オルガノイド市場規模・予測（2020年～2030年）、世界・地域シェア、動向、成長機会分析レポート対象範囲臓器タイプ別（腸、肝臓、胃、膵臓、肺、脳、腎臓、その他）、用途別（生物疾患開発、感染症病態、再生医療、創薬・個別化医療、薬毒性・有効性試験、その他）、供給源別（多能性幹細胞、臓器特異的成体幹細胞）、タイプ別（器具、消耗品、サービス）、地域別

Organoids Market Size and Forecasts (2020 - 2030), Global and Regional Share, Trends, and Growth Opportunity Analysis Report Coverage: By Organ Type (Intestine, Liver, Stomach, Pancreas, Lung, Brain, Kidney, and Others), Application (Development of Biology Disease, Pathology of infectious Disease, Regenerative Medicines, Drug Discovery and Personalized Medicine, Drug Toxicity and Efficacy Testing, and Others), Source (Pluripotent Stem Cell and Organ Specific Adult Stem Cell), Type (Instruments, Consumables, and Services), and Geography

オルガノイド市場は、2022年の25億700万米ドルから2030年には122億600万米ドルに成長すると予想されており、2022年から2030年までの年平均成長率は21.9％と推定されている。腫瘍モデリングとバイオバンキングに対... もっと見る

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オルガノイド市場は、2022年の25億700万米ドルから2030年には122億600万米ドルに成長すると予想されており、2022年から2030年までの年平均成長率は21.9％と推定されている。腫瘍モデリングとバイオバンキングに対する需要の高まり、個別化医薬品の採用拡大、動物実験モデルの代替品開発への注目の高まりが、オルガノイド市場成長の原動力となっている。オルガノイド市場のトレンドには、オルガノイドとオルガン・オンチップの組み合わせが含まれる。

オルガノイドは、幹細胞由来の極小で自己組織化された三次元組織培養物である。このような培養物は、臓器の複雑さの多くを再現したり、特定の種類の細胞のみを作り出すなど、臓器の特定の側面を表現するように作ることができる。オルガノイドは幹細胞（無限に分裂し、子孫の一部として様々な種類の細胞を作り出すことができる細胞）から成長する。オルガノイドの大きさは、髪の毛の幅に満たないものから5ミリメートルのものまで様々である。

オルガノイド市場で事業を展開する多くの市場関係者や研究機関は、自社の製品ポートフォリオを拡大し、市場シェアを拡大するために先進技術を開発している。オルガノイドに関連する最近の動きをいくつか紹介しよう：

o 2020年11月、Cellesce Ltd.は、人体内の生理的環境を模倣し、患者由来オルガノイドの製造、スケールアップ、再現性の向上を可能にする完全合成の動物実験を伴わない三次元（3D）足場の開発について、Manchester BIOGEL社とパートナーシップを締結した。

o 2020年11月、Cellesce Ltd.は、人体内の生理的環境を模倣し、患者由来オルガノイドの製造、スケールアップ、再現性の向上を可能にする完全合成の動物実験を伴わない三次元（3D）足場の開発に関して、Manchester BIOGEL社とパートナーシップを締結した。

このように、この開発は予測期間中、オルガノイド市場に新たなトレンドをもたらす可能性が高い。

新薬や先端薬に対する需要の高まりが、創薬・研究全体のペースを押し上げている。ClinicalTrials.govによると、2020年の臨床試験総数は356,282件と推定されている。Hubrecht研究所の最近の調査によると、オルガノイドは、薬剤の恩恵を受けそうにない患者を特定することで、高価な薬剤の費用対効果を高める可能性があるとしている。世界的な臨床試験の増加は、オルガノイドモデルを含む先進医療技術の需要を促進すると予想される。

