Summary

Bioreactors Market: Industry Trends and Global Forecasts, till 2035 - Distribution by Fabrication Material (Glass, Stainless Steel and Single use), Type of Bioprocess (Batch, Fed-batch and Continuous), Type of Biologic (Antibodies, Vaccines, Cell Therapies and Other Biologics), and Key Geographical Regions (North America, Europe, Asia-Pacific, and Rest of the World)
Report Link: https://www.rootsanalysis.com/reports/bioreactors-market.html
The Bioreactors Market is valued at USD 16.7 billion in 2024 growing at a CAGR of 11.1% during the forecast period 2024-2035.

Bioreactors represent specialized vessels employed in upstream biomanufacturing to foster the growth of cells and tissues under precisely controlled conditions. These conditions encompass factors like temperature, pH, pressure, aeration, and nutrient levels, all aimed at optimizing the environment for live cells or cellular components. The primary goal is to facilitate the conversion of substrates into a diverse array of biological products. These products span from therapeutic proteins such as vaccines, fusion proteins, antibodies, hormones, interleukins, and enzymes to cutting-edge medicinal products like cell-based and oligonucleotide-based therapies, retroviral vectors for gene therapy, and sophisticated in vitro models mimicking 2D and 3D tissue constructs, essential for drug discovery research. Typically, these bioreactors, often cylindrical and made of stainless steel, vary in size from milliliters to several liters, tailored to different bioprocessing needs and operational modes.

The surge in global demand for biopharmaceutical products has significantly propelled the growth of the bioprocessing supplies market. As companies either establish their own biopharmaceutical manufacturing facilities or opt to outsource production to specialized organizations, the demand for clinical and commercial-scale bioreactors has skyrocketed. Current estimates, including both in-house and outsourced capacities, indicate a global bioreactors capacity exceeding 13 million liters. Given this immense demand, the bioreactors market has evolved into a competitive arena, featuring numerous active companies boasting expertise in designing, engineering, and manufacturing a wide spectrum of bioreactors tailored to diverse applications. Offerings range from traditional stainless-steel bioreactors to disposable/single-use bioreactors, stirred-tank bioreactors, small-scale bioreactors, air lift bioreactors, perfusion bioreactors, bubble column bioreactors, and photobioreactors.


Key Market Segments
Fabrication Material
Stainless Steel
Single Use
Glass
Type of Bioprocess
Batch and Fed-batch
Continuous
Type of Biologic
Antibodies
Vaccines
Cell Therapies
Other Biologics
Key Geographical Regions
North America
Europe
Asia-Pacific
Rest of the World
Research Coverage:
A comprehensive analysis of the overall market landscape of companies manufacturing bioreactors, based on several relevant parameters, such as year of establishment, company size (in terms of number of employees), region of headquarters, geographical reach (North America, Europe, Asia-Pacific and Rest of the World), capacity (micro-mini, small-scale, bench-scale, lab-scale, pilot-scale and large-scale), scale of operation (preclinical, clinical and commercial), scalability, type of bioprocess (batch, fed-batch and continuous), type of cell culture (2D cell culture, 3D cell culture and 4D cell culture), mode of operation (manual, semi-automatic and automatic) and type of end user (academic institutes and research laboratories, biopharmaceutical and pharmaceutical industries, contract manufacturing organizations, and contract research organizations).
Comprehensives company competitiveness analysis of bioreactor manufacturers based on manufacturer strength (in terms of years of experience and company size), portfolio strength (considering geographical reach, number of products in portfolio, type of bioreactor, capacity, scale of operation, scalability, type of bioprocess, type of cell culture, mode of operation and end users).
Comprehensive company profiles of leading players manufacturing bioreactors (shortlisted on the basis of cumulative strength of manufacturers and product portfolio); each profile includes a brief overview of the company, along with information on its financial information (if available), product portfolio, recent developments and an informed future outlook.
A projection of the global installed capacity of bioreactors for biologics, compiled from data sourced from various publicly available industry outlets. This estimation also includes a breakdown of the available capacity categorized by fabrication material (glass, stainless steel, and single-use), cell culture source (mammalian, microbial, and others), reactor volume (less than 2,000 L, 2,000 to 5,000 L, 5,001 to 10,000 L, and over 10,000 L), manufacturer type (in-house, hybrid, and Contract Manufacturing Organizations [CMOs]), and major geographical regions (North America, Europe, Asia-Pacific, and Rest of the World).
A case study on the market landscape of bioprocess controllers and automation systems, providing information on scale of operation (laboratory, clinical, and commercial), key features (scalability / ease to use, visual data display, remote accessibility, built-in system control sensors, expansive I/O compatibility and provisions for alarms / alerts), compatibility with bioreactor system (stirred tank (glass), single use bioreactor, stirred tank (steel), rocking motion), type of bioprocess (batch, fed-batch and perfusion), and type of process controlled (cell cultivation and microbial fermentation). In addition, the chapter presents details of companies involved in the development of bioprocess control software, upstream and downstream controllers, including information on their year of establishment, company size, and location of headquarters.
A comprehensive market forecast analysis has been conducted to assess the current market size and future prospects for the bioreactors market over the coming 11 years. Utilizing multiple parameters and anticipated adoption trends, coupled with primary validations, we have developed informed estimates for market size within the forecast period spanning from 2024 to 2035. This chapter presents detailed projections of both current and future opportunities within the market, segmented across various factors including fabrication material (glass, stainless steel, and single-use), bioprocess type (batch, fed-batch, and continuous), types of biologics (such as antibodies, vaccines, cell therapies, and other biologics), and key geographical regions (North America, Europe, Asia-Pacific, and Rest of the World).
Key Benefits of Buying this Report
The report offers market leaders and newcomers valuable insights into revenue estimations for both the overall market and its sub-segments.
Stakeholders can utilize the report to enhance their understanding of the competitive landscape, allowing for improved business positioning and more effective go-to-market strategies.
The report provides stakeholders with a pulse on the Bioreactors Market, furnishing them with essential information on significant market drivers, barriers, opportunities, and challenges.
Leading Market Companies
Applikon Biotechnology
Bionet
Cytiva
Eppendorf
Merck
Ollital Technology
Parr Instrument Company
Sartorius
Shanghai Bailun Biological Technology
Solaris Biotech
Solida Biotech
Zhengzhou Laboao Instrument Equipment (LABAO)

