Summary

Market Overview
The North America liquid biopsy market was valued at US$ 1464.00 million in 2023 and is estimated to reach US$ 5110.34 million by 2031, growing at a CAGR of 17.1% during the forecast period from 2024-2031. 
Liquid biopsies are commonly used in oncology to detect and monitor cancer. The presence of circulating tumor DNA or other cancer-related biomarkers in the blood can provide information about the genetic characteristics of tumors, helping with diagnosis, treatment selection, and monitoring treatment response. Liquid biopsies have the potential to detect cancer at an earlier stage than traditional methods, as they can identify genetic alterations associated with tumors in their early development. Liquid biopsies enable real-time monitoring of genetic changes in tumors during the course of treatment. This information helps physicians make informed decisions about adjusting treatment strategies.
Market Dynamics
Increasing investments and funding in liquid biopsy
The rise of investments can play a crucial role in driving the liquid biopsy market growth. Adequate funding can support the commercialization efforts of liquid biopsy companies. 
This includes obtaining regulatory approvals, establishing manufacturing processes, and creating marketing strategies. Investments provide the necessary resources for these companies to bring their products to market efficiently. Thus, rise in investments and funding helps to boost the market growth. For instance, in October 2023, Aqtual liquid biopsy startup raised $16 million in Series A financing to further advance its cell-free DNA (cfDNA) analysis platform to develop blood-based assays to help select effective treatments for chronic diseases and cancer, starting with rheumatoid arthritis.
Additionally, in July 2022, Delfi Diagnostics, Inc., a pioneering developer of a new class of high-performance, accessible liquid biopsy tests for early cancer detection and monitoring, raised a Series B funding of $225 million. This funding will support the continued development and commercialization of high-quality and accessible blood tests for single-cancer early detection, multi-cancer early detection, and treatment monitoring.
Moreover in December 2023, researchers from the University of California, Los Angeles (UCLA) Health Jonsson Comprehensive Cancer Center received two grants totaling $9.1 million from the National Cancer Institute to advance liquid biopsy technologies for the early detection of cancer, which can significantly improve treatment outcomes and reduce the number of deaths caused by the disease. Thus, above factors help to boost the market growth.
Market Opportunity
Rising opportunities in brain space
Liquid biopsy presents several opportunities in the diagnosis of brain tumors, offering a less invasive and potentially more accessible method for detecting and monitoring these complex and often challenging-to-diagnose conditions. For instance, the British Journal of Centre in 2023, stated that, in recent years, liquid biopsy has emerged as an alternative method to diagnose and monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the repetitive collection of diverse cellular and acellular analytes from various biofluids in a non/minimally invasive manner. 
This strategy is of greater significance for high-grade brain malignancies such as glioblastoma as the quantity and accessibility of tumors are limited, and there are collateral risks of compromised life quality coupled with surgical interventions. 
Currently, blood and cerebrospinal fluid (CSF) are the most common biofluids used to collect circulating cells and biomolecules of tumor origin. These liquid biopsy analytes have created opportunities for real-time investigations of distinct genetic, epigenetic, transcriptomics, proteomics, and metabolomics alterations associated with brain tumors.
Market Segmentation
By Circulating Biomarker
Circulating Tumor Cells
Circulating Tumor DNA (ctDNA)/Cell-free DNA (cfDNA)
Extracellular Vesicles
By Product & Services
Kits & Reagents
Instruments
Services
By Application
Cancer Applications
Non-Cancer Applications
By Technology
Multi-Gene-Parallel Analysis (NGS)
Single Gene Analysis (PCR Microarrays)
By End User
Hospitals and Physician Laboratories
Research Centers
Others
By Country
US
Canada
Mexico
Key players
Merck & Co, Inc
F. Hoffmann-La Roche AG
Exosome Diagnostics, Inc.
Illumina Inc.
Guardant Health Inc
Thermo Fisher Scientific Inc.
NeoGenomics Inc
Qiagen NV
BioChain Institute Inc.
Biocept Inc.
Why Purchase the Report?
To visualize the North America Liquid Biopsy Market segmentation based on the circulating biomarker, product & services, application, technology, end-user, and region and understand key commercial assets and players.
Identify commercial opportunities by analyzing trends and co-development. 
Excel data sheet with numerous liquid biopsy market-level data points with all segments.
PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
Product mapping available as Excel consisting of key products of all the major players.
The North America Liquid Biopsy Market Report Would Provide Approximately 77 Tables, 77 Figures, and 195 Pages.
Target Audience 2024
Manufacturers/ Buyers
Industry Investors/Investment Bankers
Research Professionals
Emerging Companies