さらに、創薬におけるオルガノイドはがんだけに限らず、嚢胞性線維症、多発性嚢胞腎、小頭症、腸や気道の感染症など、他の疾患でも使用されている。例えば、オルガノイドは臓器の構造や機能など、臓器の特性を要約することができる。また、オルガノイドは組織や臓器の本来の遺伝的・エピジェネティックな状態を復元できるため、遺伝子編集に適している。様々な研究が、CRISPR-Cas9技術とオルガノイドの組み合わせによる良好な結果を示しており、嚢胞性線維症におけるブレークスルーの機会を広げている。2020年に発表された研究「CRISPR-Based Adenine Editors Correct Nonsense Mutation in a Cystic Fibrosis Organoid Biobank」によると、嚢胞性線維症腸管オルガノイドのバイオバンクは664人の患者を代表し、そのうちの〜20％がアデニン塩基エディターによって嚢胞性線維症膜貫通型伝導体受容体のナンセンス変異を理論的に効率よく修復することができた。いくつかの動物モデルで遺伝子編集オルガノイドの成果はあるものの、その効率は著しく低く、成功率は高くない。従って、遺伝子編集オルガノイドの安全性、長期安定性、機能性のためのプロセスを研究開発することが極めて重要である。

さらに、COVID-19のパンデミックは、ヒト肺オルガノイドモデルを開発する必要性を引き起こした。例えば、ミリポア・シグマ社は3dGROヒト肺オルガノイド培養システムを開発し、研究者がヒト肺上皮のオルガノイドモデルを培養するための臓器組織を管理、アクセス、再現できるようにした。

したがって、このような技術革新は、オルガノイド市場の成長にとってより大きな成長機会を提供すると期待される。

アプリケーションに基づく洞察

オルガノイド市場は用途別に、発生生物学、感染症病態学、再生医療、薬剤毒性・有効性試験、創薬・個別化医療、その他に分類される。2022年には、発生生物学が市場で最大のシェアを占め、創薬・個別化医療が予測期間中に最も高いCAGRを記録すると予測されている。

情報源に基づく洞察

オルガノイド市場は供給源に基づき、多能性幹細胞と臓器特異的成体幹細胞に二分される。多能性幹細胞セグメントは2022年に市場でより大きなシェアを占め、予測期間中により高いCAGRを記録すると予想される。

世界保健機関（WHO）、米国国勢調査局、米国国立医学図書館は、オルガノイド市場に関するレポートを作成する際に参照した主な一次および二次情報源の一部である。

タイプ別洞察

オルガノイド市場は、タイプ別に機器、消耗品、サービスに二分される。消耗品セグメントは2022年に市場で大きなシェアを占め、予測期間中により高いCAGRを記録すると予想されている。