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Table of Contents

1. PREFACE
1.1. Introduction
1.2. Key Market Insights
1.3. Scope of the Report
1.4. Research Methodology
1.5. Frequently Asked Questions
1.6. Chapter Outlines

2. EXECUTIVE SUMMARY

3. INTRODUCTION
3.1. Chapter Overview
3.2. Overview of Bioreactors
3.3. Components of a Bioreactor
3.4. Types of Bioreactors
3.4.1. Classification based on Type of Bioprocess
3.4.2. Classification based on Mode of Action
3.5. Applications of Bioreactors
3.6. Future Perspectives

4. BIOREACTOR MANUFACTURERS: MARKET LANDSCAPE
4.1. Chapter Overview
4.2. Bioreactor Manufacturers: Overall Market Landscape
4.2.1. Analysis by Year of Establishment
4.2.2. Analysis by Company Size
4.2.3. Analysis by Region of Headquarters
4.2.4. Analysis by Location of Headquarters
4.2.5. Analysis by Year of Establishment and Region of Headquarters
4.2.6. Analysis by Company Size and Region of Headquarters
4.2.7. Analysis by Year of Establishment, Company Size and Region of Headquarters
4.2.8. Analysis by Geographical Reach
4.2.9. Analysis by Region of Headquarters and Geographical Reach
4.2.10. Analysis by Capacity
4.2.11. Analysis by Scale of Operation
4.2.12. Analysis by Scalability
4.2.13. Analysis by Type of Bioprocess
4.2.14. Analysis by Type of Cell Culture
4.2.15. Analysis by Mode of Operation
4.2.16. Analysis by Type of End-user

5. COMPANY COMPETITIVENESS ANALYSIS
5.1. Chapter Overview
5.2. Assumptions / Key Parameters
5.3. Methodology

5.4. Company Competitiveness Analysis: Small Companies
5.4.1. Company Competitiveness Analysis: Small Companies based in North America
5.4.2. Company Competitiveness Analysis: Small Companies based in Europe
5.4.3. Company Competitiveness Analysis: Small Companies based in Asia-Pacific and Rest of the World

5.5. Company Competitiveness Analysis: Mid-sized Companies
5.5.1. Company Competitiveness Analysis: Mid-sized Companies based in North America
5.5.2. Company Competitiveness Analysis: Mid-sized Companies based in Europe
5.5.3. Company Competitiveness Analysis: Mid-sized Companies based in Asia-Pacific and Rest of the World

