Summary

Overview
The global chromoendoscopy agents market reached US$ XX million in 2023 and is expected to reach US$ XX million by 2031, growing at a CAGR of XX% during the forecast period 2024-2031.
Chromoendoscopy is the term for advanced endoscopic imaging technologies that offer contrast enhancement of the mucosal surface, blood vessels, and the gastrointestinal tract. Chromoendoscopy improves the detection of gastrointestional lesions in cases of colorectal cancer, inflammatory bowel disease, polyps etc. Several agents are used to produce the color contrast during the endoscopic proceudre which can be typically classified into absorbable stains, contrast stains and reactive stains.
Absorbable stains for instance, methylene blue and lugol’s solutions get absorbed by specific epithelial cell membranes, contrast stains permeate through mucosal cervices and highlight the topography of cell surface. Reactive stains undergo chemical interaction with specific cellular contents and show the deviations or irregulaties by change in the color.
Market Dynamics: Drivers
Rising prevalance of gastrointestinal conditions
Endoscopic devices have been widely used for diagnostic purposes in various gastrointestinal conditions such as inflammatory bowel disease, colorectal cancer, gastrointestinal ulcers, GERD, dyspepsic leisons, esophageal varicies etc. Among these several chronic conditions such as IBD, colorectal cancer require constant follow-up to study the prognosis. Endoscopy has been one of the gold-standard diagnostic tool for these conditions and has been widely adopted all across the world.
With the advent of technology, the traditional endoscopy procedures has been integarated with various platforms to ease out the diagostic difficulties. One of such integration is chromoendoscopy in which a dye has a vital role in producing a clear contrast endoscopic images of the internal body. With the rising prevalance of these chronic conditions, the adoption of the chromoendoscopy technique is expected to rise in the forecast period.
For instance, according to an epidemological study published in Springer Nature, by 2035, in comparision with the year 2020, the prevalance of inflammatory bowel disease is expected to increase 2.3 times in North Africa, 2.5 times in Iran, 4 times in India, 1.5 times in East Asian region, and 1.6 times in south east asia & high income Asian countries.
Also, according to an epidemiological study published in National Center for Biotechnology Information the prevalance of esophageal cancer is expected to increase by 31.4% by 2030 and 63.5% by 2040 as compared to 2020. Moreover, the mortality is expected to rise by 33.0% by 2030 and 68% by 2040.
Moreover, in April 2024, a meta-analysis study published in The American Journal of Gastroenterology stated that the dye based chromoendoscopy has been found to be superior to any other high defenition scopes in IBD patients for dysplasia detection. The research further suggested the usage of dye based chromoendoscopy for surveillance of high-risk IBD patients.
Chromoendoscopy plays a crucial role in the early diagnosis of gastrointestinal conditions more better than the regular endoscopy. With the rising emphasis on chromoendoscopy it is expected that this technology will play a vital role in diagnosing these higly prevalant gastrointestinal conditions in the upcoming years.
Moreover, the rising applications of chromoendoscopy, rising emphasis on minimally invasive diagnostic procedures, and technological advancements in chrmoendoscopy technique are expected to drive the market growth
Restraints
Factors such as lack of skilled professionals, availability of alternative technolgies are expected to restrain the market growth.
Segment Analysis
The global chromoendoscopy agents market is segmented based on type, indication, end user and region.
The contrast stains in the type segment accounted for approximately 42.2% of the global chromoendoscopy agents market share
The contrast stains are one of the widely used dyes in the chromoendoscopic procedures. They enhance the visualization of irregulaties on the gastrointestinal tract and easily detect polyops, cancerous cells, and inflammation. As compared with the other types of dye’s, contrast dye’s are easy to apply which require a simple topical application using a spraying device. Contrast stains provide selective staining when applied to the mucosal surface, they specifically highlight the target areas which allow the technician to easily differentiate between the normal and abnormal tissues. Among contrast stains, indigo carmine is the widely used stain due to its indispensible applications.
For instance, on june 22, 2023, an article published by the Korean Society of Gastrointestinal Endoscopy stated that Indigo carmine is the most widely used dye in the dye based chromoendoscopy procedure due to its minimal to no side effects, ease of use and administration, no absorption by the tissue.
Geographical Analysis
North America is expected to dominate the market with 41.2% share in the Global chromoendoscopy agents Market
North America is expected to dominate the market due to highest prevalance of chronic gastrointestinal condition such as inflammatory bowel disease, colorectal cancer, barretts esophagus etc. The region has high number of well-equipped hospitals and diagnostic centers with ease of access to all the citizens. Moreover, U.S. has high per capita spending on healthcare, as compared to other high income countries, which is a major contributing factor for greater market share for the region.
For instance, on October 04, 2023, according to the data published by The Commonwealth Fund, the patients of U.S. receive extensive healthcare services upon phyisican visits, and have access to advanced technology diagnostic services as compared to any other OECD nation.
Competitive Landscape
The major players in the chromoendoscopy agents market include Macsen Labs, Cosmo Pharmaceuticals, Merck KGaA, Diagmed Healthcare, Provepharm Life Solutions, LobaChemie Pvt. Ltd, Thermo Fisher Scientific Inc., STERIS., Micro-Tech Endoscopy and Vytil among others.
COVID-19 Impact Analysis
The global market for chromoendoscopy agents was affected by the COVID-19 pandemic. During the pandemic, many non-emergency endoscopic procedures were cancelled to prioritize the healthcare resources for the care of covid patients. As compared to pre-pandemic period, there has been a reduction in procedure volumes, with great emphasis shifted toward covid patient care.
For instance, on November 11, 2022, a systematic review published in the National Center for Biotechnology information has stated that during pandemic peak period, several countries across the globe have reported a reduction in the regular endoscopic procedures. The reduction rate has ranged from 40% to 85% as compared to pre-pandemic period.
Market Segmentation
By Type
• Absorptive Agents
o Lugol’s Iodine
o Methylene Blue
o Crystal Violet
o Others
• Contrast Stains
o Indigo Carmine
o Others
• Reactive Stains
o Congo Red
o Phenol Red
o Others
By Indication
• Barrett’s Esophagus
• Gastric Intestinal Metaplasia
• Colorectal Dysplasia.
• Inflammatory Bowel Disease
• Others
By End Users
• Hospitals & Clinics
• Diagnostic Centers
• Ambulatory Surgical Centers
• Others
By Region
• North America
o U.S.
o Canada
o Mexico
• Europe
o Germany
o U.K.
o France
o Spain
o Italy
o Rest of Europe
• South America
o Brazil
o Argentina
o Rest of South America
• Asia-Pacific
o China
o India
o Japan
o South Korea
o Rest of Asia-Pacific
• Middle East and Africa
Why Purchase the Report?
• To visualize the global chromoendoscopy agents market segmentation based on type, indication, end user and region as well as understand key commercial assets and players.
• Identify commercial opportunities by analyzing trends and co-development.
• Excel data sheet with numerous data points of chromoendoscopy agents market-level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as excel consisting of key products of all the major players.
The global chromoendoscopy agents market report would provide approximately 62 tables, 55 figures, and 187 Pages.
Target Audience 2024
• Manufacturers/ Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies

