欧州がん免疫療法市場-2033年までの産業動向と予測Europe Cancer Immunotherapy Market - Industry Trends and Forecast to 2033 欧州のがん免疫療法市場は、2023年の189億2,143万米ドルから2031年には495億1,288万米ドルに達し、2024年から2031年の予測期間中に13.7%のCAGRで成長すると予測されている。 市場セグメンテーション 欧州がん免... もっと見る
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サマリー欧州のがん免疫療法市場は、2023年の189億2,143万米ドルから2031年には495億1,288万米ドルに達し、2024年から2031年の予測期間中に13.7%のCAGRで成長すると予測されている。市場セグメンテーション 欧州がん免疫療法市場:製品タイプ別(チェックポイント阻害剤、モノクローナル抗体、ワクチン、細胞療法、免疫調節剤、がん溶解性ウイルス)、用途別(肺がん、乳がん、メラノーマ、骨髄腫、前立腺がん、卵巣がん、子宮頸がん、胃がん、大腸がん、頭頸部がん、その他)、エンドユーザー(病院、オンコロジークリニック、在宅医療、その他)、剤形(静脈内投与、筋肉内投与、経口投与)、流通チャネル(直接販売、小売販売、薬局)、国(ドイツ、フランス、U.K.,イタリア, ロシア, スペイン, トルコ, ベルギー, オランダ, スイス, デンマーク, その他欧州) - 産業動向と2031年までの予測 欧州がん免疫療法市場ダイナミクスの概要 推進要因 - がん罹患率の上昇 抑制要因 - 免疫関連の有害事象の増加 機会 - 併用療法への傾向の高まり 市場プレイヤー 欧州のがん免疫療法市場で事業を展開する主な市場参入企業は以下の通りである: - メルク社 - ホフマン・ラ・ロシュ社 - ブリストル・マイヤーズ スクイブ社 - ヤンセンファーマ - アストラゼネカ - ギリアド・サイエンシズ - イーライリリー・アンド・カンパニー - アムジェン社 - ノバルティスAG - GSK - ファイザー - インサイト 目次TABLE OF CONTENTS1 INTRODUCTION 83 1.1 OBJECTIVES OF THE STUDY 83 1.2 MARKET DEFINITION 83 1.3 OVERVIEW OF THE EUROPE CANCER IMMUNOTHERAPY MARKET 83 1.4 CURRENCY AND PRICING 85 1.5 LIMITATIONS 85 1.6 MARKETS COVERED 85 2 MARKET SEGMENTATION 89 2.1 MARKETS COVERED 89 2.2 GEOGRAPHICAL SCOPE 90 2.3 YEARS CONSIDERED FOR THE STUDY 91 2.4 DBMR TRIPOD DATA VALIDATION MODEL 92 2.5 PRIMARY INTERVIEWS WITH KEY OPINION LEADERS 95 2.6 MULTIVARIATE MODELLING 96 2.7 PRODUCT TYPE SEGMENT LIFELINE CURVE 96 2.8 MARKET END USER COVERAGE GRID 97 2.9 DBMR MARKET POSITION GRID 98 2.10 VENDOR SHARE ANALYSIS 99 2.11 SECONDARY SOURCES 100 2.12 ASSUMPTIONS 100 3 EXECUTIVE SUMMARY 101 4 PREMIUM INSIGHTS 103 4.1 PESTAL ANALYSIS 104 4.2 PORTERS 5 FORCES 105 5 EUROPE CANCER IMMUNOTHERAPY MARKET: REGULATIONS 106 6 MARKET OVERVIEW 114 6.1 DRIVERS 116 6.1.1 RISING PREVALENCE OF CANCER INCIDENCES 116 6.1.2 RISING TECHNOLOGICAL ADVANCEMENTS 116 6.1.3 INCREASED UNDERSTANDING OF TUMOR MICROENVIRONMENT 117 6.1.4 RISE IN PATIENT AWARENESS AND DEMAND FOR TARGETED TREATMENT 117 6.2 RESTRAINTS 118 6.2.1 INCREASING OCCURRENCE OF IMMUNE-RELATED ADVERSE EVENTS 118 6.2.2 DEVELOPING RESISTANCE TO CANCER TREATMENT 118 6.3 OPPORTUNITIES 