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Table of Contents

Methodology and Scope
Research Methodology
Research Objective and Scope of the Report
Definition and Overview
Executive Summary
Snippet by Circulating Biomarker
Snippet by Product & Services
Snippet by Application
Snippet by Technology
Snippet by End User
Snippet by Region
Dynamics
Impacting Factors
Drivers
Recent Advances in Liquid Biopsy Technologies for Cancer Biomarker Detection
Emerging Liquid Biopsy Techniques for Blood-based Detection of Tumor DNA
Restraints
Challenges in the Development of Liquid Biopsy Kits 
Opportunity
Increasing Research Collaborations
Impact Analysis
Industry Analysis 
Porter’s 5 Forces Analysis
Supply Chain Analysis
Unmet Needs
Regulatory Analysis
COVID-19 Analysis
Analysis of COVID-19
Scenario Before COVID-19
Scenario During COVID-19
Scenario Post COVID-19
Pricing Dynamics Amid COVID-19
Demand-Supply Spectrum
Government Initiatives Related to the Market During the Pandemic
Manufacturers’ Strategic Initiatives
Conclusion
Russia-Ukraine War Analysis
By Circulating Biomarker
Introduction
Market Size Analysis and Y-o-Y Growth Analysis (%), By Circulating Biomarker
Market Attractiveness Index, By Circulating Biomarker
Circulating Tumor Cells*
Introduction
Market Size Analysis and Y-o-Y Growth Analysis (%)
Circulating Tumor DNA (ctDNA)
Cell-free DNA (cfDNA)
Extracellular Vesicles
By Product & Services
Introduction
Market Size Analysis and Y-o-Y Growth Analysis (%), By Product & Services
Market Attractiveness Index, By Product & Services
Kits & Reagents*
Introduction
Market Size Analysis and Y-o-Y Growth Analysis (%)
Instruments
Services
By Application
Introduction
Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
Market Attractiveness Index, By Application
Cancer Applications*
Introduction
Market Size Analysis and Y-o-Y Growth Analysis (%)
Breast Cancer
Colorectal Cancer
Lung Cancer
Prostate Cancer
Liver Cancer
Other
Non-Cancer Applications
Non-Invasive Prenatal Testing (NIPT)
Organ Transplantations
Infectious Disease Testing
By Technology
Introduction
Market Size Analysis and Y-o-Y Growth Analysis (%), By Technology
Market Attractiveness Index, By Technology
Multi-gene-parallel Analysis (NGS)*
Introduction
Market Size Analysis and Y-o-Y Growth Analysis (%)
Single Gene Analysis (PCR Microarrays)
By End User
Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
Market Attractiveness Index, By End User
Hospitals and Physician Laboratories*
Introduction
Market Size Analysis and Y-o-Y Growth Analysis (%)
Research Centers
Others
By Country
Introduction
Market Size Analysis and Y-o-Y Growth Analysis (%), By Region
Market Attractiveness Index, By Region
North America
Introduction
Key Region-Specific Dynamics
Market Size Analysis, and Y-o-Y Growth Analysis (%), By Circulating Biomarker
Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product & Services
Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
Market Size Analysis, and Y-o-Y Growth Analysis (%), By Technology
Market Size Analysis, and Y-o-Y Growth Analysis (%), By End User
Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
The U.S.
Canada
Mexico
Competitive Landscape
Competitive Scenario
Product Benchmarking
Company Share Analysis
Key Developments and Strategies
Company Profiles
Bio-Rad Laboratories*
Company Overview
Product Portfolio and Description
Financial Overview
Key Developments
F. Hoffmann-La Roche AG
Exosome Sciences Inc.
Grail Inc
Guardant Health
Thermo Fisher Scientific Inc.
Inivata Ltd
Illumina Inc
LungLife AI Inc
Qiagen NV (*LIST NOT EXHAUSTIVE) 
Appendix
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