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Table of Contents

1. Methodology and Scope
1.1. Research Methodology
1.2. Research Objective and Scope of the Report
2. Definition and Overview
3. Executive Summary
3.1. Snippet by Type
3.2. Snippet by Indication
3.3. Snippet by End User
4. Dynamics
4.1. Impacting Factors
4.1.1. Drivers
4.1.1.1. Rising prevalence of gastrointestinal conditions
4.1.1.2. Rising applications of chromoendoscopy
4.1.2. Restraints
4.1.2.1. Lack of skilled professionals
4.1.3. Opportunity
4.1.4. Impact Analysis
5. Industry Analysis
5.1. Porter's Five Force Analysis
5.2. Supply Chain Analysis
5.3. Pricing Analysis
5.4. Regulatory Analysis
5.5. Unmet Needs
5.6. PESTEL Analysis
5.7. Patent Analysis
5.8. SWOT Analysis
6. COVID-19 Analysis
6.1. Analysis of COVID-19
6.1.1. Scenario Before COVID
6.1.2. Scenario During COVID
6.1.3. Scenario Post COVID
6.2. Pricing Dynamics Amid COVID-19
6.3. Demand-Supply Spectrum
6.4. Government Initiatives Related to the Market During Pandemic
6.5. Manufacturers Strategic Initiatives
6.6. Conclusion
7. By Type
7.1. Introduction
7.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Type
7.1.2. Market Attractiveness Index, By Type
7.2. Absorptive Agents*
7.2.1. Introduction
7.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
7.2.2.1. Lugol’s Iodine
7.2.2.2. Methylene Blue
7.2.2.3. Crystal Violet
7.2.2.4. Others
7.3. Contrast Strains
7.3.1. Indigo Carmine
7.3.2. Others
7.4. Reactive Stains
7.4.1. Congo Red
7.4.2. Phenol Red
7.4.3. Others
8. By Indication
8.1. Introduction
8.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Indication
8.1.2. Market Attractiveness Index, By Indication
8.2. Barrett’s Esophagus*
8.2.1. Introduction
8.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
8.2.3. Gastric Intestinal Metaplasia
8.3. Colorectal Dysplasia
8.4. Inflammatory Bowel Disease
8.5. Others
9. By End Users
9.1. Introduction
9.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By End Users
9.1.2. Market Attractiveness Index, By End Users
9.1.3. Hospitals & Clinics*
9.1.4. Introduction
9.1.5. Market Size Analysis and Y-o-Y Growth Analysis (%)
9.1.6. Diagnostic Centers
9.1.7. Ambulatory Surgical Centers
9.2. Others
10. Competitive Landscape
10.1. Competitive Scenario
10.2. Market Positioning/Share Analysis
10.3. Mergers and Acquisitions Analysis
11. Company Profiles
11.1. Macsen Labs
11.1.1. Company Overview
11.1.2. Product Portfolio and Description
11.1.3. Financial Overview
11.1.4. Key Developments
11.2. Cosmo Pharmaceuticals
11.3. Merck KGaA
11.4. Diagmed Healthcare
11.5. Provepharm Life Solutions
11.6. LobaChemie Pvt. Ltd
11.7. Thermo Fisher Scientific Inc.
11.8. STERIS.
11.9. Micro-Tech Endoscopy
11.10. Vytil
LIST NOT EXHAUSTIVE
12. Appendix
12.1. About Us and Services
12.2. Contact Us