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TABLE OF CONTENTS

1. Introduction
1.1 The Insight Partners Research Report Guidance
1.2 Market Segmentation
2. Executive Summary
2.1 Key Insights
2.2 Market Attractiveness
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. Organoids Market Landscape
4.1 Overview
4.2 PEST Analysis
4.2.1 North America PEST Analysis
4.2.2 Europe PEST Analysis
4.2.3 Asia Pacific PEST Analysis
4.2.4 South & Central America PEST Analysis
4.2.5 Middle East & Africa PEST Analysis
5. Organoids Market - Key Industry Dynamics
5.1 Key Market Drivers:
5.1.1 Increasing Demand for Tumor Modeling and Biobanking
5.1.2 Growing Adoption of Personalized Drugs
5.1.3 Rising Focus on Developing Alternatives for Animal Testing Models
5.2 Key Market Restraints:
5.2.1 Issues Related to Incorporation of Organoids into Existing Workflows
5.2.2 Dearth of Skilled Professionals
5.3 Key Market Opportunities:
5.3.1 Focus on Drug Discovery Activities
5.4 Future Trends:
5.4.1 Combining Organoid with Organ-On-A-Chip
5.5 Impact Analysis:
6. Organoids Market - Global Market Analysis
6.1 Organoids Market Revenue (US$ Mn), 2022 – 2030
7. Global Organoids Market – Revenue and Forecast to 2030 – by Organ Type
7.1 Overview
7.2 Organoids Market Revenue Share, by Organ Type 2022 & 2030 (%)
7.3 Stomach
7.3.1 Overview
7.3.2 Stomach: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.4 Intestine
7.4.1 Overview
7.4.2 Intestine: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.5 Liver
7.5.1 Overview
7.5.2 Liver: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.6 Pancreas
7.6.1 Overview
7.6.2 Pancreas: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.7 Lung
7.7.1 Overview
7.7.2 Lung: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.8 Brain
7.8.1 Overview
7.8.2 Brain: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.9 Kidney
7.9.1 Overview
7.9.2 Kidney: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
7.10 Others
7.10.1 Overview
7.10.2 Others: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8. Global Organoids Market – Revenue and Forecast to 2030 – by Application
8.1 Overview
8.2 Organoids Market Revenue Share, by Application 2022 & 2030 (%)
8.3 Developmental Biology
8.3.1 Overview
8.3.2 Developmental Biology: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8.4 Disease Pathology of Infectious Disease
8.4.1 Overview
8.4.2 Disease Pathology of Infectious Disease: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8.5 Regenerative Medicine
8.5.1 Overview
8.5.2 Regenerative Medicine: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8.6 Drug Toxicity and Efficacy Testing
8.6.1 Overview
8.6.2 Drug Toxicity and Efficacy Testing: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8.7 Drug Discovery and Personalized Medicine
8.7.1 Overview
8.7.2 Drug Discovery and Personalized Medicine: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
8.8 Others
8.8.1 Overview
8.8.2 Others: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
9. Global Organoids Market – Revenue and Forecast to 2030 – by Source
9.1 Overview
9.2 Organoids Market Revenue Share, by Source 2022 & 2030 (%)
9.3 Pluripotent Stem Cells
9.3.1 Overview
9.3.2 Pluripotent Stem Cells: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
9.4 Organ-specific Adult Stem Cells
9.4.1 Overview
9.4.2 Organ-specific Adult Stem Cells: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
10. Global Organoids Market – Revenue and Forecast to 2030 – by Type
10.1 Overview
10.2 Organoids Market Revenue Share, by Type 2022 & 2030 (%)
10.3 Instruments
10.3.1 Overview
10.3.2 Instruments: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
10.4 Consumables
10.4.1 Overview
10.4.2 Consumables: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
