NAがん免疫療法市場 - 2035年までの産業動向と予測NA Cancer Immunotherapy Market - Industry Trends and Forecast to 2035 北米のがん免疫療法市場は、2023年の521億5,929万米ドルから2031年には1,478億2,458万米ドルに達し、2024年から2031年の予測期間中に年平均成長率14.9%で成長すると予測されている。 市場セグメンテーション ... もっと見る
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サマリー北米のがん免疫療法市場は、2023年の521億5,929万米ドルから2031年には1,478億2,458万米ドルに達し、2024年から2031年の予測期間中に年平均成長率14.9%で成長すると予測されている。市場セグメンテーション 北米がん免疫療法市場:製品タイプ別(チェックポイント阻害剤、モノクローナル抗体、ワクチン、細胞療法、免疫調節剤、がん溶解性ウイルス)、用途別(肺がん、乳がん、メラノーマ、骨髄腫、前立腺がん、卵巣がん、S.,産業動向と2031年までの予測 北米がん免疫療法市場ダイナミクスの概要 推進要因 - がん罹患率の上昇 抑制要因 - 免疫関連の有害事象の増加 機会 - 併用療法への傾向の高まり 市場プレイヤー 北米のがん免疫療法市場で事業を展開する主な市場参入企業は以下の通りである: - メルク社 - F.ホフマン・ラ・ロシュ社 - ブリストル・マイヤーズ スクイブ社 - ヤンセンファーマ - アストラゼネカ - ギリアド・サイエンシズ - イーライリリー・アンド・カンパニー - アムジェン社 - ノバルティスAG - GSK - ファイザー - インサイト 目次TABLE OF CONTENTS1 INTRODUCTION 83 1.1 OBJECTIVES OF THE STUDY 83 1.2 MARKET DEFINITION 83 1.3 OVERVIEW OF THE NORTH AMERICA CANCER IMMUNOTHERAPY MARKET 83 1.4 CURRENCY AND PRICING 85 1.5 LIMITATIONS 85 1.6 MARKETS COVERED 85 2 MARKET SEGMENTATION 89 2.1 MARKETS COVERED 89 2.2 GEOGRAPHICAL SCOPE 90 2.3 YEARS CONSIDERED FOR THE STUDY 91 2.4 DBMR TRIPOD DATA VALIDATION MODEL 92 2.5 PRIMARY INTERVIEWS WITH KEY OPINION LEADERS 95 2.6 MULTIVARIATE MODELLING 96 2.7 PRODUCT TYPE SEGMENT LIFELINE CURVE 96 2.8 MARKET END USER COVERAGE GRID 97 2.9 DBMR MARKET POSITION GRID 98 2.10 VENDOR SHARE ANALYSIS 99 2.11 SECONDARY SOURCES 100 2.12 ASSUMPTIONS 100 3 EXECUTIVE SUMMARY 101 4 PREMIUM INSIGHTS 103 4.1 PESTAL ANALYSIS 104 4.2 PORTERS 5 FORCES 105 5 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET: REGULATIONS 106 6 MARKET OVERVIEW 114 6.1 DRIVERS 116 6.1.1 RISING PREVALENCE OF CANCER INCIDENCES 116 6.1.2 RISING TECHNOLOGICAL ADVANCEMENTS 116 6.1.3 INCREASED UNDERSTANDING OF TUMOR MICROENVIRONMENT 117 6.1.4 RISE IN PATIENT AWARENESS AND DEMAND FOR TARGETED TREATMENT 117 6.2 RESTRAINTS 118 6.2.1 INCREASING OCCURRENCE OF IMMUNE-RELATED ADVERSE EVENTS 118 6.2.2 DEVELOPING RESISTANCE TO CANCER TREATMENT 118 6.3 OPPORTUNITIES 119 6.3.1 GROWING TREND TOWARDS COMBINATION THERAPIES 119 6.3.2 RISING INTEGRATION OF ARTIFICIAL INTELLIGENCE AND DIGITAL HEALTH TOOLS 119 6.3.3 DEVELOPMENT OF NEXT-GENERATION IMMUNOTHERAPIES 120 6.4 CHALLENGES 121 6.4.1 LACK OF STANDARDIZATION IN BIOMARKER TESTING 121 6.4.2 COMPLEXITY OF DEVELOPING