119 6.3.1 GROWING TREND TOWARDS COMBINATION THERAPIES 119 6.3.2 RISING INTEGRATION OF ARTIFICIAL INTELLIGENCE AND DIGITAL HEALTH TOOLS 119 6.3.3 DEVELOPMENT OF NEXT-GENERATION IMMUNOTHERAPIES 120 6.4 CHALLENGES 121 6.4.1 LACK OF STANDARDIZATION IN BIOMARKER TESTING 121 6.4.2 COMPLEXITY OF DEVELOPING AND IMPLEMENTING PERSONALIZED MEDICINE 121 7 EUROPE CANCER IMMUNOTHERAPY MARKET , BY PRODUCT TYPE 122 7.1 OVERVIEW 123 7.2 CHECKPOINT INHIBITORS 126 7.2.1 PROGRAMMED DEATH 1 (PD-1) & PROGRAMMED DEATH LIGAND 1 (PD-L1) 127 7.2.2 CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN-4 (CTLA-4) 127 7.3 MONOCLONAL ANTIBODIES 128 7.3.1 NAKED MONOCLONAL ANTIBODIES 129 7.3.2 CONJUGATED MONOCLONAL ANTIBODIES 129 7.3.3 BISPECIFIC MONOCLONAL ANTIBODIES 129 7.4 VACCINES 130 7.4.1 PROPHYLACTIC VACCINES 131 7.4.2 THERAPEUTIC VACCINES 131 7.5 CELL THERAPIES 131 7.5.1 CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL THERAPY 132 7.5.2 T CELL THERAPY 132 7.6 IMMUNOMODULATORS 132 7.6.1 INTERFERONS 133 7.6.2 INTERLEUKINS 133 7.6.3 GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR 133 7.7 ONCOLYTIC VIRUS 134 8 EUROPE CANCER IMMUNOTHERAPY MARKET , BY END USER 135 8.1 OVERVIEW 136 8.2 HOSPITALS 139 8.3 ONCOLOGY CLINICS 140 8.4 HOMECARE 140 8.5 OTHERS 141 9 EUROPE CANCER IMMUNOTHERAPY MARKET, BY DISTRIBUTION CHANNEL 142 9.1 OVERVIEW 143 9.2 DIRECT TENDERS 146 9.3 RETAIL SALES 147 9.4 PHARMACIES 147 9.4.1 HOSPITAL 148 9.4.2 RETAIL 148 9.4.3 ONLINE 148 10 EUROPE CANCER IMMUNOTHERAPY MARKET, BY FORM 149 10.1 OVERVIEW 150 10.2 INTRAVENOUS (IV) 153 10.3 INTRAMUSCULAR 154 10.4 ORAL 154 11 EUROPE CANCER IMMUNOTHERAPY MARKET, BY APPLICATION 155 11.1 OVERVIEW 156 11.2 LUNG CANCER 159 11.2.1 CHECKPOINT INHIBITORS 160 11.2.2 MONOCLONAL ANTIBODIES 160 11.2.3 CELL THERAPIES 160 11.2.4 IMMUNOMODULATORS 160 11.3 BREAST CANCER 161 11.3.1 CHECKPOINT INHIBITORS 161 11.3.2 MONOCLONAL ANTIBODIES 161 11.3.3 CELL THERAPIES 162 11.3.4 IMMUNOMODULATORS 162 11.4 MELANOMA 162 11.4.1 CHECKPOINT INHIBITORS 163 11.4.2 MONOCLONAL ANTIBODIES 163 11.4.3 CELL THERAPIES 163 11.4.4 IMMUNOMODULATORS 163 11.4.5 ONCOLYTIC VIRUS 163 11.5 MULTIPLE MYELOMA 164 11.5.1 