5.6. Company Competitiveness Analysis: Large and Very Large Companies

6. COMPANY PROFILES
6.1. Chapter Overview
6.2. Applikon Biotechnology (acquired by Getinge)
6.2.1. Company Overview
6.2.2. Product Portfolio
6.2.3. Recent Developments and Future Outlook

6.3. Bionet
6.3.1. Company Overview
6.3.2. Product Portfolio
6.3.3. Recent Developments and Future Outlook

6.4. Cytiva
6.4.1. Company Overview
6.4.2. Financial Information
6.4.3. Product Portfolio
6.4.4. Recent Developments and Future Outlook

6.5. Eppendorf
6.5.1. Company Overview
6.5.2. Financial Information
6.5.3. Product Portfolio
6.5.4. Recent Developments and Future Outlook

6.6. Merck
6.6.1. Company Overview
6.6.2. Financial Information
6.6.3. Product Portfolio
6.6.4. Recent Developments and Future Outlook

6.7. Ollital Technology
6.7.1. Company Overview
6.7.2. Product Portfolio
6.7.3. Recent Developments and Future Outlook

6.8. Parr Instrument Company
6.8.1. Company Overview
6.8.2. Product Portfolio
6.8.3. Recent Developments and Future Outlook

6.9. Sartorius
6.9.1. Company Overview
6.9.2. Financial Information
6.9.3. Product Portfolio
6.9.4. Recent Developments and Future Outlook

6.10. Shanghai Bailun Biological Technology
6.10.1. Company Overview
6.10.2. Product Portfolio
6.10.3. Recent Developments and Future Outlook

6.11. Solaris Biotech (acquired by Donaldson Company)
6.11.1. Company Overview
6.11.2. Product Portfolio
6.11.3. Recent Developments and Future Outlook

6.12. Solida Biotech
6.12.1. Company Overview
6.12.2. Product Portfolio
6.12.3. Recent Developments and Future Outlook

6.13. Zhengzhou Laboao Instrument Equipment (LABAO)
6.13.1. Company Overview
6.13.2. Product Portfolio
6.13.3. Recent Developments and Future Outlook

7. CAPACITY ANALYSIS
7.1. Chapter Overview
7.2. Key Assumptions and Methodology
7.2.1 Bioreactors s: Global Installed Capacity of Biologics
7.2.1.1. Analysis by Fabrication Material
7.2.1.2. Analysis by Source of Cell Culture
7.2.1.3. Analysis by Reactor Volume
7.2.1.4. Analysis by Type of Manufacturer
7.2.1.5. Analysis by Key Geographical Regions

7.3. Concluding Remarks

8. CASE STUDY: BIOPROCESS CONTROLLERS AND AUTOMATION SYSTEMS
8.1. Chapter Overview
8.2. Bioprocess Control Software: Overall Market Landscape
8.2.1. Analysis by Scale of Operation
8.2.2. Analysis by Key Features
8.2.3. Analysis by Compatibility with System
8.2.4. Analysis by Type of Process Controlled

8.3. Bioprocess Control Software Developers: Overall Market Landscape
8.3.1. Analysis by Year of Establishment
8.3.2. Analysis by Company Size
8.3.3. Analysis by Location of Headquarters

8.4. Upstream Controllers: Overall Market Landscape
8.4.1. Analysis by Scale of Operation
8.4.2. Analysis by Key Features
8.4.3. Analysis by Compatibility with Bioreactor System
8.4.4. Analysis by Type of Bioprocess
8.4.5. Analysis by Type of Process Controlled

8.5. Upstream Controller Developers: Overall Market Landscape
8.5.1. Analysis by Year of Establishment
8.5.2. Analysis by Company Size
8.5.3. Analysis by Location of Headquarters

8.6. Downstream Controller Systems: Overall Market Landscape
8.6.1. Analysis by Scale of Operation
8.6.2. Analysis by Key Features
8.6.3. Analysis by Type of System
8.6.4. Analysis by Type of Bioprocess
8.6.5. Analysis by Application Area

8.7. Downstream Controller System Developers: Overall Market Landscape
8.7.1. Analysis by Year of Establishment
8.7.2. Analysis by Company Size
8.7.3. Analysis by Location of Headquarters

9. MARKET FORECAST
9.1. Chapter Overview
9.2. Key Assumptions and Forecast Methodology

9.3. Global Bioreactors Market, 2023-2035: Distribution by Fabrication Material
9.3. 1. Global Glass Bioreactors Market, 2023-2035
9.3. 2. Global Stainless Steel Bioreactors Market, 2023-2035
9.3. 3. Global Single use Bioreactors Market, 2023-2035