AND IMPLEMENTING PERSONALIZED MEDICINE 121 7 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY PRODUCT TYPE 122 7.1 OVERVIEW 123 7.2 CHECKPOINT INHIBITORS 126 7.2.1 PROGRAMMED DEATH 1 (PD-1) & PROGRAMMED DEATH LIGAND 1 (PD-L1) 127 7.2.2 CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN-4 (CTLA-4) 127 7.3 MONOCLONAL ANTIBODIES 128 7.3.1 NAKED MONOCLONAL ANTIBODIES 129 7.3.2 CONJUGATED MONOCLONAL ANTIBODIES 129 7.3.3 BISPECIFIC MONOCLONAL ANTIBODIES 129 7.4 VACCINES 130 7.4.1 PROPHYLACTIC VACCINES 131 7.4.2 THERAPEUTIC VACCINES 131 7.5 CELL THERAPIES 131 7.5.1 CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL THERAPY 132 7.5.2 T CELL THERAPY 132 7.6 IMMUNOMODULATORS 132 7.6.1 INTERFERONS 133 7.6.2 INTERLEUKINS 133 7.6.3 GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR 133 7.7 ONCOLYTIC VIRUS 134 8 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY END USER 135 8.1 OVERVIEW 136 8.2 HOSPITALS 139 8.3 ONCOLOGY CLINICS 140 8.4 HOMECARE 140 8.5 OTHERS 141 9 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY DISTRIBUTION CHANNEL 142 9.1 OVERVIEW 143 9.2 DIRECT TENDERS 146 9.3 RETAIL SALES 147 9.4 PHARMACIES 147 9.4.1 HOSPITAL 148 9.4.2 RETAIL 148 9.4.3 ONLINE 148 10 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY FORM 149 10.1 OVERVIEW 150 10.2 INTRAVENOUS (IV) 153 10.3 INTRAMUSCULAR 154 10.4 ORAL 154 11 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY APPLICATION 155 11.1 OVERVIEW 156 11.2 LUNG CANCER 159 11.2.1 CHECKPOINT INHIBITORS 160 11.2.2 MONOCLONAL ANTIBODIES 160 11.2.3 CELL THERAPIES 160 11.2.4 IMMUNOMODULATORS 160 11.3 BREAST CANCER 161 11.3.1 CHECKPOINT INHIBITORS 161 11.3.2 MONOCLONAL ANTIBODIES 161 11.3.3 CELL THERAPIES 162 11.3.4 IMMUNOMODULATORS 162 11.4 MELANOMA 162 11.4.1 CHECKPOINT INHIBITORS 163 11.4.2 MONOCLONAL ANTIBODIES 163 11.4.3 CELL THERAPIES 163 11.4.4 IMMUNOMODULATORS 163 11.4.5 ONCOLYTIC VIRUS 163 11.5 MULTIPLE MYELOMA 164 11.5.1 CHECKPOINT INHIBITORS 164 11.5.2 MONOCLONAL ANTIBODIES 164 11.5.3 CELL THERAPIES 164 11.5.4 IMMUNOMODULATORS 165 11.6 PROSTATE CANCER 165 11.6.1 CHECKPOINT INHIBITORS 165 11.6.2 MONOCLONAL ANTIBODIES 166 11.6.3 CELL THERAPIES 166 11.6.4 IMMUNOMODULATORS 166 11.6.5 VACCINES 166 11.7 OVARIAN CANCER 166 11.7.1 CHECKPOINT INHIBITORS 167 11.7.2 MONOCLONAL ANTIBODIES 167 11.7.3 CELL