Summary
Japan Inflammatory Bowel Disease (IBD) Drugs Market was valued at USD 401.02 Million in 2024 and is expected to reach USD 516.04 Million by 2030 with a CAGR of 4.25% during the forecast period. The Japan Inflammatory Bowel Disease (IBD) drugs market is driven by several factors, including the rising incidence of IBD conditions like Crohn's disease and ulcerative colitis, which increases demand for effective treatments. Advances in pharmaceutical research have led to the development of innovative biologics and targeted therapies, offering improved efficacy and safety profiles. Growing awareness and diagnosis of IBD contribute to earlier treatment initiation and better management. Supportive government policies and increased healthcare expenditure for chronic diseases fuel market growth. The expansion of healthcare infrastructure and the presence of a well-established medical community further drive the adoption of advanced IBD therapies in Japan.
Key Market Drivers
Growing Awareness and Improved Diagnosis
Increasing awareness and improved diagnostic capabilities are pivotal drivers of the expansion of the Japan Inflammatory Bowel Disease (IBD) Drugs Market. As awareness of IBD grows among both healthcare professionals and the general public, there is a marked shift towards emphasizing early diagnosis and timely intervention. This heightened awareness is largely attributed to ongoing educational campaigns and initiatives led by healthcare organizations, patient advocacy groups, and pharmaceutical companies. Such efforts aim to educate the public about the symptoms and impacts of IBD, which include Crohn's disease and ulcerative colitis, thereby encouraging individuals to seek medical evaluation and care at earlier stages.
Advancements in diagnostic technologies have also significantly impacted the market. Modern diagnostic tools, such as high-definition endoscopy, capsule endoscopy, and advanced imaging techniques like MRI and CT scans, have greatly improved the accuracy and speed of diagnosing IBD. These technologies enable healthcare providers to visualize the gastrointestinal tract with greater detail, allowing for more precise identification of inflammation, ulceration, and other pathological changes associated with IBD. Enhanced diagnostic accuracy not only facilitates earlier detection but also helps in differentiating between IBD and other gastrointestinal disorders, leading to more effective and targeted treatment strategies. In March 2022, Galapagos NV announced that Gilead Sciences K.K., Eisai Co., Ltd. (Tokyo, Japan), and EA Pharma Co., Ltd. (Tokyo, Japan) have received approval from the Japanese Ministry of Health, Labour and Welfare (MHLW) for a second indication of Jyseleca (filgotinib). This once-daily oral JAK1 preferential inhibitor is now approved for treating patients with moderate-to-severe active ulcerative colitis (UC). This approval for Jyseleca's second indication in Japan follows data from the randomized, double-blind, placebo-controlled phase 2b/3 SELECTION study. The trial assessed Jyseleca’s efficacy and safety for inducing and maintaining remission in patients with moderately to severely active UC who had not adequately responded to, lost response to, or were intolerant of conventional or biologic therapies.
Early diagnosis is crucial for the management of IBD as it allows for the prompt initiation of therapy, which can significantly improve patient outcomes. Patients diagnosed at an early stage are more likely to benefit from treatment regimens designed to induce and maintain remission, ultimately reducing the risk of complications and improving quality of life. The availability of advanced therapies, including biologics and novel small molecules, further supports the demand for early and accurate diagnosis. These treatments, which often target specific inflammatory pathways or immune responses, are most effective when administered early in the disease course.
Expanding Healthcare Infrastructure
The expansion of healthcare infrastructure in Japan is a critical factor driving the growth of the Inflammatory Bowel Disease (IBD) drugs market. As Japan continues to enhance its healthcare system, the establishment of new hospitals, clinics, and specialized centers plays a pivotal role in improving the management and treatment of IBD. This expansion is not merely about increasing the number of healthcare facilities but also about upgrading them with the latest diagnostic and therapeutic technologies.
Newly established hospitals and clinics equipped with advanced diagnostic tools, such as high-resolution endoscopes, capsule endoscopes, and state-of-the-art imaging systems, significantly contribute to the early and accurate diagnosis of IBD. These facilities allow for more precise detection of inflammatory changes, ulcerations, and other disease manifestations, which is essential for initiating appropriate treatment strategies. Enhanced diagnostic capabilities ensure that patients receive timely and effective care, thereby driving demand for IBD drugs as clinicians are better equipped to identify and manage the condition.