9.4. Global Bioreactors Market, 2023-2035: Distribution by Type of Bioprocess
9.3.3.1. Global Bioreactors Market for Batch and Fed-batch Process, 2023-2035
9.3.3.2. Global Bioreactors Market for Continuous Process, 2023-2035

9.3.4. Global Bioreactors Market, 2023-2035: Distribution by Type of Biologic
9.3.4.1. Global Bioreactors Market for Antibodies, 2023-2035
9.3.4.2. Global Bioreactors Market for Vaccines, 2023-2035
9.3.4.3. Global Bioreactors Market for Cell Therapies, 2023-2035
9.3.4.4. Global Bioreactors Market for Other Biologics, 2023-2035

9.3.5. Global Bioreactors Market, 2023-2035: Distribution by Key Geographical Regions
9.3.5.1. Global Bioreactors Market in North America, 2023-2035
9.3.5.2. Global Bioreactors Market in Europe, 2023-2035
9.3.5.3. Global Bioreactors Market in Asia-Pacific, 2023-2035
9.3.5.4. Global Bioreactors Market in Rest of the World, 2023-2035

10. EXECUTIVE INSIGHTS

11. CONCLUDING REMARKS

12. APPENDIX 1: TABULATED DATA

13. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

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List of Tables/Graphs

Figure 2.1 Executive Summary: Overall Market Landscape
Figure 2.2 Executive Summary: Capacity Analysis
Figure 2.3 Executive Summary: Market Forecast
Figure 3.1 Components of a Bioreactor
Figure 3.2 Types of Bioreactors (based on Type of Bioprocess)
Figure 3.3 Types of Bioreactors (based on Mode of Action)
Figure 3.4 Industries Employing Bioreactors
Figure 3.5 Applications of Bioreactors in Pharmaceutical Industry
Figure 4.1 Bioreactor Manufacturers: Distribution by Year of Establishment
Figure 4.2 Bioreactor Manufacturers: Distribution by Company Size
Figure 4.3 Bioreactor Manufacturers: Distribution by Region of Headquarters
Figure 4.4 Bioreactor Manufacturers: Distribution by Location of Headquarters
Figure 4.5 Bioreactor Manufacturers: Distribution by Year of Establishment and Region of Headquarters
Figure 4.6 Bioreactor Manufacturers: Distribution by Company Size and Region of Headquarters
Figure 4.7 Bioreactor Manufacturers: Distribution by Year of Establishment, Company Size and Region of Headquarters
Figure 4.8 Bioreactor Manufacturers: Distribution by Geographical Reach
Figure 4.9 Bioreactor Manufacturers: Distribution by Region of Headquarters and Geographical Reach
Figure 4.10 Bioreactor Manufacturers: Distribution by Capacity
Figure 4.11 Bioreactor Manufacturers: Distribution by Scale of Operation
Figure 4.12 Bioreactor Manufacturers: Distribution by Scalability
Figure 4.13 Bioreactor Manufacturers: Distribution by Type of Bioprocess
Figure 4.14 Bioreactor Manufacturers: Distribution by Type of Cell Culture
Figure 4.15 Bioreactor Manufacturers: Distribution by Mode of Operation
Figure 4.16 Bioreactor Manufacturers: Distribution by Type of End-user
Figure 5.1 Competitiveness Analysis: Small Companies
Figure 5.2 Competitiveness Analysis: Small Companies based in North America
Figure 5.3 Competitiveness Analysis: Small Companies based in Europe
Figure 5.4 Competitiveness Analysis: Small Companies based in Asia-Pacific and Rest of the World
Figure 5.5 Competitiveness Analysis: Mid-sized Companies
Figure 5.6 Competitiveness Analysis: Mid-sized Companies based in North America
Figure 5.7 Competitiveness Analysis: Mid-sized Companies based in Europe
Figure 5.8 Competitiveness Analysis: Mid-sized Companies based in Asia-Pacific and Rest of the World
Figure 5.9 Competitiveness Analysis: Large and Very Large Companies
Figure 5.10 Competitiveness Analysis of Bioreactor Manufacturers: Competitiveness Score of Top Players
Figure 6.1 Cytiva: Annual Revenues, FY 2017-FY 2021 (USD Million)
Figure 6.2 Eppendorf: Annual Revenues, FY 2017-FY 2021 (EUR Million)
Figure 6.3 Merck: Annual Revenues, FY 2017-FY 2022 (EUR Billion)
Figure 6.4 Sartorius: Annual Revenues, FY 2017-FY 2022 (EUR Billion)
