Summary

Overview
Global Pressure-Volume Loop Systems Market reached US$ XX million in 2022 and is expected to reach US$ XX million by 2030, growing with a CAGR of XX % during the forecast period 2023-2030.
Pressure-volume loops are graphs which shows the changing relationship between left ventricular pressure and volume during a cardiac cycle. They provide useful information such as stroke volume or end-diastolic volume, as well as systolic, diastolic, and pulse pressure. PV loops provide insights into all aspects of heart function, which has proven to be invaluable for cardiac research, clinical diagnoses, and improving the intra-operative experience for select cardiac interventions where comprehensive quantitative data is needed.
Market Dynamics: Drivers and Restraints
Rise in the advancements in pressure-volume loop systems
Recent advancements in the field through the use of admittance instead of the older conductance technology, Transonic Scisense PV Catheters incorporate the latest admittance technology and high-fidelity pressure sensors to meet the stringent demands of cardiovascular research.
Catheters are used with the advantage pressure-volume system, a significant technical advancement in the field of animal cardiac function research. It is the only catheter-based system to accurately quantify true ventricular volume in real time using admittance technology. The advantage system Phase signal provides real-time feedback about the Catheter position to ensure quality measurements from every procedure.
Furthermore, the global pressure-volume loop systems market is also driven by various factors like, increasing cardiovascular diseases, rise in healthcare expenditure, research and development initiatives and others that help the market to grow during the forecast period.
Market Dynamics: Restraint
Pressure-volume loop Systems (PV loops) are a costly diagnostic tool, particularly for smaller healthcare facilities and research organizations with limited budgets. They require specific expertise and training, making clinical adoption limited. Additionally, PV loops face challenges in increasing market share due to the prevalence of other diagnostic techniques like echocardiography and conventional catheterization, which are more widely used.
Segment Analysis
The global pressure-volume loop systems market is segmented based on parameter, application, end-user and region.
The contractility index (ESPVR) segment from the parameter segment accounted for approximately 40.5% of the pressure-volume loop systems market share
The contractility index (ESPVR) segment from the parameter segment accounted for approximately 40.5% and is expected to be dominated during the forecast period. The end-systolic pressure-volume relationship represents the maximal pressure developed by the LV at any given volume and is a measure of cardiac contractility. The slope of ESPVR, also referred to as Ees, is an index of end-systolic elastance and provides information on contractile function.
Cardiac contractility is the innate ability of the heart muscle (cardiac muscle or myocardium) to contract, independent of preload. Therefore, a change in Ees can be viewed as a change in contractility.
Geographical Analysis
North America accounted for approximately 38.4% of the market share in 2022
North America is estimated to hold about 38.4% of the total market share throughout the forecast period, owing to the increasing research and development activities in this field, the growing prevalence of heart diseases, and technological advancements in the healthcare industry.
For instance, in June 2023, Medical devices manufacturer Millar planned to advance its pressure-volume (PV) loop technology by combining its catheter solutions with Transonic Scisense’s Admittance-based PV loop systems. To support the exit of Transonic Scisense from the life sciences market, Millar has agreed to build replacement solutions for the former customers.
COVID-19 Impact Analysis
The COVID-19 pandemic had a substantial impact on global pressure-volume loop systems market. For instance, A study published in Annals of Intensive Care examined the relationship between the hysteresis of the pressure-volume curve and the recruitment-to-inflation ratio in patients with COVID-19. The study found that airway closure occurs even with a pressure-constant, quasi-static PV curve.
Market Segmentation
By Parameter
• Contractility Index (ESPVR)
• Elastance (EDPVR)
• Cardiac Output
• Stroke Volume
• Max and Min Ventricular dP/dt
• Others
By Application
• Baseline PV loop analysis
• Occlusion PV loop analysis
• Phenotyping gene manipulations
• Cardiac hypertrophy
• Cardiac failure
• Others
By End User
• Contract Research Organization
• Pharmaceutical and Biotechnology Companies
• Others
By Region
• North America
o U.S.
o Canada
o Mexico
• Europe
o Germany
o UK
o France
o Italy
o Spain
o Rest of Europe
• South America
o Brazil
o Argentina
o Rest of South America
• Asia-Pacific
o China
o India
o Japan
o Australia
o Rest of Asia-Pacific
• Middle East and Africa
Competitive Landscape
The major global players in the market include Millor Inc, Edwards Lifesciences, Abbott Laboratories, Medtronic, GE Healthcare, Philips Healthcare, LiDCO, PiCCO, PulseCath, EMKATECHNOLOGIES and others.
Key Developments
 In June 2023, Millar, the industry leader in research pressure measurements and global OEM solutions partner, stated that it will be guiding pressure-volume (PV) loop technology into the future by combining its market-leading catheter solutions with Transonic Scisense's Admittance-based pressure-volume (PV) loop systems.
Why Purchase the Report?
• To visualize the global pressure-volume loop systems market segmentation based on parameter, application, end user and region as well as understand key commercial assets and players.
• Identify commercial opportunities by analysing trends and co-development.
• Excel data sheet with numerous data points of pressure-volume loop systems market-level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as excel consisting of key products of all the major players.
The global pressure-volume loop systems market report would provide approximately 77 tables, 79 figures and 187 Pages.
Target Audience 2023
• Manufacturers/ Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies

