Summary
Japan Hematopoietic Stem Cell Transplantation Market was valued at USD 121.03 Million in 2024 and is expected to reach USD 176.18 Million by 2030 with a CAGR of 6.42% during the forecast period. The Japan Hematopoietic Stem Cell Transplantation (HSCT) market is primarily driven by several key factors. Advances in medical technology and increased research into stem cell therapies have significantly improved treatment outcomes, making HSCT a viable option for a range of hematological disorders. Japan's aging population is contributing to a higher incidence of conditions such as leukemia and lymphoma, thus boosting demand for these treatments. Government support through healthcare policies and funding for research also plays a crucial role in market growth. The rise in awareness and acceptance of HSCT as a standard treatment option, along with the development of more targeted and less invasive transplant techniques, continues to drive market expansion.
Key Market Drivers
Rising Incidence of Hematological Disorders
Japan's demographic landscape is characterized by one of the oldest populations globally, with a substantial proportion of its citizens aged 65 and over. This aging trend has profound implications for healthcare, particularly concerning age-related diseases and conditions. As the population ages, there is a marked increase in the prevalence of chronic and complex health issues, including various hematological disorders such as leukemia, lymphoma, and multiple myeloma. These diseases are particularly prevalent among the elderly due to age-related changes in immune function and the cumulative effects of environmental and genetic factors over a lifetime. According to a study titled, “Differences in incidence and trends of haematological malignancies in Japan and the United States”, this was the first comprehensive study to assess the incidence of hematological malignancies among Asians using population-based data. The findings reveal notable differences in disease incidence and trends between Japan and the US. While Japan exhibits a lower overall incidence of hematological malignancies compared to the US, there is a significant upward trend, particularly for myeloid leukemia (ML). The study suggests that there may be distinct etiological factors contributing to these diseases, indicating that further epidemiological research by disease subtypes—taking into account genetic and environmental differences—will be valuable for understanding tumorigenesis.
The rising incidence of these hematological conditions among Japan’s elderly population creates a heightened demand for effective treatment options. Hematopoietic Stem Cell Transplantation (HSCT) has emerged as a critical and often life-saving therapeutic approach for managing these diseases. HSCT involves the infusion of healthy stem cells to replace damaged or diseased bone marrow, providing a potential cure or significant disease management for conditions that are otherwise difficult to treat, particularly in older adults.
One of the challenges with treating older patients is their often complex health profiles. The elderly frequently present with multiple comorbidities, which can complicate treatment plans and increase the risk of adverse outcomes. As a result, there is a need for advanced treatment modalities that can address these complexities while offering effective disease management. HSCT fits this requirement as it provides a comprehensive approach to treating severe hematological disorders, potentially reversing the underlying disease processes that have become resistant to conventional therapies. Advancements in HSCT techniques and supportive care have made the procedure increasingly viable for older patients. Innovations such as improved stem cell processing, refined conditioning regimens, and better management of transplant-related complications have enhanced the safety and efficacy of HSCT. These developments make HSCT a more attractive option for elderly patients, contributing to its growing adoption and driving market expansion.
Enhanced Supportive Care and Post-Transplant Therapies
Supportive care and post-transplant therapies have undergone transformative advancements that have significantly enhanced the success rates of Hematopoietic Stem Cell Transplantation (HSCT) procedures. These improvements have played a crucial role in mitigating risks, improving patient outcomes, and driving the growth of the Japan Hematopoietic Stem Cell Transplantation Market. One of the critical areas of improvement in supportive care for HSCT patients is infection control. Given that HSCT recipients are immunocompromised due to both the underlying disease and the intensive conditioning regimens, they are highly susceptible to infections. Advanced infection control measures now include sophisticated antimicrobial prophylaxis strategies, which are tailored to the specific risks of individual patients. This includes the use of broad-spectrum antibiotics, antifungal agents, and antiviral medications to preemptively address potential infections.
Innovations in environmental controls, such as high-efficiency particulate air (HEPA) filtration systems and sterile barrier techniques, are implemented to reduce the risk of nosocomial infections. The development of rapid diagnostic tools allows for early detection of infections, enabling prompt and targeted treatment, which is crucial for preventing severe complications and improving survival rates.