10.5 Services
10.5.1 Overview
10.5.2 Services: Organoids Market – Revenue and Forecast to 2030 (US$ Million)
11. Organoids Market - Geographical Analysis
11.1 North America Organoids Market, Revenue And Forecast To 2030
11.1.1 Overview
11.1.2 North America Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.1.3 North America Organoids Market, by Organ Type
11.1.4 North America Organoids Market, by Application
11.1.5 North America Organoids Market, by Source
11.1.6 North America Organoids Market, by Type
11.1.7 North America Organoids Market, by Country
11.1.7.1 US
11.1.7.1.1 Overview
11.1.7.1.2 US Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.1.7.1.3 US Organoids Market, by Organ Type
11.1.7.1.4 US Organoids Market, by Application
11.1.7.1.5 US Organoids Market, by Source
11.1.7.1.6 US Organoids Market, by Type
11.1.7.2 Canada
11.1.7.2.1 Overview
11.1.7.2.2 Canada Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.1.7.2.3 Canada Organoids Market, by Organ Type
11.1.7.2.4 Canada Organoids Market, by Application
11.1.7.2.5 Canada Organoids Market, by Source
11.1.7.2.6 Canada Organoids Market, by Type
11.1.7.3 Mexico
11.1.7.3.1 Overview
11.1.7.3.2 Mexico Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.1.7.3.3 Mexico Organoids Market, by Organ Type
11.1.7.3.4 Mexico Organoids Market, by Application
11.1.7.3.5 Mexico Organoids Market, by Source
11.1.7.3.6 Mexico Organoids Market, by Type
11.2 Europe Organoids Market, Revenue And Forecast to 2030
11.2.1 Overview
11.2.2 Europe Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.2.3 Europe Organoids Market, by Organ Type
11.2.4 Europe Organoids Market, by Application
11.2.5 Europe Organoids Market, by Source
11.2.6 Europe Organoids Market, by Type
11.2.7 Europe Organoids Market by Country
11.2.7.1 Germany
11.2.7.1.1 Overview
11.2.7.1.2 Germany Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.2.7.1.3 Germany Organoids Market, by Organ Type
11.2.7.1.4 Germany Organoids Market, by Application
11.2.7.1.5 Germany Organoids Market, by Source
11.2.7.1.6 Germany Organoids Market, by Type
11.2.7.2 UK
11.2.7.2.1 Overview
11.2.7.2.2 UK Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.2.7.2.3 UK Organoids Market, by Organ Type
11.2.7.2.4 UK Organoids Market, by Application
11.2.7.2.5 UK Organoids Market, by Source
11.2.7.2.6 UK Organoids Market, by Type
11.2.7.3 France
11.2.7.3.1 Overview
11.2.7.3.2 France Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.2.7.3.3 France Organoids Market, by Organ Type
11.2.7.3.4 France Organoids Market, by Application
11.2.7.3.5 France Organoids Market, by Source
11.2.7.3.6 France Organoids Market, by Type
11.2.7.4 Italy
11.2.7.4.1 Overview
11.2.7.4.2 Italy Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.2.7.4.3 Italy Organoids Market, by Organ Type
11.2.7.4.4 Italy Organoids Market, by Application
11.2.7.4.5 Italy Organoids Market, by Source
11.2.7.4.6 Italy Organoids Market, by Type
11.2.7.5 Spain
11.2.7.5.1 Overview
11.2.7.5.2 Spain Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.2.7.5.3 Spain Organoids Market, by Organ Type
11.2.7.5.4 Spain Organoids Market, by Application
11.2.7.5.5 Spain Organoids Market, by Source
11.2.7.5.6 Spain Organoids Market, by Type
11.2.7.6 Rest of Europe
11.2.7.6.1 Overview
11.2.7.6.2 Rest of Europe Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.2.7.6.3 Rest of Europe Organoids Market, by Organ Type
11.2.7.6.4 Rest of Europe Organoids Market, by Application
11.2.7.6.5 Rest of Europe Organoids Market, by Source
11.2.7.6.6 Rest of Europe Organoids Market, by Type
11.3 Asia Pacific Organoids Market, Revenue And Forecast to 2030
11.3.1 Overview
11.3.2 Asia Pacific Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.3.3 Asia Pacific Organoids Market, by Organ Type