THERAPIES 167 11.7.4 IMMUNOMODULATORS 167 11.8 CERVICAL CANCER 168 11.8.1 CHECKPOINT INHIBITORS 168 11.8.2 MONOCLONAL ANTIBODIES 168 11.8.3 VACCINES 169 11.8.4 CELL THERAPIES 169 11.8.5 IMMUNOMODULATORS 169 11.9 STOMACH CANCER 169 11.9.1 CHECKPOINT INHIBITORS 170 11.9.2 MONOCLONAL ANTIBODIES 170 11.9.3 CELL THERAPIES 170 11.9.4 IMMUNOMODULATORS 170 11.10 COLORECTAL CANCER 170 11.10.1 CHECKPOINT INHIBITORS 171 11.10.2 MONOCLONAL ANTIBODIES 171 11.10.3 CELL THERAPIES 171 11.10.4 IMMUNOMODULATORS 171 11.11 HEAD AND NECK CANCER 172 11.11.1 CHECKPOINT INHIBITORS 172 11.11.2 MONOCLONAL ANTIBODIES 172 11.11.3 CELL THERAPIES 172 11.11.4 IMMUNOMODULATORS 173 11.12 OTHERS 173 11.12.1 CHECKPOINT INHIBITORS 173 11.12.2 MONOCLONAL ANTIBODIES 173 11.12.3 VACCINES 174 11.12.4 CELL THERAPIES 174 11.12.5 IMMUNOMODULATORS 174 12 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY REGION 175 12.1 NORTH AMERICA 177 12.1.1 U.S. 185 12.1.2 CANADA 193 12.1.3 MEXICO 201 13 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, COMPANY LANDSCAPE 209 13.1 COMPANY SHARE ANALYSIS: NORTH AMERICA 209 14 SWOT ANALYSIS 210 15 COMPANY PROFILES 211 15.1 MERCK & CO., INC. 211 15.1.1 COMPANY SNAPSHOT 211 15.1.2 REVENUE ANALYSIS 211 15.1.3 COMPANY SHARE ANALYSIS 212 15.1.4 PRODUCT PORTFOLIO 212 15.1.5 RECENT DEVELOPMENTS 212 15.2 F. HOFFMANN-LA ROCHE LTD 213 15.2.1 COMPANY SNAPSHOT 213 15.2.2 REVENUE ANALYSIS 213 15.2.3 COMPANY SHARE ANALYSIS 214 15.2.4 PRODUCT PORTFOLIO 214 15.2.5 RECENT DEVELOPMENTS 214 15.3 BRISTOL-MYERS SQUIBB COMPANY 216 15.3.1 COMPANY SNAPSHOT 216 15.3.2 REVENUE ANALYSIS 216 15.3.3 COMPANY SHARE ANALYSIS 217 15.3.4 PRODUCT PORTFOLIO 217 15.3.5 RECENT DEVELOPMENTS 218 15.4 JANSSEN NORTH AMERICA SERVICES, LLC 219 15.4.1 COMPANY SNAPSHOT 219 15.4.2 REVENUE ANALYSIS 219 15.4.3 COMPANY SHARE ANALYSIS 220 15.4.4 PRODUCT PORTFOLIO 220 15.4.5 RECENT DEVELOPMENTS 221 15.5 ASTRAZENECA 222 15.5.1 COMPANY SNAPSHOT 222 15.5.2 REVENUE ANALYSIS 222 15.5.3 COMPANY SHARE ANALYSIS 223 15.5.4 PRODUCT PORTFOLIO 223 15.5.5 RECENT DEVELOPMENTS 224 15.6 ABBVIE INC. 225 15.6.1 COMPANY SNAPSHOT 225 15.6.2 PIPELINE PORTFOLIO 225 15.6.3 RECENT DEVELOPMENTS 225 15.7 AMGEN INC. 226 15.7.1 COMPANY SNAPSHOT 226 15.7.2 REVENUE ANALYSIS 227 15.7.3 PIPELINE PORTFOLIO 227 15.7.4 PRODUCT PORTFOLIO 228 15.7.5 RECENT DEVELOPMENTS 228 15.8 ATARA BIOTHERAPEUTICS, INC. 229 15.8.1 COMPANY SNAPSHOT 229 15.8.2 PIPELINE PORTFOLIO 229 15.8.3 RECENT DEVELOPMENTS 229 15.9 BAYER AG 230 15.9.1 COMPANY SNAPSHOT 230 15.9.2 PIPELINE PORTFOLIO 230 15.9.3 RECENT DEVELOPMENTS 230 15.10 CELLDEX THERAPEUTICS. 