Summary

Global EV-Based Liquid Biopsy Market Overview

The global EV-based liquid biopsy market was valued at $78.22 million in 2022 and is anticipated to reach $455.53 million by 2032, witnessing a CAGR of 19.73% during the forecast period 2023-2032. The global EV-based liquid biopsy market is expected to be driven by ongoing technological advancements, increasing adoption by healthcare providers, and a growing focus on personalized medicine.

Market Lifecycle Stage

The global EV-based liquid biopsy market is in progressing phase, which can be attributed to the increase in academic research and approval of products in the market. Furthermore, the expanding applications of EV-based liquid biopsy in personalized medicine and precision oncology are projected to drive further market expansion.

Impact

The adoption of EV-based liquid biopsy has revolutionized disease diagnosis and monitoring, offering numerous benefits over traditional biopsy methods. Its non-invasiveness, real-time monitoring capabilities, and potential for early disease detection have transformed the field of healthcare diagnostics. By providing a less invasive and more accessible method for detecting and monitoring diseases, particularly cancer, EV-based liquid biopsy has improved patient experiences, reduced healthcare costs, and enhanced overall healthcare outcomes. In addition, the entry of several established players, such as Thermo Fisher Scientific Inc., QIAGEN N.V., and Bio-Techne Corporation, is expected to aid the market growth.

Furthermore, the growth of the EV-based liquid biopsy market has stimulated research and development activities, fostered collaborations between industry players and academic institutions, and generated economic opportunities.

Market Segmentation:

Segmentation 1: by Offering
• Kits and Assays
• Services
• Instruments

Kits and Assays Segment to Dominate the Global EV-Based Liquid Biopsy Market (by Offering)

Based on offering, the kits and assays segment dominated the global EV-based liquid biopsy market in FY2022. The increasing adoption of isolation kits, assays, and accessories contributed to the prominence of this segment. Various exosome and EV isolation kits are being used to carry out several procedures and liquid biopsy tests.

Segmentation 2: by Technology
• Isolation
• Analysis

Isolation Segment to Dominate the Global EV-Based Liquid Biopsy Market (by Technology)

Based on technology, the isolation segment dominated the global EV-based liquid biopsy market in FY2022. Under isolation technology, precipitation emerged as the most common technology used.

Segmentation 3: by Workflow
• Sample Preparation
• Sequencing
• Data Analysis

Sample Preparation Segment to Dominate the Global EV-Based Liquid Biopsy Market (by Workflow)

Based on workflow, the EV-based liquid biopsy market was dominated by the sample preparation segment in FY2022. The sample preparation or pre-analytical phase in the EV-based liquid biopsy workflow includes specimen collection, stabilization, transport, enrichment, processing, isolation, and quality assessment of the analyte.

Segmentation 4: by End User
• Academic and Research Institutes
• Clinical Laboratories
• Pharmaceutical and Biotechnology Companies

Academic and Research Institutes Segment to Dominate the Global EV-Based Liquid Biopsy Market (by End User)

Based on end user, academic and research segment accounted for the largest share of the global EV-based liquid biopsy market in FY2022. Academic and research institutes play a vital role in the adoption of EV-based liquid biopsy methods, serving as essential facilities for both companies and independent academic research. These institutions are primarily engaged in research activities aimed at identifying biomarkers, developing drugs, and conducting cell analysis to acquire targets.

Segmentation 5: by Region
• North America
• Europe
• Asia-Pacific
• Latin America and Middle East
• Rest-of-the-World

In 2022, the North America region dominated the global EV-based liquid biopsy market, and it is expected to hold its dominance throughout the forecast period 2023-2032. However, the Asia-Pacific (APAC) region, constituting several emerging economies, is expected to register the highest CAGR of 21.64% in the market during the forecast period 2023-2032.