The growth of specialized centers dedicated to gastrointestinal diseases, including IBD, marks a significant development in the healthcare infrastructure. These centers are equipped with specialized equipment and staffed by experts in gastrointestinal disorders, providing comprehensive care that encompasses both diagnosis and treatment. The focus on IBD within these centers allows for the development and implementation of innovative treatment approaches, including advanced biologics and novel therapies. Such specialized care centers also foster research and clinical trials, contributing to the continuous evolution of treatment options available in the market. The expansion of healthcare infrastructure also enhances the distribution and accessibility of IBD drugs across various regions. With more healthcare facilities, patients in both urban and rural areas have improved access to medical care and pharmaceutical treatments. This widespread distribution ensures that patients receive the latest IBD therapies regardless of their geographic location, promoting equity in healthcare access. As more facilities integrate IBD management into their services, the demand for a diverse range of IBD drugs increases, driving market growth.
Rising Healthcare Expenditure
Increasing healthcare expenditure in Japan is a pivotal factor driving the growth of the Inflammatory Bowel Disease (IBD) drugs market. As Japan's healthcare spending rises, there is a significant boost in investment across various segments of the healthcare system, including advanced drug therapies for chronic conditions like IBD. This growing financial commitment directly supports the development, availability, and accessibility of cutting-edge IBD medications, including biologics and targeted therapies.
The rise in healthcare expenditure facilitates the advancement of medical technologies and pharmaceuticals, allowing for more robust research and development efforts. Pharmaceutical companies can invest more in the discovery and development of innovative drugs, leading to the introduction of new treatment options for IBD. This includes the development of biologics, which are complex drugs derived from living organisms, and targeted therapies designed to address specific pathways involved in the disease process. Increased healthcare funding supports clinical trials, regulatory approvals, and the commercialization of these advanced treatments, enhancing the overall therapeutic landscape for IBD patients.
With higher healthcare expenditure, there is also a greater focus on improving healthcare infrastructure and services. This includes investments in modern healthcare facilities, state-of-the-art diagnostic tools, and advanced treatment options. Enhanced healthcare infrastructure supports the effective diagnosis and management of IBD, leading to an increased demand for specialized drug therapies. As new treatments become available and accessible, patients benefit from more effective options, which drives further growth in the market.
Patient Demand for Personalized Treatments
The growing demand for personalized treatments in the management of Inflammatory Bowel Disease (IBD) is significantly driving the market for IBD drugs in Japan. Personalized medicine, also known as precision medicine, is an innovative approach that involves customizing treatment plans based on individual patient profiles. This personalization takes into account a range of factors, including genetic makeup, environmental influences, and lifestyle choices, to provide more effective and targeted therapies.
In the context of IBD, personalized medicine offers a substantial advantage by addressing the unique characteristics of each patient's condition. IBD encompasses chronic inflammatory disorders such as Crohn’s disease and ulcerative colitis, which can vary widely in their manifestations and progression from one patient to another. Traditional treatment approaches often employ a one-size-fits-all strategy, which may not be equally effective for every patient and could lead to varying degrees of success and potential side effects. Personalized medicine, however, tailors treatments to the individual’s specific disease profile, thereby enhancing the efficacy of the therapy and reducing the risk of adverse effects.
The shift towards personalized treatments in IBD management is driven by advancements in several key areas. Genetic research has identified various genetic markers associated with IBD, which can influence disease susceptibility, progression, and response to treatment. By analyzing these genetic factors, healthcare providers can better predict which treatments are most likely to be effective for a particular patient. This approach allows for more precise and informed decision-making, leading to improved treatment outcomes. Personalized medicine takes into account environmental and lifestyle factors that may impact IBD. For instance, dietary habits, stress levels, and exposure to environmental triggers can influence the course of the disease. By incorporating these factors into the treatment plan, physicians can offer more holistic and individualized care. This integration of multiple factors into treatment planning aligns with the growing trend of patient-centered care, where the focus is on addressing the individual’s specific needs and preferences.