11.3.4 Asia Pacific Organoids Market, by Application
11.3.5 Asia Pacific Organoids Market, by Source
11.3.6 Asia Pacific Organoids Market, by Type
11.3.7 Asia Pacific Organoids Market by Country
11.3.7.1 China
11.3.7.1.1 Overview
11.3.7.1.2 China Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.3.7.1.3 China Organoids Market, by Organ Type
11.3.7.1.4 China Organoids Market, by Application
11.3.7.1.5 China Organoids Market, by Source
11.3.7.1.6 China Organoids Market, by Type
11.3.7.2 Japan
11.3.7.2.1 Overview
11.3.7.2.2 Japan Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.3.7.2.3 Japan Organoids Market, by Organ Type
11.3.7.2.4 Japan Organoids Market, by Application
11.3.7.2.5 Japan Organoids Market, by Source
11.3.7.2.6 Japan Organoids Market, by Type
11.3.7.3 India
11.3.7.3.1 Overview
11.3.7.3.2 India Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.3.7.3.3 India Organoids Market, by Organ Type
11.3.7.3.4 India Organoids Market, by Application
11.3.7.3.5 India Organoids Market, by Source
11.3.7.3.6 India Organoids Market, by Type
11.3.7.4 Australia
11.3.7.4.1 Overview
11.3.7.4.2 Australia Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.3.7.4.3 Australia Organoids Market, by Organ Type
11.3.7.4.4 Australia Organoids Market, by Application
11.3.7.4.5 Australia Organoids Market, by Source
11.3.7.4.6 Australia Organoids Market, by Type
11.3.7.5 South Korea
11.3.7.5.1 Overview
11.3.7.5.2 South Korea Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.3.7.5.3 South Korea Organoids Market, by Organ Type
11.3.7.5.4 South Korea Organoids Market, by Application
11.3.7.5.5 South Korea Organoids Market, by Source
11.3.7.5.6 South Korea Organoids Market, by Type
11.3.7.6 Rest of Asia Pacific
11.3.7.6.1 Overview
11.3.7.6.2 Rest of Asia Pacific Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.3.7.6.3 Rest of Asia Pacific Organoids Market, by Organ Type
11.3.7.6.4 Rest of Asia Pacific Organoids Market, by Application
11.3.7.6.5 Rest of Asia Pacific Organoids Market, by Source
11.3.7.6.6 Rest of Asia Pacific Organoids Market, by Type
11.4 Middle East & Africa Organoids Market, Revenue and Forecast to 2030
11.4.1 Overview
11.4.2 Middle East & Africa Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.4.3 Middle East & Africa Organoids Market, by Organ Type
11.4.4 Middle East & Africa Organoids Market, by Application
11.4.5 Middle East & Africa Organoids Market, by Source
11.4.6 Middle East & Africa Organoids Market, by Type
11.4.7 Middle East & Africa Organoids Market by Country
11.4.7.1 Saudi Arabia
11.4.7.1.1 Overview
11.4.7.1.2 Saudi Arabia Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.4.7.1.3 Saudi Arabia Organoids Market, by Organ Type
11.4.7.1.4 Saudi Arabia Organoids Market, by Application
11.4.7.1.5 Saudi Arabia Organoids Market, by Source
11.4.7.1.6 Saudi Arabia Organoids Market, by Type
11.4.7.2 UAE
11.4.7.2.1 Overview
11.4.7.2.2 UAE Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.4.7.2.3 UAE Organoids Market, by Organ Type
11.4.7.2.4 UAE Organoids Market, by Application
11.4.7.2.5 UAE Organoids Market, by Source
11.4.7.2.6 UAE Organoids Market, by Type
11.4.7.3 South Africa
11.4.7.3.1 Overview
11.4.7.3.2 South Africa Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.4.7.3.3 South Africa Organoids Market, by Organ Type
11.4.7.3.4 South Africa Organoids Market, by Application
11.4.7.3.5 South Africa Organoids Market, by Source
11.4.7.3.6 South Africa Organoids Market, by Type
11.4.7.4 Rest of Middle East & Africa
11.4.7.4.1 Overview
11.4.7.4.2 Rest of Middle East & Africa Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.4.7.4.3 Rest of Middle East & Africa Organoids Market, by Organ Type