Graft-versus-host disease (GVHD) is a significant complication of HSCT, where the donor’s immune cells attack the recipient’s tissues. Advances in the management of GVHD have markedly improved patient outcomes. Newer immunosuppressive therapies, such as targeted monoclonal antibodies and small-molecule inhibitors, offer more precise control of the immune response while minimizing systemic toxicity. Personalized approaches to GVHD prevention and treatment have become more prevalent. For example, genetic profiling of both donor and recipient can help predict the likelihood of GVHD and tailor prophylactic strategies accordingly. Innovations in cell therapies, such as the use of T-cell depletion techniques, help reduce the incidence and severity of GVHD, contributing to better overall transplant outcomes.
Increased Investment from Private Sector
Private sector investment plays a pivotal role in driving the growth and development of the Hematopoietic Stem Cell Transplantation (HSCT) market in Japan. This sector includes biotech companies, pharmaceutical firms, and private investors, all of whom are making substantial contributions to the advancement of HSCT technologies and services.
Private sector investment is crucial for funding research and development (R&D) in HSCT. Biotech and pharmaceutical companies are investing in cutting-edge research to develop novel stem cell therapies and improve existing treatment modalities. This investment supports a wide range of activities, from basic research on stem cell biology to the development of new therapeutic strategies and clinical trials. The financial backing provided by private entities enables researchers to explore innovative approaches, such as genetic modification of stem cells, to address previously untreatable conditions. For example, advancements in genome editing technologies like CRISPR-Cas9 are made possible through private investment, leading to potential breakthroughs in personalized stem cell therapies.
Investment from the private sector is instrumental in the development of new technologies that enhance the capabilities of HSCT procedures. This includes advancements in stem cell processing technologies, such as automated cell separators and improved cryopreservation techniques, which ensure the purity and viability of stem cell grafts. Private companies are also working on the development of novel conditioning regimens and supportive care technologies that reduce the risk of complications and improve patient outcomes. These innovations are critical for making HSCT procedures safer and more effective, especially as the patient population becomes more diverse and complex.
Collaboration between Healthcare Providers and Research Institutions
Collaboration between healthcare providers and research institutions is essential for the advancement of HSCT therapies and market growth. In Japan, partnerships between hospitals, research centers, and universities facilitate the exchange of knowledge, resources, and expertise. These collaborations enable the implementation of the latest research findings into clinical practice, leading to the development of more effective HSCT treatments. Joint initiatives also promote the sharing of data and best practices, contributing to improved patient outcomes and more efficient treatment protocols. The synergy between clinical and research communities drives innovation in HSCT and supports the expansion of the market by ensuring that new therapies and technologies are rapidly translated into practice.
Key Market Challenges
High Cost of Hematopoietic Stem Cell Transplantation (HSCT)
One of the most significant challenges facing the Hematopoietic Stem Cell Transplantation (HSCT) market in Japan is the high cost associated with the procedure. The financial burden of HSCT is multifaceted, encompassing the expenses of pre-transplant conditioning, the transplant procedure itself, and post-transplant care. These costs can be prohibitive for many patients and healthcare systems, affecting accessibility and equity in treatment. The costs begin with pre-transplant conditioning regimens, which involve intensive chemotherapy or radiation to prepare the patient’s body for the stem cell infusion. This preparatory phase is crucial but adds significant expenses due to the need for specialized drugs and monitoring. The transplant procedure involves complex processes such as stem cell collection, processing, and infusion, all of which require advanced technologies and skilled medical personnel. Each step of this process incurs costs related to medical equipment, hospital stays, and professional fees.
Post-transplant care further contributes to the overall expense. Patients require extended hospitalization and close monitoring to manage potential complications such as infections, graft-versus-host disease (GVHD), and other side effects. Long-term follow-up care, including routine check-ups and ongoing medication, adds to the financial burden. For many patients, especially those without adequate insurance coverage, these costs can be overwhelming. The cost issue extends to healthcare systems and insurance providers, who must balance the financial implications of HSCT with their resources and budgets. The high costs can strain public and private health insurance systems, potentially leading to increased premiums or limited coverage options. This financial pressure may influence the availability of HSCT services and contribute to disparities in access, particularly for patients in lower-income or rural areas.
