Summary

The 7 major synovial sarcoma markets reached a value of US$ 75.3 Million in 2023. Looking forward, IMARC Group expects the 7MM to reach US$ 114.0 Million by 2034, exhibiting a growth rate (CAGR) of 3.84% during 2024-2034.

The synovial sarcoma market has been comprehensively analyzed in IMARC's new report titled "Synovial Sarcoma Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034". Synovial sarcoma refers to a type of soft tissue sarcoma, which is a cancer that develops in the body's connective tissues, such as muscles, fat, blood vessels, etc. The most common locations are near joints and tendons in the arms or legs, but it can also occur in other parts of the body, including the chest and abdomen. In many cases, synovial sarcoma may not cause any noticeable symptoms in its early stages. As the tumor becomes larger, a painless lump or swelling can develop in the affected area, which may gradually increase in size over time. In some cases, the ailment may cause pain, numbness, or weakness if it presses on nearby nerves or blood vessels. Various other symptoms include stiffness, limited range of motion in joints, unexplained weight loss, etc. Diagnosing synovial sarcoma usually involves a combination of medical imaging procedures and a biopsy of the suspicious area. Several imaging tests, such as X-rays, MRIs, CT scans, ultrasounds, etc., help in identifying the location, size, and characteristics of the tumor. Additionally, a biopsy can confirm the diagnosis and provide information on the grade as well as the stage of cancer.

The increasing cases of genetic mutations that affect genes involved in cell growth, differentiation, and apoptosis, are primarily driving the synovial sarcoma market. Besides this, the widespread adoption of immune checkpoint inhibitors, such as pembrolizumab and nivolumab, which block proteins that inhibit the immune system's ability to recognize and attack cancer cells, is also propelling the market growth. Furthermore, the escalating utilization of radiofrequency ablation, a minimally invasive procedure that utilizes heat to destroy cancer cells for treating synovial sarcoma confined to a single location, is acting as another significant growth-inducing factor. Additionally, numerous key players are investing in R&D activities to introduce targeted drugs and therapies that target specific molecules or pathways involved in the formation and growth of cancer cells. This, in turn, is also creating a positive outlook for the market. Moreover, the ongoing advancements in MRI technology, such as the launch of diffusion-weighted imaging (DWI) and dynamic contrast-enhanced MRI (DCE-MRI), which provide better visualization of tumor margins, invasion of adjacent structures, and detection of distant metastasis, are expected to drive the synovial sarcoma market in the coming years.

IMARC Group's new report provides an exhaustive analysis of the synovial sarcoma market in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. The report also provides the current and future patient pool across the seven major markets. According to the report the United States has the largest patient pool for synovial sarcoma and also represents the largest market for its treatment. Furthermore, the current treatment practice/algorithm, market drivers, challenges, opportunities, reimbursement scenario and unmet medical needs, etc. have also been provided in the report. This report is a must-read for manufacturers, investors, business strategists, researchers, consultants, and all those who have any kind of stake or are planning to foray into the synovial sarcoma market in any manner.

Time Period of the Study

Base Year: 2023
Historical Period: 2018-2023
Market Forecast: 2024-2034

Countries Covered

United States
Germany
France
United Kingdom
Italy
Spain
Japan

Analysis Covered Across Each Country

Historical, current, and future epidemiology scenario
Historical, current, and future performance of the synovial sarcoma market
Historical, current, and future performance of various therapeutic categories in the market
Sales of various drugs across the synovial sarcoma market
Reimbursement scenario in the market
In-market and pipeline drugs
Competitive Landscape:
This report also provides a detailed analysis of the current synovial sarcoma marketed drugs and late-stage pipeline drugs.

In-Market Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

Late-Stage Pipeline Drugs

Drug Overview
Mechanism of Action
Regulatory Status
Clinical Trial Results
Drug Uptake and Market Performance

*Kindly note that the drugs in the above table only represent a partial list of marketed/pipeline drugs, and the complete list has been provided in the report.

Key Questions Answered in this Report:
Market Insights

How has the synovial sarcoma market performed so far and how will it perform in the coming years?
What are the markets shares of various therapeutic segments in 2023 and how are they expected to perform till 2034?
What was the country-wise size of the synovial sarcoma market across the seven major markets in 2023 and what will it look like in 2034?
What is the growth rate of the synovial sarcoma market across the seven major markets and what will be the expected growth over the next ten years?
What are the key unmet needs in the market?