Demand – Drivers, Restraints, and Opportunities

Market Demand Drivers:

• Abundance and Remarkable Stability of Exosomes Compared to CfDNA or CTCs
• Amplified Funding and Dedicated Research Efforts
• Increasing Prevalence of Cancers

Market Restraints:

• Lack of Standardized EV Isolation and Characterization Protocols
• Lack of Precise EV Subtype Classification and Biomarkers Validation

Market Opportunities:

• Advancements in EV-Based Liquid Biopsy Technologies
• Development of New EV-Based Biomarkers
• Approved Products in the Market

How can this report add value to an organization?

Workflow/Innovation Strategy: The EV-based liquid biopsy market (by offering) has been segmented into kits and assays, instruments, and services. Moreover, the study provides the reader with a detailed understanding of the different types of technologies, end-users, and sample types used in these tests.

Growth/Marketing Strategy: EV-based liquid biopsy has tremendous growth potential due to its ability to revolutionize non-invasive cancer detection and monitoring. By analyzing the cargo of EVs, researchers can gain insights into the presence, type, and characteristics of tumors without directly accessing the tumor site.

Competitive Strategy: Key players in the EV-based liquid biopsy market have been analyzed and profiled in the study, including manufacturers. Moreover, a detailed competitive benchmarking of the players operating in the EV-based liquid biopsy market has been done to help the reader understand how players stack against each other, presenting a clear market landscape.

Key Market Players and Competition Synopsis

EV-based liquid biopsy refers to the use of extracellular vesicles (EVs) as a non-invasive diagnostic tool for detecting and monitoring various diseases, including cancer. The global EV-based liquid biopsy market has experienced substantial growth driven by technological advancements, rising demand for non-invasive diagnostics, and the global increase in cancer prevalence.

Key Companies Profiled:

• Abcam plc
• Bio-Techne Corporation
• Horiba Ltd.
• Qiagen N.V.
• Thermo Fisher Scientific, Inc.
• Malvern Panalytical Ltd
• Lonza Group AG
• Revvity, Inc. (PerkinElmer, Inc.)
• Takara Bio Inc.
• Norgen Biotek Corp.