Limited Donor Availability
Another significant challenge in the Japan Hematopoietic Stem Cell Transplantation Market is the limited availability of suitable stem cell donors. HSCT often requires a matching donor to provide healthy stem cells, which can be a major hurdle in finding compatible matches, especially for patients with rare or complex genetic profiles. The process of finding a matching donor involves complex tissue typing to ensure compatibility between the donor and recipient. This compatibility is crucial for minimizing the risk of rejection and other complications. However, the pool of potential donors is limited, and finding a match can be particularly challenging for patients from minority or diverse ethnic backgrounds.
In Japan, the situation is further complicated by the relatively small size of the national stem cell donor registry compared to other countries with larger populations. Although Japan has made significant strides in expanding its donor registry, the need for more extensive and diverse registries remains critical. Expanding the donor pool involves increasing the number of registered donors and ensuring that the registry reflects the genetic diversity of the population. Efforts to address the donor shortage include initiatives to recruit more donors, particularly from underrepresented ethnic groups, to improve the likelihood of finding matches. International collaboration and participation in global registries can also enhance access to a broader pool of potential donors. Advancements in stem cell research, such as the development of stem cell banking and the use of induced pluripotent stem cells (iPSCs), offer potential solutions to mitigate donor shortages in the future.
Key Market Trends
Technological Advancements in Stem Cell Therapies
Technological advancements have profoundly reshaped the field of Hematopoietic Stem Cell Transplantation (HSCT), leading to significant improvements in its effectiveness and safety. In Japan, a country known for its commitment to medical innovation, several key advancements have been instrumental in transforming HSCT procedures and outcomes.
One of the major breakthroughs in HSCT is the enhancement of stem cell processing techniques. Modern automated cell processing systems have revolutionized the preparation and quality control of stem cell grafts. These systems automate the separation, purification, and collection of stem cells, minimizing human error and reducing the risk of contamination. Automated cell processing not only ensures higher purity and viability of stem cells but also streamlines the overall workflow, making the process more efficient and reproducible. The precision of these systems enhances the quality of the stem cell grafts, which directly contributes to better patient outcomes. By providing a more reliable and standardized product, these advancements help improve the success rates of HSCT procedures. The ability to process stem cells with greater accuracy supports the development of more personalized treatment approaches, tailored to the specific needs of each patient. Graft preservation is another area where technological advancements have made a significant impact. Improved cryopreservation techniques are crucial for the long-term storage of stem cells, allowing for their use in transplants even if the procedures are delayed. Innovations in cryoprotectants and freezing protocols have enhanced the viability and functionality of preserved stem cells.
Pre-transplant conditioning regimens are designed to prepare the patient’s body for the HSCT procedure by eradicating diseased cells and suppressing the immune system to prevent rejection. Technological advancements have led to the development of more sophisticated conditioning regimens, including targeted therapies and less toxic agents. The use of novel conditioning agents and regimens allows for more precise targeting of malignant cells while minimizing damage to healthy tissues. This targeted approach reduces the risk of complications and improves the overall safety of the procedure. Personalized conditioning regimens, based on individual patient characteristics and disease profiles, contribute to better treatment outcomes and enhanced patient safety.
Expanding Research and Development Activities
Ongoing research and development (R&D) activities are fundamental drivers of the Hematopoietic Stem Cell Transplantation (HSCT) market in Japan, shaping the future of this critical medical field. Continuous investment in various facets of research, including clinical trials, basic science, and translational studies, plays a pivotal role in advancing HSCT technologies and improving patient care. In Japan, renowned research institutions and pharmaceutical companies are actively engaged in pioneering work that pushes the boundaries of HSCT. This includes discovering novel treatment modalities, refining transplant techniques, and developing innovative patient management strategies. Japanese research efforts are particularly notable for their focus on creating more effective and safer stem cell therapies. This involves exploring new approaches to stem cell processing, optimizing pre-transplant conditioning regimens, and improving graft preservation methods. According to a study titled, “Unit selection for umbilical cord blood transplantation for adults with acute myeloid leukemia in complete remission: a Japanese experience” to explore the optimal criteria for selecting umbilical cord blood units (UCB) for transplantation, we conducted a registry-based study involving 1,355 adults with acute myeloid leukemia in first or second complete remission who received single-unit UCB transplants. For inclusion in the analysis, UCB units were required to have a total nucleated cell (TNC) dose of at least 2.0 × 10^7/kg and a minimum 4/6 match for HLA-A, -B, and -DR antigens, reflecting the less stringent criteria used in Japan compared to Western countries. Our findings indicated that neither TNC dose nor the degree of HLA matching significantly impacted survival (P = 0.138 and P = 0.696, respectively). Although better HLA matching for HLA-A, -B antigens, and -DRB1 was linked to reduced non-relapse mortality (P = 0.011) and increased relapse (P = 0.046), it did not lead to improved overall survival (P = 0.680). Considering HLA-A, -B, and -DRB1 at the allele level proved less effective for predicting non-relapse mortality (P = 0.198). These results suggest that Japan’s less stringent UCB unit selection criteria are appropriate and may even offer a better chance of finding suitable units for transplantation.