232 15.10.1 COMPANY SNAPSHOT 232 15.10.2 PIPELINE PORTFOLIO 232 15.10.3 RECENT DEVELOPMENTS 232 15.11 CELLECTIS 233 15.11.1 COMPANY SNAPSHOT 233 15.11.2 PIPELINE PORTFOLIO 233 15.11.3 RECENT DEVELOPMENTS 233 15.12 GILEAD SCIENCES, INC. 234 15.12.1 COMPANY SNAPSHOT 234 15.12.2 REVENUE ANALYSIS 234 15.12.3 PRODUCT PORTFOLIO 235 15.12.4 RECENT DEVELOPMENTS 235 15.13 GSK PLC. 236 15.13.1 COMPANY SNAPSHOT 236 15.13.2 REVENUE ANALYSIS 236 15.13.3 PRODUCT PORTFOLIO 237 15.13.4 RECENT DEVELOPMENTS 237 15.14 INCYTE. 238 15.14.1 COMPANY SNAPSHOT 238 15.14.2 REVENUE ANALYSIS 238 15.14.3 PRODUCT PORTFOLIO 239 15.14.4 RECENT DEVELOPMENTS 239 15.15 LILLY. 240 15.15.1 COMPANY SNAPSHOT 240 15.15.2 REVENUE ANALYSIS 241 15.15.3 PRODUCT PORTFOLIO 241 15.15.4 RECENT DEVELOPMENTS 242 15.16 NOVARTIS AG 243 15.16.1 COMPANY SNAPSHOT 243 15.16.2 REVENUE ANALYSIS 243 15.16.3 PIPELINE PORTFOLIO 244 15.16.4 PRODUCT PORTFOLIO 244 15.16.5 RECENT DEVELOPMENTS 244 15.17 PFIZER INC. 245 15.17.1 COMPANY SNAPSHOT 245 15.17.2 REVENUE ANALYSIS 245 15.17.3 PRODUCT PORTFOLIO 246 15.17.4 RECENT DEVELOPMENTS 246 16 QUESTIONNAIRE 247 17 RELATED REPORTS 251
SummaryThe North America cancer immunotherapy market is expected to reach USD 147,824.58 million by 2031 from USD 52,159.29 million in 2023, growing at a CAGR of 14.9% during the forecast period of 2024 to 2031. Table of ContentsTABLE OF CONTENTS1 INTRODUCTION 83 1.1 OBJECTIVES OF THE STUDY 83 1.2 MARKET DEFINITION 83 1.3 OVERVIEW OF THE NORTH AMERICA CANCER IMMUNOTHERAPY MARKET 83 1.4 CURRENCY AND PRICING 85 1.5 LIMITATIONS 85 1.6 MARKETS COVERED 85 2 MARKET SEGMENTATION 89 2.1 MARKETS COVERED 89 2.2 GEOGRAPHICAL SCOPE 90 2.3 YEARS CONSIDERED FOR THE STUDY 91 2.4 DBMR TRIPOD DATA VALIDATION MODEL 92 2.5 PRIMARY INTERVIEWS WITH KEY OPINION LEADERS 95 2.6 MULTIVARIATE MODELLING 96 2.7 PRODUCT TYPE SEGMENT LIFELINE CURVE 96 2.8 MARKET END USER COVERAGE GRID 97 2.9 DBMR MARKET POSITION GRID 98 2.10 VENDOR SHARE ANALYSIS 99 2.11 SECONDARY SOURCES 100 2.12 ASSUMPTIONS 100 3 EXECUTIVE SUMMARY 101 