Figure 7.1 Global Installed Bioreactors Capacity (by Million Liters): Distribution by Fabrication Material
Figure 7.2 Global Installed Bioreactors Capacity (by Million Liters): Distribution by Source of Cell Culture
Figure 7.3 Global Installed Bioreactors Capacity (by Million Liters): Distribution by Reactor Volume
Figure 7.4 Global Installed Bioreactors Capacity (by Million Liters): Distribution by Type of Manufacturer
Figure 7.5 Global Installed Bioreactors Capacity (by Million Liters): Distribution by Key Geographical Regions
Figure 8.1 Bioprocess Control Software: Distribution by Scale of Operation
Figure 8.2 Bioprocess Control Software: Distribution by Key Features
Figure 8.3 Bioprocess Control Software: Distribution by Compatibility with System
Figure 8.4 Bioprocess Control Software: Distribution by Type of Process Controlled
Figure 8.5 Bioprocess Control Software Developers: Distribution by Year of Establishment
Figure 8.6 Bioprocess Control Software Developers: Distribution by Company Size
Figure 8.7 Bioprocess Control Software Developers: Distribution by Location of Headquarters
Figure 8.8 Upstream Controllers: Distribution by Scale of Operation
Figure 8.9 Upstream Controllers: Distribution by Key Features
Figure 8.10 Upstream Controllers: Distribution by Compatibility with Bioreactor System
Figure 8.11 Upstream Controllers: Distribution by Type of Bioprocess
Figure 8.12 Upstream Controllers: Distribution by Type of Process Controlled
Figure 8.13 Upstream Controller Developers: Distribution by Year of Establishment
Figure 8.14 Upstream Controller Developers: Distribution by Company Size
Figure 8.15 Upstream Controller Developers: Distribution by Location of Headquarters
Figure 8.16 Downstream Controller Systems: Distribution by Scale of Operation
Figure 8.17 Downstream Controller Systems: Distribution by Key Features
Figure 8.18 Downstream Controller Systems: Distribution by Type of System
Figure 8.19 Downstream Controller Systems: Distribution by Type of Bioprocess
Figure 8.20 Downstream Controller Systems: Distribution by Application Area
Figure 8.21 Downstream Controller System Developers: Distribution by Year of Establishment
Figure 8.22 Downstream Controller System Developers: Distribution by Company Size
Figure 8.23 Downstream Controller System Developers: Distribution by Location of Headquarters
Figure 9.1 Global Bioreactors Market, 2023-2035 (USD Billion)
Figure 9.2 Global Bioreactors Market, 2023-2035: Distribution by Fabrication Material
Figure 9.3 Global Glass Bioreactors Market, 2023-2035
Figure 9.4 Global Stainless Steel Bioreactors Market, 2023-2035
Figure 9.5 Global Single use Bioreactors Market, 2023-2035
Figure 9.6 Global Bioreactors Market, 2023-2035: Distribution by Type of Bioprocess
Figure 9.7 Global Bioreactors Market for Batch and Fed-batch Process, 2023-2035
Figure 9.8 Global Bioreactors Market for Continuous Process, 2023-2035
Figure 9.9 Global Bioreactors Market, 2023-2035: Distribution by Type of Biologic
Figure 9.10 Global Bioreactors Market for Antibodies, 2023-2035
Figure 9.11 Global Bioreactors Market for Vaccines, 2023-2035
Figure 9.12 Global Bioreactors Market for Cell Therapies, 2023-2035
Figure 9.13 Global Bioreactors Market for Other Biologics, 2023-2035
Figure 9.14 Global Bioreactors Market, 2023-2035: Distribution by Key Geographical Regions
Figure 9.15 Bioreactors Market in North America, 2023-2035
Figure 9.16 Bioreactors Market in Europe, 2023-2035
Figure 9.17 Bioreactors Market in Asia-Pacific, 2023-2035
Figure 9.18 Bioreactors Market in Rest of the World, 2023-2035
Figure 11.1 Concluding Remarks: Overall Market Landscape of Bioreactor Manufacturers
Figure 11.2 Concluding Remarks: Geographical Distribution of Bioreactor Manufacturers
Figure 11.3 Concluding Remarks: Capacity Analysis
Figure 11.4 Concluding Remarks: Market Forecast