Clinical trials are a crucial component of this R&D landscape. They test new therapies and techniques in real-world settings, providing valuable data on their efficacy and safety. Investment in these trials helps validate new treatment approaches and facilitates their integration into clinical practice. As new therapies demonstrate promise in trials, they pave the way for their adoption in routine clinical care, leading to improved outcomes for patients. Basic research lays the foundation for these advancements by deepening our understanding of stem cell biology and the mechanisms underlying hematological disorders. Insights gained from this research inform the development of targeted therapies and personalized treatment plans. For example, breakthroughs in genetic research may lead to the creation of new stem cell therapies that address specific genetic mutations associated with various blood cancers.
Segmental Insights
Therapy Insights
Based on the Therapy, allogeneic HSCT is currently the dominant approach over autologous HSCT due to a combination of disease-specific factors, donor availability, and advancements in transplant techniques. Allogeneic HSCT involves using stem cells from a healthy donor, which can be a relative or an unrelated individual. This method is particularly effective for treating aggressive hematological malignancies such as leukemia, lymphoma, and myelodysplastic syndromes. The primary advantage of allogeneic HSCT lies in the graft-versus-leukemia (GVL) effect, where the donor’s immune cells attack residual cancer cells, reducing the risk of relapse. This immunological benefit is crucial for high-risk or relapsed cancers, making allogeneic HSCT a preferred choice for these conditions. Autologous HSCT, which utilizes the patient’s own stem cells, is typically used for diseases like multiple myeloma and some types of lymphoma. However, it lacks the GVL effect, which limits its efficacy for certain high-risk hematological malignancies. For patients with more aggressive or relapsed diseases, the lack of this additional therapeutic benefit makes allogeneic HSCT a more favorable option.
The availability of suitable donors significantly influences the preference for allogeneic HSCT in Japan. The country boasts a well-established stem cell donor registry, supported by organizations such as the Japanese Bone Marrow Donor Program. This registry facilitates the identification of compatible donors for allogeneic transplants, providing a crucial resource for patients in need of a donor. In contrast, autologous HSCT relies on the patient’s ability to collect and preserve their own stem cells, which can be challenging for those with advanced disease or poor health. This limitation can make allogeneic HSCT a more viable option, especially for patients who cannot produce a sufficient quantity of their own stem cells.
Indication Insights
Based on Indication, leukemia is the dominant disorder driving the Japan Hematopoietic Stem Cell Transplantation Market. This prominence is due to several factors, including the high incidence of leukemia, the complex treatment needs associated with the disease, and the significant potential benefits of HSCT in managing and potentially curing this condition. Leukemia, encompassing several types of blood cancers characterized by the overproduction of abnormal white blood cells, is a major concern in Japan's healthcare system. The disease presents in various forms, including acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), and chronic myeloid leukemia (CML). The high incidence of these leukemia subtypes and their often-aggressive nature make them a primary focus for HSCT.