4 PREMIUM INSIGHTS 103 4.1 PESTAL ANALYSIS 104 4.2 PORTERS 5 FORCES 105 5 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET: REGULATIONS 106 6 MARKET OVERVIEW 114 6.1 DRIVERS 116 6.1.1 RISING PREVALENCE OF CANCER INCIDENCES 116 6.1.2 RISING TECHNOLOGICAL ADVANCEMENTS 116 6.1.3 INCREASED UNDERSTANDING OF TUMOR MICROENVIRONMENT 117 6.1.4 RISE IN PATIENT AWARENESS AND DEMAND FOR TARGETED TREATMENT 117 6.2 RESTRAINTS 118 6.2.1 INCREASING OCCURRENCE OF IMMUNE-RELATED ADVERSE EVENTS 118 6.2.2 DEVELOPING RESISTANCE TO CANCER TREATMENT 118 6.3 OPPORTUNITIES 119 6.3.1 GROWING TREND TOWARDS COMBINATION THERAPIES 119 6.3.2 RISING INTEGRATION OF ARTIFICIAL INTELLIGENCE AND DIGITAL HEALTH TOOLS 119 6.3.3 DEVELOPMENT OF NEXT-GENERATION IMMUNOTHERAPIES 120 6.4 CHALLENGES 121 6.4.1 LACK OF STANDARDIZATION IN BIOMARKER TESTING 121 6.4.2 COMPLEXITY OF DEVELOPING AND IMPLEMENTING PERSONALIZED MEDICINE 121 7 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY PRODUCT TYPE 122 7.1 OVERVIEW 123 7.2 CHECKPOINT INHIBITORS 126 7.2.1 PROGRAMMED DEATH 1 (PD-1) & PROGRAMMED DEATH LIGAND 1 (PD-L1) 127 7.2.2 CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN-4 (CTLA-4) 127 7.3 MONOCLONAL ANTIBODIES 128 7.3.1 NAKED MONOCLONAL ANTIBODIES 129 7.3.2 CONJUGATED MONOCLONAL ANTIBODIES 129 7.3.3 BISPECIFIC MONOCLONAL ANTIBODIES 129 7.4 VACCINES 130 7.4.1 PROPHYLACTIC VACCINES 131 7.4.2 THERAPEUTIC VACCINES 131 7.5 CELL THERAPIES 131 7.5.1 CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL THERAPY 132 7.5.2 T CELL THERAPY 132 7.6 IMMUNOMODULATORS 132 7.6.1 INTERFERONS 133 7.6.2 INTERLEUKINS 133 7.6.3 GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR 133 7.7 ONCOLYTIC VIRUS 134 8 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY END USER 135 8.1 OVERVIEW 136 8.2 HOSPITALS 139 8.3 ONCOLOGY CLINICS 140 8.4 HOMECARE 140 8.5 OTHERS 141 9 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY DISTRIBUTION CHANNEL 142 9.1 OVERVIEW 143 9.2 DIRECT TENDERS 146 9.3 RETAIL SALES 147 9.4 PHARMACIES 147 9.4.1 HOSPITAL 148 9.4.2 RETAIL 148 9.4.3 ONLINE 148 10 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY FORM 149 10.1 OVERVIEW 150 10.2 INTRAVENOUS (IV) 153 10.3 INTRAMUSCULAR 154 10.4 ORAL 154 11 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY APPLICATION 155 11.1 OVERVIEW 156 