Epidemiology Insights

What is the number of prevalent cases (2018-2034) of synovial sarcoma across the seven major markets?
What is the number of prevalent cases (2018-2034) of synovial sarcoma by age across the seven major markets?
What is the number of prevalent cases (2018-2034) of synovial sarcoma by gender across the seven major markets?
How many patients are diagnosed (2018-2034) with synovial sarcoma across the seven major markets?
What is the size of the synovial sarcoma patient pool (2018-2023) across the seven major markets?
What would be the forecasted patient pool (2024-2034) across the seven major markets?
What are the key factors driving the epidemiological trend of synovial sarcoma?
What will be the growth rate of patients across the seven major markets?

Synovial Sarcoma: Current Treatment Scenario, Marketed Drugs and Emerging Therapies

What are the current marketed drugs and what are their market performance?
What are the key pipeline drugs and how are they expected to perform in the coming years?
How safe are the current marketed drugs and what are their efficacies?
How safe are the late-stage pipeline drugs and what are their efficacies?
What are the current treatment guidelines for synovial sarcoma drugs across the seven major markets?
Who are the key companies in the market and what are their market shares?
What are the key mergers and acquisitions, licensing activities, collaborations, etc. related to the synovial sarcoma market?
What are the key regulatory events related to the synovial sarcoma market?
What is the structure of clinical trial landscape by status related to the synovial sarcoma market?
What is the structure of clinical trial landscape by phase related to the synovial sarcoma market?
What is the structure of clinical trial landscape by route of administration related to the synovial sarcoma market?

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Table of Contents

1 Preface

2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology

3 Executive Summary

4 Synovial Sarcoma - Introduction
4.1 Overview
4.2 Regulatory Process
4.3 Epidemiology (2018-2023) and Forecast (2024-2034)
4.4 Market Overview (2018-2023) and Forecast (2024-2034)
4.5 Competitive Intelligence

5 Synovial Sarcoma - Disease Overview
5.1 Introduction
5.2 Symptoms and Diagnosis
5.3 Pathophysiology
5.4 Causes and Risk Factors
5.5 Treatment

6 Patient Journey

7 Synovial Sarcoma - Epidemiology and Patient Population
7.1 Epidemiology - Key Insights
7.2 Epidemiology Scenario - Top 7 Markets
7.2.1 Epidemiology Scenario (2018-2023)
7.2.2 Epidemiology Forecast (2024-2034)
7.2.3 Epidemiology by Age (2018-2034)
7.2.4 Epidemiology by Gender (2018-2034)
7.2.5 Diagnosed Cases (2018-2034)
7.2.6 Patient Pool/Treated Cases (2018-2034)
7.3 Epidemiology Scenario - United States
7.3.1 Epidemiology Scenario (2018-2023)
7.3.2 Epidemiology Forecast (2024-2034)
7.3.3 Epidemiology by Age (2018-2034)
7.3.4 Epidemiology by Gender (2018-2034)
7.3.5 Diagnosed Cases (2018-2034)
7.3.6 Patient Pool/Treated Cases (2018-2034)
7.4 Epidemiology Scenario - Germany
7.4.1 Epidemiology Scenario (2018-2023)
7.4.2 Epidemiology Forecast (2024-2034)
7.4.3 Epidemiology by Age (2018-2034)
7.4.4 Epidemiology by Gender (2018-2034)
7.4.5 Diagnosed Cases (2018-2034)
7.4.6 Patient Pool/Treated Cases (2018-2034)
7.5 Epidemiology Scenario - France
7.5.1 Epidemiology Scenario (2018-2023)
7.5.2 Epidemiology Forecast (2024-2034)
7.5.3 Epidemiology by Age (2018-2034)
7.5.4 Epidemiology by Gender (2018-2034)
7.5.5 Diagnosed Cases (2018-2034)
7.5.6 Patient Pool/Treated Cases (2018-2034)
7.6 Epidemiology Scenario - United Kingdom
7.6.1 Epidemiology Scenario (2018-2023)
7.6.2 Epidemiology Forecast (2024-2034)
7.6.3 Epidemiology by Age (2018-2034)
7.6.4 Epidemiology by Gender (2018-2034)
7.6.5 Diagnosed Cases (2018-2034)
7.6.6 Patient Pool/Treated Cases (2018-2034)
7.7 Epidemiology Scenario - Italy
7.7.1 Epidemiology Scenario (2018-2023)
7.7.2 Epidemiology Forecast (2024-2034)
7.7.3 Epidemiology by Age (2018-2034)
7.7.4 Epidemiology by Gender (2018-2034)
7.7.5 Diagnosed Cases (2018-2034)
7.7.6 Patient Pool/Treated Cases (2018-2034)
7.8 Epidemiology Scenario - Spain
7.8.1 Epidemiology Scenario (2018-2023)
7.8.2 Epidemiology Forecast (2024-2034)
7.8.3 Epidemiology by Age (2018-2034)
7.8.4 Epidemiology by Gender (2018-2034)
7.8.5 Diagnosed Cases (2018-2034)
7.8.6 Patient Pool/Treated Cases (2018-2034)
7.9 Epidemiology Scenario - Japan
7.9.1 Epidemiology Scenario (2018-2023)
7.9.2 Epidemiology Forecast (2024-2034)
7.9.3 Epidemiology by Age (2018-2034)
7.9.4 Epidemiology by Gender (2018-2034)
7.9.5 Diagnosed Cases (2018-2034)
7.9.6 Patient Pool/Treated Cases (2018-2034)