Key Market Challenges
High Cost of Innovative Treatments
One of the primary challenges in the Japan Inflammatory Bowel Disease (IBD) drugs market is the high cost associated with innovative treatments. Biologics and targeted therapies, which represent the cutting-edge of IBD treatment, often come with significant price tags. These drugs, including monoclonal antibodies and JAK inhibitors, require complex manufacturing processes and extensive clinical testing, contributing to their elevated costs. While these advanced therapies offer substantial benefits in terms of efficacy and safety, the financial burden on patients and healthcare systems can be considerable. In Japan, where healthcare expenditures are meticulously managed and insurance coverage is comprehensive but often limited, the high cost of these drugs poses a significant barrier to access. Patients may face out-of-pocket expenses or require extensive insurance approvals, which can delay treatment initiation and affect adherence. The high cost of IBD drugs can strain public and private healthcare budgets, leading to increased scrutiny and potential restrictions on drug reimbursement. This financial challenge impacts both the market dynamics and patient outcomes, as effective treatments may not be accessible to all who need them.
Variability in Drug Response and Efficacy
Another significant challenge in the Japan Inflammatory Bowel Disease (IBD) drugs market is the variability in drug response and efficacy among patients. IBD is a complex and heterogeneous condition, and treatments that work well for some patients may be less effective for others. The variability in drug response is influenced by factors such as genetic differences, disease severity, and patient-specific characteristics. This unpredictability complicates treatment planning and necessitates a trial-and-error approach to find the most effective therapy for each individual. Such variability can lead to prolonged periods of ineffective treatment, increased healthcare costs, and potential adverse effects from suboptimal drug choices. The need for personalized treatment plans and frequent monitoring can put a strain on healthcare resources and may not always result in improved outcomes. Addressing this challenge requires ongoing research into biomarkers and genetic factors that can predict treatment response, as well as the development of more personalized and targeted therapeutic approaches.
Regulatory and Approval Delays
Regulatory and approval delays represent a significant challenge in the Japan Inflammatory Bowel Disease (IBD) drugs market. The process for obtaining regulatory approval for new drugs in Japan is rigorous and can be time-consuming. Pharmaceutical companies must navigate complex regulatory requirements set forth by the Pharmaceuticals and Medical Devices Agency (PMDA), which include extensive clinical trials, documentation, and evaluations. Delays in the approval process can hinder the timely availability of new and potentially life-changing treatments for patients. Such delays can affect the competitive positioning of pharmaceutical companies and impact patient access to the latest therapies. Regulatory hurdles may increase the cost of bringing new drugs to market, which can be particularly challenging for innovative therapies with high development costs. Streamlining the approval process and enhancing collaboration between regulatory bodies and pharmaceutical companies are essential to mitigating these delays and ensuring timely access to new treatments.
Key Market Trends
Increasing Incidence and Prevalence of IBD
The rising incidence and prevalence of inflammatory bowel disease (IBD) in Japan is a major factor driving the demand for IBD drugs. IBD, which includes Crohn's disease and ulcerative colitis, has seen a noticeable increase in cases across Japan. This surge can be attributed to a complex interplay of genetic, environmental, and lifestyle factors that contribute to the development and progression of the disease. In May 2022, EA Pharma Co., Ltd. and Kissei Pharmaceutical Co., Ltd. announced the launch of CAROGRA® Tablets (nonproprietary name: carotegrast methyl; “CAROGRA”) for the treatment of ulcerative colitis in Japan. The drug was added to the National Health Insurance Drug Price List on May 25. CAROGRA is a novel small molecule developed by EA Pharma (formerly Ajinomoto Pharmaceuticals Co., Ltd.), and is the world's first α4 integrin antagonist available in an oral dosage form. It targets both α4β1 and α4β7 integrins on inflammatory cells, providing anti-inflammatory effects by reducing the excessive aggregation and infiltration of these cells into the inflamed colonic mucosa in ulcerative colitis.
Genetic predisposition plays a significant role in the increasing prevalence of IBD. Research has identified various genetic markers associated with an elevated risk of developing IBD. As our understanding of these genetic factors grows, it becomes evident that a significant portion of the Japanese population may be genetically predisposed to IBD, contributing to the rising incidence. The interplay between these genetic factors and environmental triggers further exacerbates the situation, leading to a higher number of diagnosed cases.