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Table of Contents

1. Methodology and Scope
1.1. Research Methodology
1.2. Research Objective and Scope of the Report
2. Definition and Overview
3. Executive Summary
3.1. Snippet by Parameter
3.2. Snippet by Application
3.3. Snippet by End User
3.4. Snippet by Region
4. Market Dynamics
4.1. Impacting Factors
4.1.1. Drivers
4.1.1.1. Rise in the advancements in pressure-volume loop systems
4.1.1.2. Increasing cardiovascular diseases
4.1.2. Restraints
4.1.2.1. High cost of equipment
4.1.3. Opportunity
4.1.4. Impact Analysis
5. Industry Analysis
5.1. Porter's Five Force Analysis
5.2. Supply Chain Analysis
5.3. Pricing Analysis
5.4. Regulatory Analysis
5.5. Unmet Needs
5.6. DMI Opinion
6. COVID-19 Analysis
6.1. Analysis of COVID-19
6.1.1. Scenario Before COVID
6.1.2. Scenario During COVID
6.1.3. Scenario Post COVID
6.2. Pricing Dynamics Amid COVID-19
6.3. Demand-Supply Spectrum
6.4. Government Initiatives Related to the Market During Pandemic
6.5. Manufacturers Strategic Initiatives
6.6. Conclusion
7. By Parameter
7.1. Introduction
7.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Parameter
7.1.2. Market Attractiveness Index, By Parameter
7.2. Contractility Index (ESPVR)*
7.2.1. Introduction
7.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
7.3. Elastance (EDPVR)
7.4. Cardiac Output
7.5. Stroke Volume
7.6. Max and Min Ventricular dP/dt
7.7. Others
8. By Application
8.1. Introduction
8.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
8.1.2. Market Attractiveness Index, By Application
8.2. Baseline PV loop analysis *
8.2.1. Introduction
8.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
8.3. Occlusion PV loop analysis
8.4. Phenotyping gene manipulations
8.5. Cardiac hypertrophy
8.6. Cardiac failure
8.7. Others
9. By End User
9.1. Introduction
9.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
9.1.2. Market Attractiveness Index, By End User
9.2. Contract Research Organization*
9.2.1. Introduction
9.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
9.3. Pharmaceutical and Biotechnology Companies
9.4. Others
10. By Region
10.1. Introduction
10.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Region
10.1.2. Market Attractiveness Index, By Region
10.2. North America
10.2.1. Introduction
10.2.2. Key Region-Specific Dynamics
10.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Parameter
10.2.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
10.2.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
10.2.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
10.2.6.1. U.S.
10.2.6.2. Canada
10.2.6.3. Mexico
10.3. Europe
10.3.1. Introduction
10.3.2. Key Region-Specific Dynamics
10.3.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Parameter
10.3.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
10.3.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
10.3.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
10.3.6.1. Germany
10.3.6.2. UK
10.3.6.3. France
10.3.6.4. Italy
10.3.6.5. Spain
10.3.6.6. Rest of Europe
10.4. South America
10.4.1. Introduction
10.4.2. Key Region-Specific Dynamics
10.4.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Parameter
10.4.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
10.4.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
10.4.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
10.4.6.1. Brazil
10.4.6.2. Argentina
10.4.6.3. Rest of South America
10.5. Asia-Pacific
10.5.1. Introduction
10.5.2. Market Size Analysis and Y-o-Y Growth Analysis (%), By Parameter
10.5.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
10.5.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
10.5.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
10.5.5.1. China
10.5.5.2. India
10.5.5.3. Japan
10.5.5.4. Australia
10.5.5.5. Rest of Asia-Pacific
10.6. Middle East and Africa
10.6.1. Introduction
10.6.2. Key Region-Specific Dynamics
10.6.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Parameter
10.6.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
10.6.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
11. Competitive Landscape
11.1. Competitive Scenario
11.2. Market Positioning/Share Analysis
11.3. Mergers and Acquisitions Analysis
12. Company Profiles
12.1. Millor Inc*
12.1.1. Company Overview
12.1.2. Product Portfolio and Description
12.1.3. Financial Overview
12.1.4. Key Developments
12.2. Edwards Lifesciences
12.3. Abbott Laboratories
12.4. Medtronic
12.5. GE Healthcare
12.6. Philips Healthcare
12.7. LiDCO
12.8. PiCCO
12.9. PulseCath
12.10. EMKATECHNOLOGIES
LIST NOT EXHAUSTIVE
13. Appendix
13.1. About Us and Services
13.2. Contact Us