11.2 LUNG CANCER 159 11.2.1 CHECKPOINT INHIBITORS 160 11.2.2 MONOCLONAL ANTIBODIES 160 11.2.3 CELL THERAPIES 160 11.2.4 IMMUNOMODULATORS 160 11.3 BREAST CANCER 161 11.3.1 CHECKPOINT INHIBITORS 161 11.3.2 MONOCLONAL ANTIBODIES 161 11.3.3 CELL THERAPIES 162 11.3.4 IMMUNOMODULATORS 162 11.4 MELANOMA 162 11.4.1 CHECKPOINT INHIBITORS 163 11.4.2 MONOCLONAL ANTIBODIES 163 11.4.3 CELL THERAPIES 163 11.4.4 IMMUNOMODULATORS 163 11.4.5 ONCOLYTIC VIRUS 163 11.5 MULTIPLE MYELOMA 164 11.5.1 CHECKPOINT INHIBITORS 164 11.5.2 MONOCLONAL ANTIBODIES 164 11.5.3 CELL THERAPIES 164 11.5.4 IMMUNOMODULATORS 165 11.6 PROSTATE CANCER 165 11.6.1 CHECKPOINT INHIBITORS 165 11.6.2 MONOCLONAL ANTIBODIES 166 11.6.3 CELL THERAPIES 166 11.6.4 IMMUNOMODULATORS 166 11.6.5 VACCINES 166 11.7 OVARIAN CANCER 166 11.7.1 CHECKPOINT INHIBITORS 167 11.7.2 MONOCLONAL ANTIBODIES 167 11.7.3 CELL THERAPIES 167 11.7.4 IMMUNOMODULATORS 167 11.8 CERVICAL CANCER 168 11.8.1 CHECKPOINT INHIBITORS 168 11.8.2 MONOCLONAL ANTIBODIES 168 11.8.3 VACCINES 169 11.8.4 CELL THERAPIES 169 11.8.5 IMMUNOMODULATORS 169 11.9 STOMACH CANCER 169 11.9.1 CHECKPOINT INHIBITORS 170 11.9.2 MONOCLONAL ANTIBODIES 170 11.9.3 CELL THERAPIES 170 11.9.4 IMMUNOMODULATORS 170 11.10 COLORECTAL CANCER 170 11.10.1 CHECKPOINT INHIBITORS 171 11.10.2 MONOCLONAL ANTIBODIES 171 11.10.3 CELL THERAPIES 171 11.10.4 IMMUNOMODULATORS 171 11.11 HEAD AND NECK CANCER 172 11.11.1 CHECKPOINT INHIBITORS 172 11.11.2 MONOCLONAL ANTIBODIES 172 11.11.3 CELL THERAPIES 172 11.11.4 IMMUNOMODULATORS 173 11.12 OTHERS 173 11.12.1 CHECKPOINT INHIBITORS 173 11.12.2 MONOCLONAL ANTIBODIES 173 11.12.3 VACCINES 174 11.12.4 CELL THERAPIES 174 11.12.5 IMMUNOMODULATORS 174 12 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, BY REGION 175 12.1 NORTH AMERICA 177 12.1.1 U.S. 185 12.1.2 CANADA 193 12.1.3 MEXICO 201 13 NORTH AMERICA CANCER IMMUNOTHERAPY MARKET, COMPANY LANDSCAPE 209 13.1 COMPANY SHARE ANALYSIS: NORTH AMERICA 209 14 SWOT ANALYSIS 210 15 COMPANY PROFILES 211 15.1 MERCK & CO., INC. 211 15.1.1 COMPANY SNAPSHOT 211 15.1.2 REVENUE ANALYSIS 211 15.1.3 COMPANY SHARE ANALYSIS 212 15.1.4 PRODUCT PORTFOLIO 212 15.1.5 RECENT DEVELOPMENTS 212 15.2 F. HOFFMANN-LA ROCHE LTD 213 15.2.1 COMPANY SNAPSHOT 213 15.2.2 REVENUE ANALYSIS 213 15.2.3 COMPANY SHARE ANALYSIS 214 15.2.4 PRODUCT PORTFOLIO 