8 Synovial Sarcoma - Treatment Algorithm, Guidelines, and Medical Practices
8.1 Guidelines, Management and Treatment
8.2 Treatment Algorithm

9 Synovial Sarcoma - Unmet Needs

10 Synovial Sarcoma - Key Endpoints of Treatment

11 Synovial Sarcoma - Marketed Products
11.1 List of Synovial Sarcoma Marketed Drugs Across the Top 7 Markets
11.1.1 lartruvo (Olaratumab) - Eli Lilly and Company
11.1.1.1 Drug Overview
11.1.1.2 Mechanism of Action
11.1.1.3 Regulatory Status
11.1.1.4 Clinical Trial Results
11.1.1.5 Sales Across Major Markets

Kindly note that the above only represents a partial list of marketed drugs, and the complete list has been provided in the report.

12 Synovial Sarcoma - Pipeline Drugs
12.1 List of Synovial Sarcoma Pipeline Drugs Across the Top 7 Markets
12.1.1 TBI-1301 - Takara Bio
12.1.1.1 Drug Overview
12.1.1.2 Mechanism of Action
12.1.1.3 Clinical Trial Results
12.1.1.4 Safety and Efficacy
12.1.1.5 Regulatory Status
12.1.2 FHD-609 - Foghorn Therapeutics
12.1.2.1 Drug Overview
12.1.2.2 Mechanism of Action
12.1.2.3 Clinical Trial Results
12.1.2.4 Safety and Efficacy
12.1.2.5 Regulatory Status
12.1.3 OTSA101-DTPA-111In - OncoTherapy Science
12.1.3.1 Drug Overview
12.1.3.2 Mechanism of Action
12.1.3.3 Clinical Trial Results
12.1.3.4 Safety and Efficacy
12.1.3.5 Regulatory Status
12.1.4 CFT8634 - C4 Therapeutics
12.1.4.1 Drug Overview
12.1.4.2 Mechanism of Action
12.1.4.3 Clinical Trial Results
12.1.4.4 Safety and Efficacy
12.1.4.5 Regulatory Status
12.1.5 Afamitresgene autoleucel - Adaptimmune
12.1.5.1 Drug Overview
12.1.5.2 Mechanism of Action
12.1.5.3 Clinical Trial Results
12.1.5.4 Safety and Efficacy
12.1.5.5 Regulatory Status

Kindly note that the above only represents a partial list of pipeline drugs, and the complete list has been provided in the report.