11.4.7.4.4 Rest of Middle East & Africa Organoids Market, by Application
11.4.7.4.5 Rest of Middle East & Africa Organoids Market, by Source
11.4.7.4.6 Rest of Middle East & Africa Organoids Market, by Type
11.5 South & Central America Organoids Market, Revenue and Forecast to 2030
11.5.1 Overview
11.5.2 South & Central America Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.5.3 South & Central America Organoids Market, by Organ Type
11.5.4 South & Central America Organoids Market, by Application
11.5.5 South & Central America Organoids Market, by Source
11.5.6 South & Central America Organoids Market, by Type
11.5.7 South & Central America Organoids Market by Country
11.5.7.1 Brazil
11.5.7.1.1 Overview
11.5.7.1.2 Brazil Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.5.7.1.3 Brazil Organoids Market, by Organ Type
11.5.7.1.4 Brazil Organoids Market, by Application
11.5.7.1.5 Brazil Organoids Market, by Source
11.5.7.1.6 Brazil Organoids Market, by Type
11.5.7.2 Argentina
11.5.7.2.1 Overview
11.5.7.2.2 Argentina Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.5.7.2.3 Argentina Organoids Market, by Organ Type
11.5.7.2.4 Argentina Organoids Market, by Application
11.5.7.2.5 Argentina Organoids Market, by Source
11.5.7.2.6 Argentina Organoids Market, by Type
11.5.7.3 Rest of South & Central America
11.5.7.3.1 Overview
11.5.7.3.2 Rest of South & Central America Organoids Market Revenue and Forecast to 2030 (US$ Mn)
11.5.7.3.3 Rest of South & Central America Organoids Market, by Organ Type
11.5.7.3.4 Rest of South & Central America Organoids Market, by Application
11.5.7.3.5 Rest of South & Central America Organoids Market, by Source
11.5.7.3.6 Rest of South & Central America Organoids Market, by Type
12. Pre & Post Covid-19 Impact
12.1 Pre & Post Covid-19 Impact
13. Organoids Market Industry Landscape
13.1 Overview
13.2 Growth Strategies Done by the Companies in the Market, (%)
13.3 Organic Developments
13.3.1 Overview
13.4 Inorganic Developments
13.4.1 Overview
14. Organoids Market, Key Company Profiles
14.1 STEMCELL Technologies Inc.
14.1.1 Key Facts
14.1.2 Business Description
14.1.3 Products and Services
14.1.4 Financial Overview
14.1.5 SWOT Analysis
14.1.6 Key Developments
14.2 Cellesce Ltd
14.2.1 Key Facts
14.2.2 Business Description
14.2.3 Products and Services
14.2.4 Financial Overview
14.2.5 SWOT Analysis
14.2.6 Key Developments
14.3 Hubrecht Organoid Technology
14.3.1 Key Facts
14.3.2 Business Description
14.3.3 Products and Services
14.3.4 Financial Overview
14.3.5 SWOT Analysis
14.3.6 Key Developments
14.4 Definigen
14.4.1 Key Facts
14.4.2 Business Description
14.4.3 Products and Services
14.4.4 Financial Overview
14.4.5 SWOT Analysis
14.4.6 Key Developments
14.5 Organoid Therapeutics
14.5.1 Key Facts
14.5.2 Business Description
14.5.3 Products and Services
14.5.4 Financial Overview
14.5.5 SWOT Analysis
14.5.6 Key Developments
14.6 3Dnamics Inc.
14.6.1 Key Facts
14.6.2 Business Description
14.6.3 Products and Services
14.6.4 Financial Overview
14.6.5 SWOT Analysis
14.6.6 Key Developments
14.7 Thermo Fisher Scientific Inc
14.7.1 Key Facts
14.7.2 Business Description
14.7.3 Products and Services
14.7.4 Financial Overview
14.7.5 SWOT Analysis
14.7.6 Key Developments
14.8 Corning Inc
14.8.1 Key Facts
14.8.2 Business Description
14.8.3 Products and Services
14.8.4 Financial Overview
14.8.5 SWOT Analysis
14.8.6 Key Developments
14.9 Merck KGaA
14.9.1 Key Facts
14.9.2 Business Description
14.9.3 Products and Services
14.9.4 Financial Overview
14.9.5 SWOT Analysis
14.9.6 Key Developments
14.10 InSphero
14.10.1 Key Facts
14.10.2 Business Description
14.10.3 Products and Services
14.10.4 Financial Overview
14.10.5 SWOT Analysis
14.10.6 Key Developments
15. Appendix
15.1 About Us
15.2 Glossary of Terms