214 15.2.5 RECENT DEVELOPMENTS 214 15.3 BRISTOL-MYERS SQUIBB COMPANY 216 15.3.1 COMPANY SNAPSHOT 216 15.3.2 REVENUE ANALYSIS 216 15.3.3 COMPANY SHARE ANALYSIS 217 15.3.4 PRODUCT PORTFOLIO 217 15.3.5 RECENT DEVELOPMENTS 218 15.4 JANSSEN NORTH AMERICA SERVICES, LLC 219 15.4.1 COMPANY SNAPSHOT 219 15.4.2 REVENUE ANALYSIS 219 15.4.3 COMPANY SHARE ANALYSIS 220 15.4.4 PRODUCT PORTFOLIO 220 15.4.5 RECENT DEVELOPMENTS 221 15.5 ASTRAZENECA 222 15.5.1 COMPANY SNAPSHOT 222 15.5.2 REVENUE ANALYSIS 222 15.5.3 COMPANY SHARE ANALYSIS 223 15.5.4 PRODUCT PORTFOLIO 223 15.5.5 RECENT DEVELOPMENTS 224 15.6 ABBVIE INC. 225 15.6.1 COMPANY SNAPSHOT 225 15.6.2 PIPELINE PORTFOLIO 225 15.6.3 RECENT DEVELOPMENTS 225 15.7 AMGEN INC. 226 15.7.1 COMPANY SNAPSHOT 226 15.7.2 REVENUE ANALYSIS 227 15.7.3 PIPELINE PORTFOLIO 227 15.7.4 PRODUCT PORTFOLIO 228 15.7.5 RECENT DEVELOPMENTS 228 15.8 ATARA BIOTHERAPEUTICS, INC. 229 15.8.1 COMPANY SNAPSHOT 229 15.8.2 PIPELINE PORTFOLIO 229 15.8.3 RECENT DEVELOPMENTS 229 15.9 BAYER AG 230 15.9.1 COMPANY SNAPSHOT 230 15.9.2 PIPELINE PORTFOLIO 230 15.9.3 RECENT DEVELOPMENTS 230 15.10 CELLDEX THERAPEUTICS. 232 15.10.1 COMPANY SNAPSHOT 232 15.10.2 PIPELINE PORTFOLIO 232 15.10.3 RECENT DEVELOPMENTS 232 15.11 CELLECTIS 233 15.11.1 COMPANY SNAPSHOT 233 15.11.2 PIPELINE PORTFOLIO 233 15.11.3 RECENT DEVELOPMENTS 233 15.12 GILEAD SCIENCES, INC. 234 15.12.1 COMPANY SNAPSHOT 234 15.12.2 REVENUE ANALYSIS 234 15.12.3 PRODUCT PORTFOLIO 235 15.12.4 RECENT DEVELOPMENTS 235 15.13 GSK PLC. 236 15.13.1 COMPANY SNAPSHOT 236 15.13.2 REVENUE ANALYSIS 236 15.13.3 PRODUCT PORTFOLIO 237 15.13.4 RECENT DEVELOPMENTS 237 15.14 INCYTE. 238 15.14.1 COMPANY SNAPSHOT 238 15.14.2 REVENUE ANALYSIS 238 15.14.3 PRODUCT PORTFOLIO 239 15.14.4 RECENT DEVELOPMENTS 239 15.15 LILLY. 240 15.15.1 COMPANY SNAPSHOT 240 15.15.2 REVENUE ANALYSIS 241 15.15.3 PRODUCT PORTFOLIO 241 15.15.4 RECENT DEVELOPMENTS 242 15.16 NOVARTIS AG 243 15.16.1 COMPANY SNAPSHOT 243 15.16.2 REVENUE ANALYSIS 243 15.16.3 PIPELINE PORTFOLIO 244 15.16.4 PRODUCT PORTFOLIO 244 15.16.5 RECENT DEVELOPMENTS 244 15.17 PFIZER INC. 245 15.17.1 COMPANY SNAPSHOT 245 15.17.2 REVENUE ANALYSIS 245 15.17.3 PRODUCT PORTFOLIO 246 15.17.4 RECENT DEVELOPMENTS 246 16 QUESTIONNAIRE 247 17 RELATED REPORTS 251
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