Environmental factors, such as changes in diet, pollution, and lifestyle, also contribute to the growing prevalence of IBD. In Japan, dietary changes and urbanization have led to lifestyle shifts that are believed to impact gut health. For instance, increased consumption of processed foods and changes in traditional eating habits may influence gut microbiota, potentially contributing to the development of IBD. Environmental pollutants and exposure to various chemicals can affect gut inflammation and immune responses, further driving the incidence of IBD. Lifestyle changes, including stress and sedentary behavior, have been linked to a higher risk of developing IBD. In modern Japan, increasing stress levels and changes in physical activity patterns are believed to impact gastrointestinal health. Stress has been shown to affect gut permeability and immune function, potentially contributing to the onset and progression of IBD. As lifestyle factors evolve, their impact on IBD prevalence becomes more pronounced, necessitating effective treatment options.
Advances in Drug Development and Innovation
The Japan Inflammatory Bowel Disease (IBD) drugs market is significantly driven by advancements in drug development and innovation. The introduction of novel biologics and targeted therapies has revolutionized the treatment landscape for IBD. These advancements include the development of monoclonal antibodies, Janus kinase (JAK) inhibitors, and other advanced therapies that offer targeted action against specific inflammatory pathways involved in IBD. Innovations such as biosimilars also contribute to market growth by providing cost-effective alternatives to branded biologics. The continuous evolution in drug development, including improved efficacy and safety profiles, drives physician adoption and patient preference, expanding the market for IBD drugs. Research and development activities focused on addressing unmet needs and improving patient outcomes further stimulate market dynamics.
Segmental Insights
Disease Type Insights
Based on the Disease Type, ulcerative colitis (UC) currently dominates over Crohn’s disease. This dominance is driven by several factors related to the epidemiology, clinical management, and treatment needs specific to UC.
Ulcerative colitis, characterized by inflammation confined to the colon and rectum, is more prevalent in Japan compared to Crohn’s disease, which can affect any part of the gastrointestinal tract. The higher prevalence of UC in Japan is reflected in the greater demand for drugs targeting this condition. Epidemiological data indicates that UC cases outnumber those of Crohn’s disease, making it a focal point for pharmaceutical companies and healthcare providers. This prevalence drives the market for UC-specific therapies, which are tailored to manage the unique challenges of this condition. The clinical management of ulcerative colitis in Japan requires a range of drug therapies, from anti-inflammatory agents to biologics and immunosuppressants. UC’s treatment landscape includes established drugs such as 5-aminosalicylic acids (5-ASAs), corticosteroids, and immunomodulators, as well as newer biologic therapies. The need for ongoing management and new therapeutic options for UC patients contributes to its dominance in the market. Given the chronic nature of UC, patients often require long-term medication regimens, which drives consistent demand for these drugs.
Drug Class Insights
Based on Drug Class, TNF inhibitors currently dominate over JAK inhibitors, aminosalicylates, and corticosteroids. This dominance is driven by their efficacy, advanced therapeutic profiles, and the growing need for targeted treatments for IBD. TNF inhibitors, such as infliximab and adalimumab, have become the cornerstone of treatment for both Crohn’s disease and ulcerative colitis. These biologic agents target tumor necrosis factor-alpha (TNF-α), a cytokine that plays a central role in the inflammatory process of IBD. The effectiveness of TNF inhibitors in reducing inflammation, promoting mucosal healing, and improving patient outcomes has made them a preferred choice in the management of IBD. Their ability to induce and maintain remission in patients with moderate to severe forms of IBD contributes to their dominant position in the market.
The success of TNF inhibitors is reflected in their widespread use and the significant market share they command. These drugs are often prescribed when conventional treatments, such as aminosalicylates and corticosteroids, are insufficient. TNF inhibitors provide an advanced therapeutic option for patients who have not responded adequately to first-line treatments, making them a critical component of the IBD drug landscape in Japan.
In comparison, JAK inhibitors, which include medications like tofacitinib, are emerging treatments that offer a novel approach to managing IBD. JAK inhibitors work by interfering with the Janus kinase (JAK) signaling pathways involved in inflammation. Although these drugs show promise and have been gaining traction, they are still relatively new to the market compared to established TNF inhibitors. Their adoption is increasing, but they have not yet reached the same level of dominance as TNF inhibitors. Aminosalicylates, such as mesalamine, are another class of drugs used primarily in the treatment of mild to moderate ulcerative colitis. While they are effective for managing inflammation and maintaining remission, their role is somewhat limited compared to the more potent TNF inhibitors. Aminosalicylates are often used as a first-line treatment, but they do not offer the same level of efficacy in severe cases of IBD as TNF inhibitors do.