ページTOPに戻る

Table of Contents

1 Definition
1.1 Inclusion and Exclusion Criteria
2 Research Scope
2.1 Target Audience
2.2 Key Questions Answered in the Report:
3 Research Methodology
3.1 Global EV-Based Liquid Biopsy Market: Research Methodology
3.2 Primary Data Sources
3.3 Secondary Data Sources
3.4 Market Estimation Model
3.5 Criteria for Company Profiling
4 Markets Overview
4.1 Market Introduction
4.2 Current and Future State of EV-Based Liquid Biopsy in Industries
4.3 Current Market Size and Growth Potential, $Million, 2022-2032
4.4 COVID-19 Impact on Global EV-based Liquid Biopsy Market
4.4.1 Impact on Operations
4.4.2 COVID-19 Impact: Current Scenario of the Market
5 Methods of EV Isolation and Analysis
5.1 Overview
5.1.1 Evs Introduction
5.2 Isolation Methods
5.2.1 EV Isolation Techniques Utilizing Ultracentrifugation Methods
5.2.1.1 Differential Ultracentrifugation
5.2.1.2 Density Gradient Centrifugation
5.2.1.3 Moving Zone or Rate-Zonal Centrifugation
5.2.1.4 Isopycnic Centrifugation
5.2.2 EV Isolation Techniques Utilizing Size-Based Methods
5.2.2.1 Ultrafiltration
5.2.2.2 Sequential Filtration
5.2.2.3 Size Exclusion Chromatography (SEC)
5.2.2.4 Flow Field-Flow Fractionation (FFFF)
5.2.2.5 Hydrostatic Filtration Dialysis (HFD)
5.2.3 EV Isolation Techniques Utilizing Immunoaffinity Methods
5.2.3.1 Enzyme-Linked Immunosorbent Assay (ELISA)
5.2.3.2 Magneto-Immunoprecipitation
5.2.4 EV Isolation Techniques Utilizing Precipitation Methods
5.2.4.1 Polyethylene Glycol (PEG) Precipitation
5.2.4.2 Lectin Induced Agglutination
5.2.5 EV Isolation Techniques Utilizing Microfluidic Technology
5.2.6 EV Isolation Techniques Utilizing Commercial Kits
5.2.7 Advantages and Disadvantages of the EV Isolation Methods
5.2.8 Novel Approaches for Exosome Isolation
5.3 Analysis Methods
5.3.1 Advantages and Disadvantages of Analysis Methods for Evs
6 Industry Insights
6.1 Overview
6.2 Legal Requirements in the U.S.
6.3 Legal Requirements and Frameworks in Europe
6.4 Legal Requirements and Frameworks in Asia-Pacific
6.5 Reimbursement Scenario
7 Market Dynamics
7.1 Overview
7.2 Impact Analysis
7.3 Market Drivers
7.3.1 Abundance and Remarkable Stability of Exosomes Compared to CfDNA or CTCs
7.3.2 Amplified Funding and Dedicated Research Efforts
7.3.3 Rising Prevalence of Cancers
7.4 Market Restraints
7.4.1 Lack of Standardized EV Isolation and Characterization Protocols
7.4.2 Lack of Precise EV Subtype Classification and Biomarkers Validation
7.5 Market Opportunities
7.5.1 Advancements in EV-Based Liquid Biopsy Technologies
7.5.2 Development of New EV-Based Biomarkers
7.5.3 Approved Products in the Market
8 Competitive Landscape
8.1 Competitive Landscape Overview
8.1.1 Key Developments
8.1.2 Product Launches and Expansion Activities
8.1.3 Merger and Acquisition Activities
8.1.4 Synergistic Activities
8.1.5 License and Agreement Activities
8.1.6 Other Activities
8.2 Market Share Analysis (2022)
8.3 Growth-Share Analysis (2021-2022)
8.3.1 Growth-Share Analysis (by Company)
9 Global EV-Based Liquid Biopsy Market (by Offering),$Million, 2022-2032
9.1 Overview
9.2 Kits and Assays
9.3 Services
9.4 Instruments
10 Global EV-Based Liquid Biopsy Market (by Workflow), $Million, 2022-2032
10.1 Overview
10.1.1 Sample Preparation
10.1.2 Sequencing
10.1.3 Data Analysis
11 Global EV-Based Liquid Biopsy Market (by Technology), $Million, 2022-2032
11.1 Overview
11.2 Isolation Technologies
11.2.1 Precipitation
11.2.2 Ultracentrifugation
11.2.3 Chromatography
11.3 Analysis Technologies
11.3.1 NGS
11.3.2 PCR
11.3.3 Flow Cytometry
12 Global EV-Based Liquid Biopsy Market (by Sample Type), $Million, 2022-2032
12.1 Overview
