Summary

Overview
Global physiological saline market reached US$ YY million in 2022 and is expected to reach US$ YY million by 2030, growing at a CAGR of YY% during the forecast period 2023-2030.
Physiological saline also called normal saline solution, is a 0.9% sodium chloride solution, called physiological because it is an isotonic solution, with an osmotic pressure equivalent to that of body fluids such as blood and tears under normal conditions. To create physiological saline, dissolve 9g of pure salt with 1 liter of distilled water. Although the ingredients and preparation are simple, in order to create a standard physiological saline product, it is necessary to ensure a lot of factors from salt raw materials to ensure cleanliness, no impurities, no contamination and no water.
Moreover, physiological saline has many uses, the form of physiological saline solution for infusion is used in cases where the body needs to replenish water and electrolytes such as when vomiting and diarrhea. When infusion, the doctor can prescribe to physiological saline solution drugs with therapeutic effects, the infusion rate is adjusted to the appropriate level so that the drug enters the patient's body to reach the optimal concentration. Physiological saline helps clean surface impurities and moisturizes and also soothes the eyes.
Market Dynamics: Drivers
Increasing adoption of physiological saline in surgical procedures
The increasing adoption of physiological saline in surgical procedures is expected to drive the market over the forecast period. Physiological saline is commonly used as an intravenous fluid during surgical procedures to maintain hydration, electrolyte balance, and blood volume. Saline is used for cleaning and irrigating wounds during surgery to prevent infection and promote healing. Physiological saline serves as a conductive medium in certain surgical procedures like electrosurgery.
The increasing number of surgeries is expected to increase the demand for physiological saline. For instance, according to the National Institute of Health (NIH), 2020, globally, a staggering 310 million major surgeries are performed each year, around 40 to 50 million in the USA and 20 million in Europe. It is estimated that 1–4% of these patients will die, up to 15% will have serious postoperative morbidity and 5–15% will be readmitted within 30 days.
Moreover, during the surgery, surgeons use saline to flush tissues during various procedures like organ transplants. Physiological saline is isotonic, meaning it has a similar salt concentration as human cells, making it safe for various applications including during surgical procedures. Its composition reduces the risk of adverse reactions or side effects, making it a preferred choice in surgical settings. Additionally, saline is also used as a diluent for medications administered during surgery.
Further, the increasing prevalence of wounds, dehydration and other acute health disorders, increasing awareness about the physiological salines and increasing adoption of the physiological salines in various applications are the factors expected to drive the market over the forecast period.
Restraints
Factors such as side effects associated with the physiological saline like practice guidelines indicate that normal saline instillation before endotracheal suctioning has more disadvantages, such as desaturation, bronchospasm, dyspnea and ventilator-associated pneumonia are expected to hamper the market.
Segment Analysis
The global physiological saline market is segmented based on packaging type, application, end-user and region.
The plastic bottle segment accounted for approximately 39.8% of the physiological saline market share
The plastic bottle segment is expected to hold the largest market share over the forecast period. The plastic bottles can be manufactured to meet stringent requirements for sterility, ensuring the safety of the saline solution. Even these plastic saline bottles are more affordable than the others. Also, plastic bottles are lightweight, which makes them easy to handle and transport, which is crucial in medical settings.
Additionally, plastic bottles are easy to squeeze by facilitating the controlled administration of saline solutions during surgical and other procedures. Plastic bottles are often designed for single use, this reduces the risk of contamination and simplifies disposal after use. Transparent or translucent plastic bottles allow to visually inspect the contents for clarity and purity. Plastic bottles are often designed for single use, reducing the risk of contamination.
Further, their wide availability and acceptability helps to hold the largest market share. Plastic saline bottles are durable and less prone to breakage than other packaging devices such as glass containers, this further reduces the risk of accidents in hospital and clinical environments. In addition, their wide adoption also increases the demand for the plastic saline bottle.
Geographical Analysis
North America accounted for approximately 39.8% of the market share
North America region is expected to hold the largest market share over the forecast period owing to the strong presence of major players and increasing adoption. North America especially the United States is a hub for its presence of major players such as pharmaceutical companies and medical device companies. The presence of major players actively focussing on manufacturing more amount of physiological salines, further recovers the shortages of the salines in the region.
Furthermore, increasing adoption of the physiological salines in the region is also expected to drive the market in the region. The region is known for the increasing aging population and the increasing prevalence of many acute care disorders, further increasing the demand for the adoption of salines. Additionally, the region also experiences a high volume of medical procedures, including surgeries, which contributes to the demand for physiological saline used in various medical applications.
For instance, according to the NPR Organization, IV fluids are among the most common medical interventions worldwide. Several kinds are available, but one called normal saline or physiological saline is by far the most popular. Over 200 million liters are used every year in the United States for various medical procedures.
Competitive Landscape
The major global players in the physiological saline market include Enzo Life Sciences, Inc., Thermo Fisher Scientific Inc., Merck KGaA, Adipogen Life Sciences, Geno Technology Inc., LABORATORIOS ERN, S.A., Grifols, S.A., Schwitz Biotech, Eurocrit Labs International and Cepham Life Sciences among others.
COVID-19 Impact Analysis
The COVID-19 pandemic significantly impacted the global physiological saline market. During the pandemic, the demand for physiological saline has increased. The COVID-19 pandemic led to a surge in demand for medical supplies and equipment including physiological saline. Hospitals and healthcare clinics faced increased patient loads especially those with severe respiratory symptoms, necessitating greater use of these physiological saline. The pandemic also disrupted the supply chain of the physiological saline globally.
Market Segmentation
By Packaging Type
• Plastic Bottle
• Glass Bottle
• Flexible Bag
By Application
• Dehydration
• Metabolic Alkalosis
• Mild Sodium Depletion
• Wound Cleansing
• Skin Abrasions and Burns
• Others
By End-User
• Hospitals
• Specialty Clinics
• Ambulatory Surgical Centers
• Others
By Region
• North America
o U.S.
o Canada
o Mexico
• Europe
o Germany
o U.K.
o France
o Spain
o Italy
o Rest of Europe
• South America
o Brazil
o Argentina
o Rest of South America
• Asia-Pacific
o China
o India
o Japan
o Australia
o Rest of Asia-Pacific
• Middle East and Africa
Why Purchase the Report?
• To visualize the global physiological saline market segmentation based on packaging type, application, end-user and region as well as understand key commercial assets and players.
• Identify commercial opportunities by analyzing trends and co-development
• Excel data sheet with numerous data points of physiological saline market-level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as excel consisting of key products of all the major players.
The global physiological saline market report would provide approximately 61 tables, 61 figures, and 187 Pages.
Target Audience 2023
• Manufacturers/ Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies

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