In Japan, leukemia is one of the most common hematological malignancies requiring HSCT due to its potential for relapse and resistance to conventional therapies. The complexity of treating leukemia, particularly in cases that are refractory or relapsed, drives the demand for HSCT as a more intensive and potentially curative treatment option. The ability of HSCT to offer a graft-versus-leukemia (GVL) effect, where the transplanted immune cells attack residual leukemia cells, is a crucial factor in its dominance. This therapeutic benefit can significantly improve outcomes for patients with high-risk or advanced forms of leukemia. HSCT is particularly effective for treating leukemia due to its potential to provide a comprehensive immune system reset. For patients with leukemia, especially those with aggressive or relapsed forms, HSCT offers a critical opportunity to achieve remission and potentially a cure. The process involves either autologous HSCT, where the patient’s own stem cells are used, or allogeneic HSCT, where stem cells from a donor are employed.
Regional Insights
The Kanto region emerges as the dominant area. The Kanto region, which includes major metropolitan areas such as Tokyo and Yokohama, plays a pivotal role in shaping the landscape of HSCT due to several key factors: its advanced medical infrastructure, concentration of specialized healthcare facilities, and a high population density that influences both demand and access to HSCT services. The Kanto region boasts some of the most advanced medical facilities and research institutions in Japan. Tokyo, as the capital city, is home to several leading hospitals and medical centers that specialize in HSCT. Institutions such as the National Cancer Center Hospital and the Keio University Hospital are renowned for their expertise in hematological disorders and stem cell transplantation. These facilities are equipped with cutting-edge technology and staffed by highly skilled professionals, which enhances the quality and availability of HSCT services.
The concentration of advanced medical infrastructure in Kanto facilitates not only the provision of HSCT but also the development and implementation of new techniques and protocols. Research institutions in the region contribute significantly to advancements in HSCT, including improvements in conditioning regimens, graft-versus-host disease (GVHD) management, and post-transplant care. This environment of innovation and excellence attracts patients from other regions seeking the best possible care, further solidifying Kanto’s dominance in the Japan Hematopoietic Stem Cell Transplantation Market. The Kanto region’s high population density, with Tokyo being one of the most populous cities in the world, significantly impacts the demand for HSCT services. A larger population base means a higher number of patients requiring advanced treatments for conditions such as leukemia, lymphoma, and other hematological disorders. This elevated demand drives the region’s healthcare system to maintain and expand HSCT services to meet the needs of a diverse and extensive patient population.
The concentration of patients in the Kanto region also contributes to a more robust and competitive market for HSCT. With a higher patient volume, healthcare providers in Kanto are incentivized to offer specialized services and maintain high standards of care. This competitive environment fosters continuous improvements in HSCT techniques and patient management strategies, enhancing the overall effectiveness of treatment and patient outcomes.
Key Market Players
• Healios K.K.
• FUJIFILM Corporation
• Lonza K.K.
• Merck Ltd.
• Sanofi K.K.
• Sartorius Japan K.K
• Takeda Pharmaceutical Company Limited
• Celaid Therapeutics Inc.
Report Scope:
In this report, the Japan Hematopoietic Stem Cell Transplantation Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:
• Japan Hematopoietic Stem Cell Transplantation Market, By Therapy:
o Allogenic
o Autologous
• Japan Hematopoietic Stem Cell Transplantation Market, By Indication:
o Lymphoproliferative Disorder
o Leukemia
o Non-Hodgkin lymphoma
o Hodgkin lymphoma
o Plasma cell disorders
o Others
• Japan Hematopoietic Stem Cell Transplantation Market, By Application:
o Bone Marrow Stem Cell Transplant
o Peripheral Blood Stem Cell Transplant
o Cord Blood Transplant
• Japan Hematopoietic Stem Cell Transplantation Market, By End User:
o Hospitals
o Specialty Clinics
o Others
• Japan Hematopoietic Stem Cell Transplantation Market, By Region:
o Hokkaido
o Tohoku
o Kanto
o Chubu
o Kansai
o Chugoku
o Shikoku
o Kyushu
Competitive Landscape
Company Profiles: Detailed analysis of the major companies present in the Japan Hematopoietic Stem Cell Transplantation Market.
Available Customizations:
Japan Hematopoietic Stem Cell Transplantation Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:
Company Information
• Detailed analysis and profiling of additional market players (up to five).
