGES OF DRUG DEVELOPMENT 133 TABLE 58 PHARMACEUTICALS & BIOPHARMACEUTICALS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 135 TABLE 59 PHARMACEUTICALS & BIOPHARMACEUTICALS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 136 10.4 COSMETICS & HOUSEHOLD PRODUCTS 136 10.4.1 BAN ON ANIMAL TESTING LEADING TO ADOPTION OF IN VITRO ASSAYS FOR SAFETY TESTING 136 TABLE 60 COSMETICS & HOUSEHOLD PRODUCTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 137 TABLE 61 COSMETICS & HOUSEHOLD PRODUCTS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 138 10.5 FOOD 138 10.5.1 INCREASING FOCUS ON FOOD SAFETY DRIVES REQUIREMENT FOR IN VITRO TOXICOLOGY TESTING PRODUCTS 138 TABLE 62 TYPES OF TOXICOLOGY TESTS IN FOOD 139 TABLE 63 FOOD: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 140 TABLE 64 FOOD: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 141 10.6 CHEMICALS 141 10.6.1 INCREASING FOCUS ON ORGANOID-BASED IN VITRO APPROACHES FOR CHEMICALS TESTING PROPELS MARKET GROWTH 141 TABLE 65 CHEMICALS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 142 TABLE 66 CHEMICALS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 143 11 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD 144 11.1 INTRODUCTION 145 FIGURE 26 IN-SILICO MODELS TO RECORD HIGHEST CAGR IN IN VITRO TOXICOLOGY TESTING MARKET DURING FORECAST PERIOD 145 TABLE 67 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 145 TABLE 68 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 146 11.2 CELLULAR ASSAYS 146 11.2.1 DEVELOPMENT OF MULTI-PARAMETER ASSAYS WILL PROVIDE SIGNIFICANT GROWTH OPPORTUNITIES TO MARKET PLAYERS 146 TABLE 69 CELLULAR ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 147 TABLE 70 CELLULAR ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 148 11.3 BIOCHEMICAL ASSAYS 148 11.3.1 BIOCHEMICAL ASSAYS ARE ADOPTED AT HIGHER RATE IN PHARMACEUTICALS INDUSTRY THAN CHEMICALS AND FOOD INDUSTRIES 148 TABLE 71 BIOCHEMICAL ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 149 TABLE 72 BIOCHEMICAL ASSAYS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 150 11.4 IN-SILICO MODELS 150 11.4.1 IN-SILICO MODELS ARE EXPECTED TO WITNESS HIGHEST CAGR FROM 2022 TO 2027 150 TABLE 73 IN-SILICO MODELS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 151 TABLE 74 IN-SILICO MODELS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 152 11.5 EX-VIVO MODELS 152 11.5.1 EX-VIVO MODELS ARE WIDELY USED IN SKIN AND EYE TOXICOLOGY TESTING IN COSMETICS INDUSTRY 152 TABLE 75 EX-VIVO MODELS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2019–2021 (USD MILLION) 153 TABLE 76 EX-VIVO MODELS: IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHY, 2022–2027 (USD MILLION) 154 12 IN VITRO TOXICOLOGY TESTING MARKET, BY GEOGRAPHIC ANALYSIS 155 12.1 INTRODUCTION 156 12.2 COVID-19 IMPACT, BY REGION 156 FIGURE 27 IN VITRO TOXICOLOGY TESTING MARKET: GEOGRAPHIC SNAPSHOT 157 TABLE 77 IN VITRO TOXICOLOGY TESTING MARKET, BY REGION, 2019–2021 (USD MILLION) 157 TABLE 78 IN VITRO TOXICOLOGY TESTING MARKET, BY REGION, 2022–2027 (USD MILLION) 158 12.3 EUROPE 158 FIGURE 28 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET SNAPSHOT 159 TABLE 79 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY, 2019–2021 (USD MILLION) 160 TABLE 80 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY, 2022–2027 (USD MILLION) 160 TABLE 81 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 161 TABLE 82 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 161 TABLE 83 EUROPE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 162 TABLE 84 EUROPE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 162 TABLE 85 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 163 TABLE 86 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 163 TABLE 87 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 164 TABLE 88 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 164 TABLE 89 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 164 TABLE 90 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 165 TABLE 91 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 165 TABLE 92 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 165 12.3.1 GERMANY 166 12.3.1.1 Germany holds the largest share of the European market 166 TABLE 93 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 167 TABLE 94 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 167 TABLE 95 GERMANY: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 168 TABLE 96 GERMANY: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 168 TABLE 97 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 169 TABLE 98 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 169 TABLE 99 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 170 TABLE 100 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 170 TABLE 101 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 170 TABLE 102 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 171 TABLE 103 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 171 TABLE 104 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 171 12.3.2 UK 172 12.3.2.1 Rising awareness, growing R&D, and increasing collaborations for In Vitro Toxicology Testing Market are key indicators of market growth in UK 172 TABLE 105 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 173 TABLE 106 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 173 TABLE 107 UK: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 174 TABLE 108 UK: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022-2027 (USD MILLION) 174 TABLE 109 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 175 TABLE 110 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 175 TABLE 111 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 176 TABLE 112 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 176 TABLE 113 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 176 TABLE 114 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 177 TABLE 115 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 177 TABLE 116 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 177 12.3.3 FRANCE 178 12.3.3.1 Proteomics research initiatives supported by government aid market growth in France 178 TABLE 117 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 179 TABLE 118 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 179 TABLE 119 FRANCE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 180 TABLE 120 FRANCE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 180 TABLE 121 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 181 TABLE 122 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 