Summary

Overview
The Global Protein Crystallization Market reached US$ XX million in 2022 and is expected to reach US$ XX million by 2030, growing with a CAGR of XX% during the forecast period 2023-2030.
Protein crystals are organized molecular structures with a wide range of characteristics and great customizability. Their ability to self-assemble from components contained in cells lowers their environmental effect and drastically lowers the cost of manufacturing.
While protein crystals show promise as catalysts due to their ability to host a wide range of functional molecules, the methods now available only allow simple proteins and tiny molecules to connect to the crystals. Therefore, in order to fully utilize protein crystals for enzyme immobilization, methods for producing both natural enzymes and artificial functional molecules must be discovered.
The increasing need for biopharmaceuticals and novel medications has led to a greater need for protein crystallization, as it facilitates the knowledge of target protein structures and enhances drug development. Studies in structural biology depend on the crystallization of proteins. The need for tools and services related to protein crystallization has grown as a result of developments in this field.
Market Dynamics: Drivers
The Active Major Players
The active major players are driving the market. For instance, in August 2020, the National Institutes of Health (NIH) awarded the University of Arkansas for Medical Sciences (UAMS) a $10.6 million grant.
In October 2021, Absci Corporation, a drug and target discovery company that uses artificial intelligence (AI) and deep learning to extend the therapeutic potential of proteins, and EQRx, a new kind of pharmaceutical company dedicated collaborated to creating and providing significant new medicines to patients at drastically reduced prices.
In July 2023, Tokyo Tech researchers demonstrated that in-cell engineering can be a potent method for creating functional protein crystals with intriguing catalytic capabilities. The scientists created hybrid solid catalysts for synthetic photosynthesis using genetically engineered bacteria as an eco-friendly synthesis platform. These catalysts demonstrate great activity, stability, and durability, underscoring the potential benefits of the novel strategy that has been suggested.
High cost
Since protein crystallization can be costly and time-consuming, not all companies or researchers will use it substantially. It can be difficult to obtain high-quality crystals due to the intricate and technically demanding nature of the protein crystallization process. Alternative methods of structural biology, such as cryo-electron microscopy (cryo-EM), are becoming more and more popular and could pose a threat to conventional protein crystallization techniques.
Segment Analysis
The global protein crystallization market is segmented based on product type, technology, end-user and region.
The instruments segment accounted for approximately 45.7% of the market share
Instruments for protein crystallization are specialized tools and equipment used to help generate high-quality protein crystals. These tools are essential for applications in scientific research, medication development, and structural biology. These instruments are intended to be both flexible and helpful for particular manipulations of crystallization.
Creative Biostructure provides the most qualified crystal growing, handling, and seeding tools for customers. The tiniest precision devices for scientific research activity are toolsets. These instruments are proportionately appropriate for crystallization investigations involving both macromolecules and small molecules. They are simple to maintain so users can use them again later. In addition, with its accuracy, speed, and precision, the Crystal Phoenix is the best protein crystallography dispenser available. It is the ideal tool for sitting drop, hanging drop, and microbatch reactions.
Geographical Analysis
North America accounted for approximately 43.6% of the market share
North America has been a dominant force in the global protein crystallization market. The discovery of novel medications has been led by the biopharmaceutical sector in the United States for over three decades, and PhRMA member businesses remain at the forefront of this effort. An estimated $122 billion was spent on R&D by the whole US biopharmaceutical industry in 2020.
In large part due to continuous federal financing and fervent campaigning in the US, biomedical research has reached this point in the world. The nation's STEM education system and varied talent pipeline have been improved by the biopharmaceutical industry's enormous and ongoing commitment to motivating and nurturing the next generation of scientists, engineers, and technology professionals.
More than 6,000 biotech and life sciences companies call Texas home, including the Fortune 500 corporations McKesson, Tenet Healthcare, and Kimberly-Clark. The following companies have major operations in the state: Johnson & Johnson (J&J), Merck, Novartis, Abbott, Allergan, Lonza, and Galderma. In addition, Texas is home to six of the top 100 medical schools in the US and $6.6 billion in R&D spending annually.
The distribution and positioning of industries and clusters within an area are determined by the real estate, talent, and financial incentives provided by the local community. These areas of concentration are spreading and, crucially, have room to grow further in Minnesota, Texas, and Wisconsin.
COVID-19 Impact Analysis
The outbreak of the COVID-19 pandemic in late 2019 created unprecedented challenges for industries worldwide, including the global protein crystallization market. Lockdowns and social distancing tactics resulted in the temporary closure of numerous research organizations and laboratories, or in their capacity being decreased. As a result, both new research projects and ongoing protein crystallization investigations were put on hold.
In several areas, the pandemic's economic effects had an impact on research funding. Research groups may not have been able to invest as much in services, equipment, and investigations related to protein crystallization due to financial constraints.
By Product Type
• Instruments
o Liquid Handling Instruments
o Crystal Imaging Instruments
• Consumables
o Reagents & Kits/Screens
o Micro Plates
o Others
• Software & Services
By Technology
• X-ray Crystallography
• Cryo-electron Microscopy
• NMR Spectroscopy
• Others
By End-User
• Pharmaceutical and biotechnology companies
• Academic and Research Institutes
• Others
By Region
• North America
o U.S.
o Canada
o Mexico
• Europe
o Germany
o UK
o France
o Italy
o Spain
o Rest of Europe
• South America
o Brazil
o Argentina
o Rest of South America
• Asia-Pacific
o China
o India
o Japan
o Australia
o Rest of Asia-Pacific
• Middle East and Africa
Competitive Landscape
The major global players in the market include METTLER TOLEDO, Corning Incorporated, Greiner Bio-One International GmbH, HAMPTON RESEARCH CORP, Jena Bioscience GmbH, Bruker, Creative Proteomics, Molecular Dimensions among others.
Key Developments
• In January 2023, Novo Holdings, a worldwide life science investor invested $40 million in proteomics Technology company Evosep to expand clinical proteomics applications. The money will be used by Evosep to expand the proteomics applications made possible by its platform of standardized liquid chromatography.
Why Purchase the Report?
• To visualize the global protein crystallization market segmentation based on product type, technology, end-user and region as well as understand key commercial assets and players.
• Identify commercial opportunities by analyzing trends and co-development.
• Excel data sheet with numerous data points of protein crystallization market-level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as excel consisting of key products of all the major players.
The global protein crystallization market report would provide approximately 61 tables, 57 figures, and 186 Pages.
Target Audience 2023
• Manufacturers/ Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies

