Summary

Report Overview
Global Exosomes Market reached US$ 1.3 billion in 2023 and is expected to reach US$ 2.7 billion by 2031, growing at a CAGR of 15.6% during the forecast period 2024-2031
Exosomes, small vesicles 30 to 200 nm, are secreted from cells to mediate signaling in the tumor necrosis factor (TNF)-induced mesenchymal stem cells (TME). Oncogenic EGFR can be shed from cells and interact with other TME cells. Exosomes from gastric cancer cells can regulate the liver microenvironment and promote liver metastasis. EGFR-containing exosomes can be captured by endothelial cells, eliciting EGFR-dependent responses and VEGF secretion. Exosomes from EGFR-mutated NSCLC can promote CD8+ T cell apoptosis, potentially affecting immunotherapy efficacy.
Market Dynamics: Drivers & Restraints
Rise in the prevalence of cancers.
The increasing prevalence of cancer has led to a growing demand for innovative therapies. Exosome-based technologies, such as liquid biopsy, are being used to analyze biomarkers in bodily fluids like blood, urine, or saliva. Exosomes, as stable carriers of molecular information, are ideal candidates for liquid biopsy approaches. Researchers are exploring the use of exosomal biomarkers for disease progression, treatment response, and detecting minimal residual disease.
For instance, according to the National Center for Health Statistics, In 2023, 1,958,310 new cancer cases and 609,820 cancer deaths are projected to occur in the United States. Cancer incidence increased for prostate cancer by 3% annually from 2014 through 2019 after two decades of decline, translating to an additional 99,000 new cases; otherwise, however, incidence trends were more favorable in men compared to women.
Technical complexity of exosome isolation and technological limitations 
Exosomes, characterized by their size, composition, and cargo, present a technical challenge in isolating them with high purity and specificity. The absence of standardized methods can lead to variability in experimental outcomes and hinder comparability between studies. The isolation process is technically demanding due to the presence of other extracellular vesicles and contaminants. Obtaining pure and high-yield exosome isolation requires sophisticated techniques, which can affect the quality and consistency of the obtained samples. 
Market Segment Analysis
The global exosomes market is segmented based on product type, application, end-user, and region.
The kits and reagents from the product type segment accounted for approximately 47.3% of the exosomes  market share
The kits and reagents from the product type segment accounted for approximately 47.3%. Kits and reagents are essential tools in exosome research and clinical applications. They facilitate the isolation, detection, and analysis of exosomes from biological samples like blood, urine, and cell culture media. These tools ensure high yield and purity while preserving biological integrity. Kits simplify the isolating process, making it accessible to those with limited technical expertise. Reagents, like antibodies and dyes, label and detect exosomal surface markers, enabling the characterization of exosome cargo. This is crucial for diagnostics, particularly in identifying biomarkers for diseases like cancer, neurodegenerative disorders, and cardiovascular conditions. 
For instance, in July 2023, Shimadzu Corporation developed Exorapid-qIC, an immunochromatography kit for extracellular vesicles (CD9) launched by Dai Nippon Toryo Co., Ltd., it is the world's first kit targeting exosomes. The kit includes gold nanoplate-labeled antibodies, immunochromatography test paper, and rinse solution. Shimadzu is responsible for detecting EV types and optimizing the detection system.
Market Geographical Analysis
North America is estimated to hold about 38.4% of the total market share throughout the forecast period
North America is estimated to hold about 38.4% of the total market share throughout the forecast period due to the rising government funding for the detection of new biomarkers and the increasing incidence of chronic conditions, such as cardiovascular diseases and cancer. In addition, growing research & development activities for the development of novel drugs, diagnostic methods, and treatment options are anticipated to drive the segment growth. 
For instance, in July 2024, Aruna Bio, a leader in neural exosome-based therapeutics for neurodegenerative conditions, received a US Patent No. 11,993,787 for its lead program, AB126, an exosome derived from neural stem cells. The patent, which extends protection covering the composition of matter for AB126 and products for gene therapy using AB16, is expected to be granted by 2038.
Market Segmentation
By Product Type
Kits and Reagents
Instruments
Others
By Application
Cancer Applications
Lung Cancer
Breast Cancer
Prostate Cancer
Colorectal Cancer
Other
Non-Cancer Applications
By End User
Diagnostics
Hospitals & Clinical Testing Laboratories
Others 
By Region
North America
U.S.
Canada
Mexico
Europe
Germany
UK
France
Italy
Spain
Rest of Europe
South America
Brazil
Argentina
Rest of South America
Asia-Pacific
China
India
Japan
South Korea
Rest of Asia-Pacific
Middle East and Africa
Market Competitive Landscape
The major global players in the market include STARTEK Health, Diagenode Inc., Fujifilm Holdings Corporation, Hitachi Chemical Diagnostics Inc., Lonza, MBL International, Miltenyi Biotec, Novus Biologicals, Qiagen, Thermo Fisher Scientific Inc. among others.
Key Developments
In January 2024, EXO Biologics SA, a Belgian biotech company committed to developing biopharmaceuticals using exosomes to treat rare diseases with high unmet medical needs, launched ExoXpert, a contract development and manufacturing organization (CDMO) specializing in exosomes. ExoXpert offers an MSC-based exosome manufacturing platform used in European clinical trials and is a wholly-owned subsidiary of EXO Biologics. 
Why Purchase the Report?
To visualize the global exosomes market segmentation based on product type, application, end-user, and region as well as understand key commercial assets and players.
Identify commercial opportunities by analyzing trends and co-development. 
Excel data sheet with numerous data points of the exosomes market level with all segments.
PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
Product mapping available as excel consisting of key products of all the major players.
The global exosomes market report would provide approximately 64 tables, 61 figures, and 186 pages.
Target Audience 2024
Manufacturers/ Buyers
Industry Investors/Investment Bankers
Research Professionals
Emerging Companies