181 TABLE 123 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 182 TABLE 124 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 182 TABLE 125 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 182 TABLE 126 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 183 TABLE 127 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 183 TABLE 128 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 183 12.3.4 ITALY 184 12.3.4.1 Italian market growth is mainly driven by increased volume of life sciences research 184 TABLE 129 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 184 TABLE 130 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 185 TABLE 131 ITALY: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 185 TABLE 132 ITALY: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 186 TABLE 133 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 186 TABLE 134 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 187 TABLE 135 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 187 TABLE 136 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 188 TABLE 137 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 188 TABLE 138 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 188 TABLE 139 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 189 TABLE 140 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 189 12.3.5 SPAIN 189 12.3.5.1 Spain’s growing Chemicals industry stimulates in vitro toxicology testing market growth 189 TABLE 141 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 190 TABLE 142 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 190 TABLE 143 SPAIN: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 191 TABLE 144 SPAIN: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 191 TABLE 145 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 192 TABLE 146 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 192 TABLE 147 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 193 TABLE 148 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 193 TABLE 149 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 193 TABLE 150 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 194 TABLE 151 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 194 TABLE 152 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 194 12.3.6 REST OF EUROPE 195 TABLE 153 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 196 TABLE 154 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 196 TABLE 155 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 196 TABLE 156 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 197 TABLE 157 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 197 TABLE 158 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 198 TABLE 159 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 198 TABLE 160 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 199 TABLE 161 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 199 TABLE 162 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 199 TABLE 163 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 200 TABLE 164 REST OF EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 200 12.4 NORTH AMERICA 201 FIGURE 29 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET SNAPSHOT 202 TABLE 165 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY, 2019–2021 (USD MILLION) 202 TABLE 166 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY, 2022–2027 (USD MILLION) 203 TABLE 167 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 203 TABLE 168 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 203 TABLE 169 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 204 TABLE 170 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 204 TABLE 171 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 205 TABLE 172 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 205 TABLE 173 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 206 TABLE 174 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 206 TABLE 175 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 206 TABLE 176 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 207 TABLE 177 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 207 TABLE 178 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 207 12.4.1 US 208 12.4.1.1 US dominates North American market due to growing focus on biomarker discovery and research in structure-based drug design 208 TABLE 179 US: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 209 TABLE 180 US: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 209 TABLE 181 US: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 210 TABLE 182 US: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 210 TABLE 183 US: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 211 TABLE 184 US: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 211 TABLE 185 US: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 212 TABLE 186 US: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 212 TABLE 187 US: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 212 TABLE 188 US: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 213 TABLE 189 US: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 213 TABLE 190 US: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 213 12.4.2 CANADA 214 12.4.2.1 Strong support to carry out R&D in pharmaceutical and proteomics fields fosters market growth in Canada 214 TABLE 191 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2019–2021 (USD MILLION) 215 TABLE 192 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT & SERVICE, 2022–2027 (USD MILLION) 215 TABLE 193 CANADA: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2019–2021 (USD MILLION) 216 TABLE 194 CANADA: IN VITRO TOXICOLOGY TESTING ASSAYS MARKET, BY TYPE, 2022–2027 (USD MILLION) 216 TABLE 195 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2019–2021 (USD MILLION) 217 TABLE 196 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICOLOGY ENDPOINT & TEST, 2022–2027 (USD MILLION) 217 TABLE 197 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2019–2021 (USD MILLION) 218 TABLE 198 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2022–2027 (USD MILLION) 218 TABLE 199 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2019–2021 (USD MILLION) 218 TABLE 200 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY, 2022–2027 (USD MILLION) 219 TABLE 201 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2019–2021 (USD MILLION) 219 TABLE 202 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2022–2027 (USD MILLION) 219
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