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Table of Contents

1. Methodology and Scope
1.1. Research Methodology
1.2. Research Objective and Scope of the Report
2. Definition and Overview
3. Executive Summary
3.1. Snippet by Product Type
3.2. Snippet by Technology
3.3. Snippet by End-User
3.4. Snippet by Region
4. Dynamics
4.1. Impacting Factors
4.1.1. Drivers
4.1.1.1. The Active Major Players
4.1.1.2. XX
4.1.2. Restraints
4.1.2.1. High Cost
4.1.2.2. XX
4.1.3. Opportunity
4.1.4. Impact Analysis
5. Industry Analysis
5.1. Porter's Five Force Analysis
5.2. Supply Chain Analysis
5.3. Pricing Analysis
5.4. Regulatory Analysis
5.5. SWOT Analysis
5.6. Patent Analysis
5.7. DMI Opinion
6. COVID-19 Analysis
6.1. Analysis of COVID-19
6.1.1. Scenario Before COVID
6.1.2. Scenario During COVID
6.1.3. Scenario Post COVID
6.2. Pricing Dynamics Amid COVID-19
6.3. Demand-Supply Spectrum
6.4. Government Initiatives Related to the Market During Pandemic
6.5. Manufacturers Strategic Initiatives
6.6. Conclusion
7. By Product Type
7.1. Introduction
7.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
7.1.2. Market Attractiveness Index, By Product Type
7.2. Instruments*
7.2.1. Introduction
7.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
7.3. Liquid Handling Instruments
7.4. Crystal Imaging Instruments
7.5. Consumables
7.6. Reagents & Kits/Screens
7.7. Micro Plates
7.8. Others
7.9. Software & Services
8. By Technology
8.1. Introduction
8.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Technology
8.1.2. Market Attractiveness Index, By Technology
8.2. X-ray Crystallography*
8.2.1. Introduction
8.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
8.3. X-ray Crystallography
8.4. Cryo-electron Microscopy
8.5. NMR Spectroscopy
8.6. Others
9. By End-User
9.1. Introduction
9.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
9.1.2. Market Attractiveness Index, By End-User
9.2. Pharmaceutical and Bio Technology Companies*
9.2.1. Introduction
9.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
9.3. Academic And Research Institutes
10. By Region
10.1. Introduction
10.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Region
10.1.2. Market Attractiveness Index, By Region
10.2. North America
10.2.1. Introduction
10.2.2. Key Region-Specific Dynamics
10.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
10.2.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Technology
10.2.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
10.2.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
10.2.6.1. U.S.
10.2.6.2. Canada
10.2.6.3. Mexico
10.3. Europe
10.3.1. Introduction
10.3.2. Key Region-Specific Dynamics
10.3.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
10.3.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Technology
10.3.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
10.3.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
10.3.6.1. Germany
10.3.6.2. UK
10.3.6.3. France
10.3.6.4. Italy
10.3.6.5. Spain
10.3.6.6. Rest of Europe
10.4. South America
10.4.1. Introduction
10.4.2. Key Region-Specific Dynamics
10.4.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
10.4.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Technology
10.4.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
10.4.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
10.4.6.1. Brazil
10.4.6.2. Argentina
10.4.6.3. Rest of South America
10.5. Asia-Pacific
10.5.1. Introduction
10.5.2. Key Region-Specific Dynamics
10.5.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
10.5.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Technology
10.5.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
10.5.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
10.5.6.1. China
10.5.6.2. India
10.5.6.3. Japan
10.5.6.4. Australia
10.5.6.5. Rest of Asia-Pacific
10.6. Middle East and Africa
10.6.1. Introduction
10.6.2. Key Region-Specific Dynamics
10.6.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Product Type
10.6.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Technology
10.6.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End-User
11. Competitive Landscape
11.1. Competitive Scenario
11.2. Market Positioning/Share Analysis
11.3. Mergers and Acquisitions Analysis
12. Company Profiles
12.1. Rigaku Corporation*
12.1.1. Company Overview
12.1.2. Product Portfolio and Description
12.1.3. Financial Overview
12.1.4. Key Developments
12.2. FORMULATRIX
12.3. METTLER TOLEDO
12.4. Corning Incorporated
12.5. Greiner Bio-One International GmbH
12.6. HAMPTON RESEARCH CORP
12.7. Jena Bioscience GmbH
12.8. Bruker
12.9. Creative Proteomics
12.10. Molecular Dimensions
LIST NOT EXHAUSTIVE
13. Appendix
13.1. About Us and Services
13.2. Contact Us