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Table of Contents

Summary

The organoids market is expected to grow from US$ 2.507 billion in 2022 to US$ 12.206 billion by 2030; it is estimated to register a CAGR of 21.9% from 2022 to 2030. The higher demand for tumor modeling and biobanking, growing adoption of personalized drugs, and rising focus on developing alternatives for animal testing models drive the organoids market growth. The organoids market trends include combining organoids with organ-on-a-chip.

The organoids are tiny, self-organized, three-dimensional tissue cultures that are derived from stem cells. Such cultures can be crafted to replicate much of the complexity of an organ or to express selected aspects of it, like producing only certain types of cells. Organoids grow from stem cells—cells that can divide indefinitely and produce different types of cells as part of their progeny. Organoids can range in size from less than the width of a hair to five millimeters.

Many market players and research institutes operating in the organoids market are developing advanced technologies to expand their product portfolios and increase their market shares. A few of the recent developments related to organoids are mentioned below:

o In November 2020, Cellesce Ltd. entered a partnership with Manchester BIOGEL for the development of fully synthetic animal-free three-dimensional (3D) scaffolds that mimic the physiological environment in the human body and enable the manufacture, scale up, and improved reproducibility of patient-derived organoids.

o In November 2020, Cellesce Ltd. entered a partnership with Manchester BIOGEL for the development of fully synthetic animal-free three-dimensional (3D) scaffolds that mimic the physiological environment in the human body and enable the manufacture, scale up, and improved reproducibility of patient-derived organoids.

Thus, the development is likely to introduce new trends in the organoids market during the forecast period.

The increasing demand for new and advanced drugs is driving the overall pace of drug discovery and research. According to ClinicalTrials.gov, the total number of clinical trial studies in 2020 was estimated to be 356,282. A recent survey by the Hubrecht Institute states that organoids can potentially make expensive drugs more cost-effective by identifying patients who are not likely to benefit from the drug. An increasing number of clinical trials worldwide is expected to drive the demand for advanced medical technologies, including organoid models.

Further, organoids in drug discovery are not limited to just cancer, they are also used in other diseases, such as cystic fibrosis, polycystic kidney disease, microcephaly, and infectious diseases of the gut and airway. For instance, organoids can summarize the properties of an organ, such as organ structure and function. Also, organoids can restore a tissue or organ's original genetic and epigenetic state, making them suitable for gene editing. Various studies have shown positive results of combining CRISPR-Cas9 technology with organoids, which has expanded opportunities for breakthroughs in cystic fibrosis. According to a study ‘CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank,’ published in 2020, a biobank of cystic fibrosis intestinal organoids represented 664 patients, and ~20% of them were theoretically able to efficiently repair nonsense mutations in the cystic fibrosis transmembrane conductor receptor through adenine base editors. Despite a few achievements of gene-edited organoids in some animal models, their efficiency is significantly low, and the success rate is not high. Therefore, it is crucial to research and develop a process for gene-edited organoids' safety, long-term stability, and functionality.

Moreover, the COVID-19 pandemic triggered the need to develop human lung organoid models. For instance, MilliporeSigma developed a 3dGRO Human Lung Organoid Culture System that allows researchers to control, access, and reproduce organ tissue for culturing an organoid model of human lung epithelium that can aid in obtaining positive and successful results during their research.

Thus, such innovations are expected to offer more significant growth opportunities for organoids market growth.

Application-Based Insights

Based on application, the organoids market is divided into developmental biology, disease pathology of infectious disease, regenerative medicine, drug toxicity and efficacy testing, drug discovery and personalized medicine, and others. In 2022, the developmental biology held the largest share of the market and drug discovery & personalized medicine is anticipated to register the highest CAGR during the forecast period.

Source-Based Insights

Based on source, the organoids market is bifurcated into pluripotent stem cells and organ-specific adult stem cells. The pluripotent stem cells segment held a larger share of the market in 2022 and is expected to record at a higher CAGR during the forecast period.

The World Health Organization (WHO), the US Census Bureau, and the US National Library of Medicine are a few of the major primary and secondary sources referred to while preparing the report on the organoids market.

Type-Based Insights

Based on type, the organoids market is bifurcated into instruments, consumables, and services. The consumables segment held a larger share of the market in 2022 and is expected to record at a higher CAGR during the forecast period.

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目次

Summary

Table of Contents

ご注文は、お電話またはWEBから承ります。お見積もりの作成もお気軽にご相談ください。

本レポートと同分野（その他）の最新刊レポート

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