Regional Insights
In the Japan Inflammatory Bowel Disease (IBD) drugs market, the Kanto region is the leading area, driven by its significant healthcare infrastructure, large population base, and advanced medical research facilities. The Kanto region, which includes major metropolitan areas such as Tokyo and Yokohama, represents a substantial share of the IBD drug market due to several key factors. The Kanto region is home to the largest concentration of healthcare institutions in Japan. Tokyo, as the capital city, hosts numerous prestigious hospitals, specialized clinics, and research centers dedicated to gastrointestinal diseases. These facilities are equipped with cutting-edge diagnostic tools and treatment technologies, which facilitates the comprehensive management of IBD. The presence of leading medical institutions enhances the availability and adoption of advanced IBD therapies, including biologics and targeted treatments.
The Kanto region's large population contributes significantly to the market demand for IBD drugs. With Tokyo being the most populous city in Japan, the prevalence of IBD is higher due to the larger number of residents, including those who may suffer from chronic conditions such as Crohn's disease and ulcerative colitis. The high population density leads to a greater number of diagnoses and, consequently, a higher demand for IBD medications. This urban environment also supports a higher volume of outpatient and inpatient services, including the management of complex and severe cases of IBD. The Kanto region benefits from its robust healthcare infrastructure, which includes extensive networks of pharmacies and healthcare providers. The accessibility of specialized medical care and the availability of a wide range of IBD drugs contribute to the region's dominance in the market. Patients in Kanto have better access to innovative treatments and clinical trials, which further drives the adoption of new and advanced therapies.
Key Market Players
• AbbVie GK
• JCR Pharmaceuticals Co., Ltd.
• Janssen Pharmaceuticals K.K.
• Asahi Kasei Pharma Corporation
• Sun Pharma Japan Limited
• Kyowa Pharmaceutical Industry Co., Ltd.
• Santen Pharmaceutical Co., Ltd.
• Otsuka Pharmaceutical Co., Ltd.
• Senju Pharmaceutical Co., Ltd.
• Taisho Pharmaceutical Co., Ltd.
Report Scope:
In this report, the Japan Inflammatory Bowel Disease (IBD) Drugs Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:
• Japan Inflammatory Bowel Disease (IBD) Drugs Market, By Disease Type:
o Crohn’s Disease
o Ulcerative Colitis
• Japan Inflammatory Bowel Disease (IBD) Drugs Market, By Drug Class:
o TNF Inhibitors
o JAK Inhibitors
o Aminosalicylates
o Corticosteroids
o Others
• Japan Inflammatory Bowel Disease (IBD) Drugs Market, By Route of Administration:
o Oral
o Parenteral
• Japan Inflammatory Bowel Disease (IBD) Drugs Market, By End User:
o Hospital Pharmacies
o Online Pharmacies
o Retail Pharmacies
• Japan Inflammatory Bowel Disease (IBD) Drugs Market, By Region:
o Hokkaido
o Tohoku
o Kanto
o Chubu
o Kansai
o Chugoku
o Shikoku
o Kyushu
Competitive Landscape
Company Profiles: Detailed analysis of the major companies present in the Japan Inflammatory Bowel Disease (IBD) Drugs Market.
Available Customizations:
Japan Inflammatory Bowel Disease (IBD) Drugs Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:
Company Information
• Detailed analysis and profiling of additional market players (up to five).