12.1.1 Blood
12.1.2 Urine
12.1.3 Saliva
12.1.4 Other Biofluids
13 Global EV-Based Liquid Biopsy Market (by End User), $Million, 2022-2032
13.1 Overview
13.2 Academic and Research Institutes
13.3 Pharmaceutical and Biotechnology Companies
13.4 Clinical Laboratories
14 Global EV-Based Liquid Biopsy Market (by Region), $Million, 2022-2032
14.1 Overview
14.2 North America
14.2.1 U.S.
14.2.2 Canada
14.3 Europe
14.3.1 Germany
14.3.2 U.K.
14.3.3 France
14.3.4 Italy
14.3.5 Spain
14.3.6 Rest-of-Europe
14.4 Asia-Pacific
14.4.1 China
14.4.2 Japan
14.4.3 India
14.4.4 South Korea
14.4.5 Australia
14.4.6 Singapore
14.4.7 Rest-of-Asia-Pacific
14.5 Latin America and Middle East
14.5.1 Brazil
14.5.2 Mexico
14.5.3 Saudi Arabia
14.5.4 Rest-of-Latin America and Middle East
14.6 Rest-of-the-World
15 Company Profiles
15.1 Company Overview
15.1.1 Abcam plc
15.1.1.1 Company Overview
15.1.1.2 Role of Abcam plc in the Global EV-Based Liquid Biopsy Market
15.1.1.3 Major Products: Key Specifications
15.1.1.4 Key Competitors
15.1.1.5 Analyst Perspective
15.1.2 Bio-Techne Corporation
15.1.2.1 Company Overview
15.1.2.2 Role of Bio-Techne Corporation in the Global EV-Based Liquid Biopsy Market
15.1.2.3 Major Products: Key Specifications
15.1.2.4 Key Competitors
15.1.2.5 Analyst Perspective
15.1.3 Horiba Ltd.
15.1.3.1 Company Overview
15.1.3.2 Role of Horiba Ltd. in the Global EV-Based Liquid Biopsy Market
15.1.3.3 Major Products: Key Specifications
15.1.3.4 Key Competitors
15.1.3.5 Analyst Perspective
15.1.4 Qiagen N.V.
15.1.4.1 Company Overview
15.1.4.2 Role of Qiagen N.V. in the Global EV-Based Liquid Biopsy Market
15.1.4.3 Major Products: Key Specifications
15.1.4.4 Key Competitors
15.1.4.5 Analyst Perspective
15.1.5 Thermo Fisher Scientific, Inc.
15.1.5.1 Company Overview
15.1.5.2 Role of Thermo Fisher Scientific, Inc. in the Global EV-Based Liquid Biopsy Market
15.1.5.3 Major Products: Key Specifications
15.1.5.4 Key Competitors
15.1.5.5 Analyst Perspective
15.1.6 Malvern Panalytical Ltd
15.1.6.1 Company Overview
15.1.6.2 Role of Malvern Panalytical Ltd in the Global EV-Based Liquid Biopsy Market
15.1.6.3 Major Products: Key Specifications
15.1.6.4 Key Competitors
15.1.6.5 Analyst Perspective
15.1.7 Lonza Group AG
15.1.7.1 Company Overview
15.1.7.2 Role of Lonza Group AG in the Global EV-Based Liquid Biopsy Market
15.1.7.3 Major Products: Key Specifications
15.1.7.4 Key Competitors
15.1.7.5 Analyst Perspective
15.1.8 Revvity, Inc. (PerkinElmer, Inc.)
15.1.8.1 Company Overview
15.1.8.2 Role of Revvity, Inc. (PerkinElmer Inc.) in the Global EV-Based Liquid Biopsy Market
15.1.8.3 Major Products: Key Specifications
15.1.8.4 Key Competitors
15.1.8.5 Analyst Perspective
15.1.9 Takara Bio Inc.
15.1.9.1 Company Overview
15.1.9.2 Role of Takara Bio Inc. in the Global EV-Based Liquid Biopsy Market
15.1.9.3 Major Products: Key Specifications
15.1.9.4 Key Competitors
15.1.9.5 Analyst Perspective
15.1.10 Norgen Biotek Corp.
15.1.10.1 Company Overview
15.1.10.2 Role of Norgen Biotek Corp. in the Global EV-Based Liquid Biopsy Market
15.1.10.3 Major Products: Key Specifications
15.1.10.4 Key Competitors
15.1.10.5 Analyst Perspective
15.1.11 Emerging Companies
15.1.11.1 Mursla Bio
15.1.11.2 Nanostics Inc.
15.1.11.3 Mercy BioAnalytics, Inc.
15.1.11.4 Clara Diagnostics, Inc. (Clara Biotech)
List of Figures
Figure 1: Global EV-Based Liquid Biopsy Market (by Offering), $Million, 2022-2032
Figure 2: Global EV-Based Liquid Biopsy Market (by End User), $Million, 2022 and 2032
Figure 3: Global EV-Based Liquid Biopsy Market (by Region), 2022
Figure 4: Global EV-Based Liquid Biopsy Market Segmentation
Figure 5: Global EV-Based Liquid Biopsy Market Regional Segmentation