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Table of Contents
1. Product Overview
1.1. Market Definition
1.2. Scope of the Market
1.2.1. Markets Covered
1.2.2. Years Considered for Study
1.2.3. Key Market Segmentations
2. Research Methodology
2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validations
2.7. Assumptions and Limitations
3. Executive Summary
3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends
4. Voice of Customer
5. Japan Hematopoietic Stem Cell Transplantation Market Outlook
5.1. Market Size & Forecast
5.1.1. By Value
5.2. Market Share & Forecast
5.2.1. By Therapy (Allogenic, Autologous)
5.2.2. By Indication (Lymphoproliferative Disorder, Leukemia, Non-Hodgkin lymphoma, Hodgkin lymphoma, Plasma cell disorders and Others)
5.2.3. By Application (Bone Marrow Stem Cell Transplant, Peripheral blood stem cell transplant, and Cord blood transplant)
5.2.4. By End User (Hospitals, Specialty Clinics, and Others)
5.2.5. By Region
5.2.6. By Company (2024)
5.3. Market Map
6. Hokkaido Hematopoietic Stem Cell Transplantation Market Outlook
6.1. Market Size & Forecast
6.1.1. By Value
6.2. Market Share & Forecast
6.2.1. By Therapy
6.2.2. By Indication
6.2.3. By Application
6.2.4. By End User
7. Tohoku Hematopoietic Stem Cell Transplantation Market Outlook
7.1. Market Size & Forecast
7.1.1. By Value
7.2. Market Share & Forecast
7.2.1. By Therapy
7.2.2. By Indication
7.2.3. By Application
7.2.4. By End User
8. Kanto Hematopoietic Stem Cell Transplantation Market Outlook
8.1. Market Size & Forecast
8.1.1. By Value
8.2. Market Share & Forecast
8.2.1. By Therapy
8.2.2. By Indication
8.2.3. By Application
8.2.4. By End User
9. Chubu Hematopoietic Stem Cell Transplantation Market Outlook
9.1. Market Size & Forecast
9.1.1. By Value
9.2. Market Share & Forecast
9.2.1. By Therapy
9.2.2. By Indication
9.2.3. By Application
9.2.4. By End User
10. Kansai Hematopoietic Stem Cell Transplantation Market Outlook
10.1. Market Size & Forecast
10.1.1. By Value
10.2. Market Share & Forecast
10.2.1. By Therapy
10.2.2. By Indication
10.2.3. By Application
10.2.4. By End User
11. Chugoku Hematopoietic Stem Cell Transplantation Market Outlook
11.1. Market Size & Forecast
11.1.1. By Value
11.2. Market Share & Forecast
11.2.1. By Therapy
11.2.2. By Indication
11.2.3. By Application
11.2.4. By End User
12. Shikoku Hematopoietic Stem Cell Transplantation Market Outlook
12.1. Market Size & Forecast
12.1.1. By Value
12.2. Market Share & Forecast
12.2.1. By Therapy
12.2.2. By Indication
12.2.3. By Application
12.2.4. By End User
13. Kyushu Hematopoietic Stem Cell Transplantation Market Outlook
13.1. Market Size & Forecast
13.1.1. By Value
13.2. Market Share & Forecast
13.2.1. By Therapy
13.2.2. By Indication
13.2.3. By Application
13.2.4. By End User
14. Market Dynamics
14.1. Drivers
14.2. Challenges
15. Market Trends & Developments
15.1. Merger & Acquisition (If Any)
15.2. Product Launches (If Any)
15.3. Recent Developments
16. Japan Hematopoietic Stem Cell Transplantation Market: SWOT Analysis
17. Porter’s Five Forces Analysis
17.1. Competition in the Industry
17.2. Potential of New Entrants
17.3. Power of Suppliers
17.4. Power of Customers
17.5. Threat of Substitute Products
18. Competitive Landscape
18.1. Healios K.K.
18.1.1. Business Overview
18.1.2. Company Snapshot
18.1.3. Products & Services
18.1.4. Financials (As Reported)
18.1.5. Recent Developments
18.1.6. Key Personnel Details
18.1.7. SWOT Analysis
18.2. FUJIFILM Corporation
18.3. Lonza K.K.
18.4. Merck Ltd.
18.5. Sanofi K.K.
18.6. Sartorius Japan K.K
18.7. Takeda Pharmaceutical Company Limited
18.8. Celaid Therapeutics Inc.
19. Strategic Recommendations
20. About Us & Disclaimer