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Table of Contents

1. Methodology and Scope
1.1. Research Methodology
1.2. Research Objective and Scope of the Report
2. Definition and Overview
3. Executive Summary
3.1. Snippet by Product Type
3.2. Snippet by Application
3.3. Snippet by End User
3.4. Snippet by Region
4. Dynamics
4.1. Impacting Factors
4.1.1. Drivers
4.1.1.1. Rise in the prevalence of cancer
4.1.1.2. Increasing focus on personalized medicine
4.1.2. Restraints
4.1.2.1. Technical complexity of exosome isolation and technological limitations
4.1.3. Opportunity
4.1.4. Impact Analysis
5. Industry Analysis
5.1. Porter's Five Force Analysis
5.2. Supply Chain Analysis
5.3. Pricing Analysis
5.4. Regulatory Analysis
5.5. Patent Analysis
5.6. PESTLE Analysis
5.7. SWOT Analysis
5.8. DMI Opinion
6. By Product Type
6.1. Introduction
6.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
6.1.2. Market Attractiveness Index, By Product Type
6.2. Kits and Reagents*
6.2.1. Introduction
6.3. Instruments
6.4. Others
7. By Application
7.1. Introduction
7.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
7.2. Market Attractiveness Index, By Application
7.3. Cancer Applications*
7.3.1. Introduction
7.3.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
7.4. Non-Cancer Applications
8. By End User
8.1. Introduction
8.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
8.1.2. Market Attractiveness Index, By End User
8.2. Diagnostics*
8.2.1. Introduction
8.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
8.3. Hospitals & Clinical Testing Laboratories
8.4. Others
9. By Region
9.1. Introduction
9.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Region
9.1.2. Market Attractiveness Index, By Region
9.2. North America
9.2.1. Introduction
9.2.2. Key Region-Specific Dynamics
9.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
9.2.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
9.2.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
9.2.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
9.2.6.1. U.S.
9.2.6.2. Canada
9.2.6.3. Mexico
9.3. Europe
9.3.1. Introduction
9.3.2. Key Region-Specific Dynamics
9.3.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
9.3.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
9.3.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
9.3.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
9.3.6.1. Germany
9.3.6.2. UK
9.3.6.3. France
9.3.6.4. Italy
9.3.6.5. Spain
9.3.6.6. Rest of Europe
9.4. South America
9.4.1. Introduction
9.4.2. Key Region-Specific Dynamics
9.4.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
9.4.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
9.4.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
9.4.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
9.4.6.1. Brazil
9.4.6.2. Argentina
9.4.6.3. Rest of South America
9.5. Asia-Pacific
9.5.1. Introduction
9.5.2. Key Region-Specific Dynamics
9.5.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
9.5.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
9.5.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
9.5.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
9.5.6.1. China
9.5.6.2. India
9.5.6.3. Japan
9.5.6.4. South Korea
9.5.6.5. Rest of Asia-Pacific
9.6. Middle East and Africa
9.6.1. Introduction
9.6.2. Key Region-Specific Dynamics
9.6.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
9.6.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
9.6.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
10. Competitive Landscape
10.1. Competitive Scenario
10.2. Market Positioning/Share Analysis
10.3. Mergers and Acquisitions Analysis
11. Company Profiles
11.1. STARTEK Health*
11.1.1. Company Overview
11.1.2. Product Portfolio and Description
11.1.3. Financial Overview
11.1.4. Key Developments
11.2. Diagenode Inc
11.3. Fujifilm Holdings Corporation
11.4. Hitachi Chemical Diagnostics Inc
11.5. Lonza
11.6. MBL International
11.7. Miltenyi Biotec
11.8. Novus Biologicals
11.9. Qiagen
11.10. Thermo Fisher Scientific Inc (*LIST NOT EXHAUSTIVE)
12. Appendix
12.1. About Us and Services
12.2. Contact Us