Figure 6: Global EV-Based Liquid Biopsy Market Methodology
Figure 7: Primary Research Methodology
Figure 8: Bottom-Up Approach (Segment-Wise Analysis)
Figure 9: Top-Down Approach (Segment-Wise Analysis)
Figure 10: Global EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 11: Subtypes of Evs
Figure 12: Methods of EV-Isolation from Biofluids
Figure 13: Workflow of Differential Ultracentrifugation for Exosome Isolation
Figure 14: Methods of EV-Analysis
Figure 15: Global EV-Based Liquid Biopsy Market – Market Dynamics
Figure 16: Structure of Evs Enveloped by Protective Lipid Membrane
Figure 17: Number of Research Publications on Exosomes, 2015-2021
Figure 18: Share of New Cancer Cases, 2020
Figure 19: Number of Cancer Cases, 2020
Figure 20: Currently Investigated Circulating Biomarkers Associated with Evs
Figure 21: Share of Key Developments and Strategies, January 2019-June 2023
Figure 22: Share of Product Launch and Expansion Activities (by Company), January 2019-June 2023
Figure 23: Share of Synergistic Activities (by Company), January 2019-June 2023
Figure 24: Share of Other Activities (by Company), January 2019-June 2023
Figure 25: Market Share Analysis for Global EV-Based Liquid Biopsy Market, 2022
Figure 26: Growth-Share Analysis for Global EV-Based Liquid Biopsy Market (by Company), 2021-2022
Figure 27: Global EV-Based Liquid Biopsy Market (by Offering), $Million, 2022-2032
Figure 28: Global EV-Based Liquid Biopsy Market (Kits and Assays), $Million, 2022-2032
Figure 29: Global EV-Based Liquid Biopsy Market (Services), $Million, 2022-2032
Figure 30: Global EV-Based Liquid Biopsy Market (Instruments), $Million, 2022-2032
Figure 31: Global EV-Based Liquid Biopsy Market (by Workflow), $Million, 2022 and 2032
Figure 32: Global EV-Based Liquid Biopsy Market (Sample Preparation), $Million, 2022-2032
Figure 33: Global EV-Based Liquid Biopsy Market (Sequencing), $Million, 2022-2032
Figure 34: Global EV-Based Liquid Biopsy Market (Data Analysis), $Million, 2022-2032
Figure 35: Global EV-Based Liquid Biopsy Market (by Technology)
Figure 36: Global EV-Based Liquid Biopsy Market (by Technology), $Million, 2022 and 2032
Figure 37: Global EV-Based Liquid Biopsy Market (Isolation Technologies), $Million, 2022-2032
Figure 38: Global EV-Based Liquid Biopsy Market (Precipitation), $Million, 2022-2032
Figure 39: Global EV-Based Liquid Biopsy Market (Ultracentrifugation), $Million, 2022-2032
Figure 40: Global EV-Based Liquid Biopsy Market (Chromatography), $Million, 2022-2032
Figure 41: Global EV-Based Liquid Biopsy Market (Analysis Technologies), $Million, 2022-2032
Figure 42: Global EV-Based Liquid Biopsy Market (NGS), $Million, 2022-2032
Figure 43: Global EV-Based Liquid Biopsy Market (PCR), $Million, 2022-2032
Figure 44: Global EV-Based Liquid Biopsy Market (Flow Cytometry), $Million, 2022-2032
Figure 45: Global EV-Based Liquid Biopsy Market (by Sample Type)
Figure 46: Global EV-Liquid Biopsy Market (by Sample Type), $Million, 2022 and 2032
Figure 47: Global EV-Based Liquid Biopsy Market (Blood), $Million, 2022-2032
Figure 48: Global EV-Based Liquid Biopsy Market (Urine), $Million, 2022-2032
Figure 49: Global EV-Based Liquid Biopsy Market (Saliva), $Million, 2022-2032
Figure 50: Global EV-Based Liquid Biopsy Market (Other Biofluids), $Million, 2022-2032
Figure 51: Global EV-Based Liquid Biopsy Market (by End User)
Figure 52: Global EV-Based Liquid Biopsy Market (by End User), $Million, 2022 and 2032
Figure 53: Global EV-Based Liquid Biopsy Market (Academic and Research Institutes), $Million, 2022-2032
Figure 54: Global EV-Based Liquid Biopsy Market (Pharmaceutical and Biotechnology Companies), $Million, 2022-2032