13. Synovial Sarcoma - Attribute Analysis of Key Marketed and Pipeline Drugs

14. Synovial Sarcoma – Clinical Trial Landscape
14.1 Drugs by Status
14.2 Drugs by Phase
14.3 Drugs by Route of Administration
14.4 Key Regulatory Events

15 Synovial Sarcoma - Market Scenario
15.1 Market Scenario - Key Insights
15.2 Market Scenario - Top 7 Markets
15.2.1 Synovial Sarcoma - Market Size
15.2.1.1 Market Size (2018-2023)
15.2.1.2 Market Forecast (2024-2034)
15.2.2 Synovial Sarcoma - Market Size by Therapies
15.2.2.1 Market Size by Therapies (2018-2023)
15.2.2.2 Market Forecast by Therapies (2024-2034)
15.3 Market Scenario - United States
15.3.1 Synovial Sarcoma - Market Size
15.3.1.1 Market Size (2018-2023)
15.3.1.2 Market Forecast (2024-2034)
15.3.2 Synovial Sarcoma - Market Size by Therapies
15.3.2.1 Market Size by Therapies (2018-2023)
15.3.2.2 Market Forecast by Therapies (2024-2034)
15.3.3 Synovial Sarcoma - Access and Reimbursement Overview
15.4 Market Scenario - Germany
15.4.1 Synovial Sarcoma - Market Size
15.4.1.1 Market Size (2018-2023)
15.4.1.2 Market Forecast (2024-2034)
15.4.2 Synovial Sarcoma - Market Size by Therapies
15.4.2.1 Market Size by Therapies (2018-2023)
15.4.2.2 Market Forecast by Therapies (2024-2034)
15.4.3 Synovial Sarcoma - Access and Reimbursement Overview
15.5 Market Scenario - France
15.5.1 Synovial Sarcoma - Market Size
15.5.1.1 Market Size (2018-2023)
15.5.1.2 Market Forecast (2024-2034)
15.5.2 Synovial Sarcoma - Market Size by Therapies
15.5.2.1 Market Size by Therapies (2018-2023)
15.5.2.2 Market Forecast by Therapies (2024-2034)
15.5.3 Synovial Sarcoma - Access and Reimbursement Overview
15.6 Market Scenario - United Kingdom
15.6.1 Synovial Sarcoma - Market Size
15.6.1.1 Market Size (2018-2023)
15.6.1.2 Market Forecast (2024-2034)
15.6.2 Synovial Sarcoma - Market Size by Therapies
15.6.2.1 Market Size by Therapies (2018-2023)
15.6.2.2 Market Forecast by Therapies (2024-2034)
15.6.3 Synovial Sarcoma - Access and Reimbursement Overview
15.7 Market Scenario - Italy
15.7.1 Synovial Sarcoma - Market Size
15.7.1.1 Market Size (2018-2023)
15.7.1.2 Market Forecast (2024-2034)
15.7.2 Synovial Sarcoma - Market Size by Therapies
15.7.2.1 Market Size by Therapies (2018-2023)
15.7.2.2 Market Forecast by Therapies (2024-2034)
15.7.3 Synovial Sarcoma - Access and Reimbursement Overview
15.8 Market Scenario - Spain
15.8.1 Synovial Sarcoma - Market Size
15.8.1.1 Market Size (2018-2023)
15.8.1.2 Market Forecast (2024-2034)
15.8.2 Synovial Sarcoma - Market Size by Therapies
15.8.2.1 Market Size by Therapies (2018-2023)
15.8.2.2 Market Forecast by Therapies (2024-2034)
15.8.3 Synovial Sarcoma - Access and Reimbursement Overview
15.9 Market Scenario - Japan
15.9.1 Synovial Sarcoma - Market Size
15.9.1.1 Market Size (2018-2023)
15.9.1.2 Market Forecast (2024-2034)
15.9.2 Synovial Sarcoma - Market Size by Therapies
15.9.2.1 Market Size by Therapies (2018-2023)
15.9.2.2 Market Forecast by Therapies (2024-2034)
15.9.3 Synovial Sarcoma - Access and Reimbursement Overview

16 Synovial Sarcoma - Recent Events and Inputs From Key Opinion Leaders

17 Synovial Sarcoma Market - SWOT Analysis
17.1 Strengths
17.2 Weaknesses
17.3 Opportunities
17.4 Threats

18 Synovial Sarcoma Market – Strategic Recommendations

19 Appendix