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Table of Contents
1. Product Overview
1.1. Market Definition
1.2. Scope of the Market
1.2.1. Markets Covered
1.2.2. Years Considered for Study
1.2.3. Key Market Segmentations
2. Research Methodology
2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validations
2.7. Assumptions and Limitations
3. Executive Summary
3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends
4. Voice of Customer
5. Japan Inflammatory Bowel Disease (IBD) Drugs Market Outlook
5.1. Market Size & Forecast
5.1.1. By Value
5.2. Market Share & Forecast
5.2.1. By Disease Type (Crohn’s Disease and Ulcerative Colitis)
5.2.2. By Drug Class (TNF Inhibitors, JAK Inhibitors, Aminosalicylates, Corticosteroids, and Others)
5.2.3. By Route of Administration (Oral and Parenteral)
5.2.4. By End User (Hospital Pharmacies, Online Pharmacies, and Retail Pharmacies)
5.2.5. By Region
5.2.6. By Company (2024)
5.3. Market Map
6. Hokkaido Inflammatory Bowel Disease (IBD) Drugs Market Outlook
6.1. Market Size & Forecast
6.1.1. By Value
6.2. Market Share & Forecast
6.2.1. By Disease Type
6.2.2. By Drug Class
6.2.3. By Route of Administration
6.2.4. By End User
7. Tohoku Inflammatory Bowel Disease (IBD) Drugs Market Outlook
7.1. Market Size & Forecast
7.1.1. By Value
7.2. Market Share & Forecast
7.2.1. By Disease Type
7.2.2. By Drug Class
7.2.3. By Route of Administration
7.2.4. By End User
8. Kanto Inflammatory Bowel Disease (IBD) Drugs Market Outlook
8.1. Market Size & Forecast
8.1.1. By Value
8.2. Market Share & Forecast
8.2.1. By Disease Type
8.2.2. By Drug Class
8.2.3. By Route of Administration
8.2.4. By End User
9. Chubu Inflammatory Bowel Disease (IBD) Drugs Market Outlook
9.1. Market Size & Forecast
9.1.1. By Value
9.2. Market Share & Forecast
9.2.1. By Disease Type
9.2.2. By Drug Class
9.2.3. By Route of Administration
9.2.4. By End User
10. Kansai Inflammatory Bowel Disease (IBD) Drugs Market Outlook
10.1. Market Size & Forecast
10.1.1. By Value
10.2. Market Share & Forecast
10.2.1. By Disease Type
10.2.2. By Drug Class
10.2.3. By Route of Administration
10.2.4. By End User
11. Chugoku Inflammatory Bowel Disease (IBD) Drugs Market Outlook
11.1. Market Size & Forecast
11.1.1. By Value
11.2. Market Share & Forecast
11.2.1. By Disease Type
11.2.2. By Drug Class
11.2.3. By Route of Administration
11.2.4. By End User
12. Shikoku Inflammatory Bowel Disease (IBD) Drugs Market Outlook
12.1. Market Size & Forecast
12.1.1. By Value
12.2. Market Share & Forecast
12.2.1. By Disease Type
12.2.2. By Drug Class
12.2.3. By Route of Administration
12.2.4. By End User
13. Kyushu Inflammatory Bowel Disease (IBD) Drugs Market Outlook
13.1. Market Size & Forecast
13.1.1. By Value
13.2. Market Share & Forecast
13.2.1. By Disease Type
13.2.2. By Drug Class
13.2.3. By Route of Administration
13.2.4. By End User
14. Market Dynamics
14.1. Drivers
14.2. Challenges
15. Market Trends & Developments
15.1. Merger & Acquisition (If Any)
15.2. Product Launches (If Any)
15.3. Recent Developments
16. Japan Inflammatory Bowel Disease (IBD) Drugs Market: SWOT Analysis
17. Porter’s Five Forces Analysis
17.1. Competition in the Industry
17.2. Potential of New Entrants
17.3. Power of Suppliers
17.4. Power of Customers
17.5. Threat of Substitute Products
18. Competitive Landscape
18.1. AbbVie GK
18.1.1. Business Overview
18.1.2. Company Snapshot
18.1.3. Products & Services
18.1.4. Financials (As Reported)
18.1.5. Recent Developments
18.1.6. Key Personnel Details
18.1.7. SWOT Analysis
18.2. JCR Pharmaceuticals Co., Ltd.
18.3. Janssen Pharmaceuticals K.K.
18.4. Asahi Kasei Pharma Corporation
18.5. Sun Pharma Japan Limited
18.6. Kyowa Pharmaceutical Industry Co., Ltd.
18.7. Santen Pharmaceutical Co., Ltd.
18.8. Otsuka Pharmaceutical Co., Ltd.
18.9. Senju Pharmaceutical Co., Ltd.
18.10. Taisho Pharmaceutical Co., Ltd.
19. Strategic Recommendations
20. About Us & Disclaimer