Figure 55: Global EV-Based Liquid Biopsy Market (Clinical Laboratories), $Million, 2022-2032
Figure 56: Global EV-Based Liquid Biopsy Market Snapshot (by Region)
Figure 57: Global EV-Based Liquid Biopsy Market (by Region), $Million, 2022-2032
Figure 58: North America EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 59: North America: Market Dynamics
Figure 60: North America EV-Based Liquid Biopsy Market (by Country), $Million, 2022-2032
Figure 61: U.S. EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 62: Canada EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 63: Europe EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 64: Europe: Market Dynamics
Figure 65: Europe EV-Based Liquid Biopsy Market (by Country), $Million, 2022-2032
Figure 66: Germany EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 67: U.K. EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 68: France EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 69: Italy EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 70: Spain EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 71: Rest-of-Europe EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 72: Asia-Pacific EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 73: Asia-Pacific: Market Dynamics
Figure 74: Asia-Pacific EV-Based Liquid Biopsy Market (by Country), $Million, 2022-2032
Figure 75: China EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 76: Japan EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 77: India EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 78: South Korea EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 79: Australia EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 80: Singapore EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 81: Rest-of-Asia-Pacific EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 82: Latin America and Middle East EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 83: Latin America and Middle East: Market Dynamics
Figure 84: Latin America and Middle East EV-Based Liquid Biopsy Market (by Country), $Million, 2022-2032
Figure 85: Brazil EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 86: Mexico EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 87: Saudi Arabia EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 88: Rest-of-Latin America and Middle East EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 89: Rest-of-the-World EV-Based Liquid Biopsy Market, $Million, 2022-2032
Figure 90: Total Number of Companies Profiled
Figure 91: Abcam plc: Product Portfolio
Figure 92: Bio-Techne Corporation: Product Portfolio
Figure 93: Horiba Ltd.: Product Portfolio
Figure 94: Qiagen N.V.: Product Portfolio
Figure 95: Thermo Fisher Scientific, Inc.: Product Portfolio
Figure 96: Malvern Panalytical Ltd: Product Portfolio
Figure 97: Lonza Group AG: Product Portfolio
Figure 98: Revvity, Inc. (PerkinElmer Inc.): Product Portfolio
Figure 99: Takara Bio Inc.: Product Portfolio
Figure 100: Norgen Biotek Corp.: Product Portfolio
List of Tables
Table 1: Current and Future State of EV-Based Liquid Biopsy in Industries
Table 2: Example of Few Commercial Kits Available for EV Isolation
Table 3: Advantages and Disadvantages of the EV Isolation Methods
Table 4: Emerging Methods for the Isolation of Exosomes
Table 5: Advantages and Disadvantages of Analysis Methods for Evs
Table 6: Legal Requirements in the U.S.
Table 7: Legal Landscape for EV-Based Liquid Biopsies in Europe
Table 8: Size and Densities of Evs and Various Lipoproteins
Table 9: Technological Advancements in EV-Based Liquid Biopsy

Press Release