CHECKPOINT INHIBITORS 164 11.5.2 MONOCLONAL ANTIBODIES 164 11.5.3 CELL THERAPIES 164 11.5.4 IMMUNOMODULATORS 165 11.6 PROSTATE CANCER 165 11.6.1 CHECKPOINT INHIBITORS 165 11.6.2 MONOCLONAL ANTIBODIES 166 11.6.3 CELL THERAPIES 166 11.6.4 IMMUNOMODULATORS 166 11.6.5 VACCINES 166 11.7 OVARIAN CANCER 166 11.7.1 CHECKPOINT INHIBITORS 167 11.7.2 MONOCLONAL ANTIBODIES 167 11.7.3 CELL THERAPIES 167 11.7.4 IMMUNOMODULATORS 167 11.8 CERVICAL CANCER 168 11.8.1 CHECKPOINT INHIBITORS 168 11.8.2 MONOCLONAL ANTIBODIES 168 11.8.3 VACCINES 169 11.8.4 CELL THERAPIES 169 11.8.5 IMMUNOMODULATORS 169 11.9 STOMACH CANCER 169 11.9.1 CHECKPOINT INHIBITORS 170 11.9.2 MONOCLONAL ANTIBODIES 170 11.9.3 CELL THERAPIES 170 11.9.4 IMMUNOMODULATORS 170 11.10 COLORECTAL CANCER 170 11.10.1 CHECKPOINT INHIBITORS 171 11.10.2 MONOCLONAL ANTIBODIES 171 11.10.3 CELL THERAPIES 171 11.10.4 IMMUNOMODULATORS 171 11.11 HEAD AND NECK CANCER 172 11.11.1 CHECKPOINT INHIBITORS 172 11.11.2 MONOCLONAL ANTIBODIES 172 11.11.3 CELL THERAPIES 172 11.11.4 IMMUNOMODULATORS 173 11.12 OTHERS 173 11.12.1 CHECKPOINT INHIBITORS 173 11.12.2 MONOCLONAL ANTIBODIES 173 11.12.3 VACCINES 174 11.12.4 CELL THERAPIES 174 11.12.5 IMMUNOMODULATORS 174 12 EUROPE CANCER IMMUNOTHERAPY MARKET, BY REGION 175 12.1 EUROPE 177 12.1.1 GERMANY 185 12.1.2 FRANCE 193 12.1.3 ITALY 201 12.1.4 SPAIN 209 12.1.5 U.K. 217 12.1.6 SWITZERLAND 225 12.1.7 NETHERLANDS 233 12.1.8 RUSSIA 241 12.1.9 TURKEY 249 12.1.10 POLAND 257 12.1.11 HUNGARY 265 12.1.12 LITHUANIA 273 12.1.13 AUSTRIA 281 12.1.14 IRELAND 289 12.1.15 NORWAY 297 12.1.16 REST OF EUROPE 305 13 EUROPE CANCER IMMUNOTHERAPY MARKET, COMPANY LANDSCAPE 306 13.1 COMPANY SHARE ANALYSIS: EUROPE 14 SWOT ANALYSIS 307 15 COMPANY PROFILES 308 15.1 MERCK & CO., INC. 308 15.1.1 COMPANY SNAPSHOT 308 15.1.2 REVENUE ANALYSIS 308 15.1.3 COMPANY SHARE ANALYSIS 309 15.1.4 PRODUCT PORTFOLIO 309 15.1.5 RECENT DEVELOPMENTS 309 15.2 F. HOFFMANN-LA ROCHE LTD 310 15.2.1 COMPANY SNAPSHOT 310 15.2.2 REVENUE ANALYSIS 310 15.2.3 COMPANY SHARE ANALYSIS 311 15.2.4 PRODUCT PORTFOLIO 311 15.2.5 RECENT DEVELOPMENTS 311 15.3 BRISTOL-MYERS SQUIBB COMPANY 313 15.3.1 COMPANY SNAPSHOT 313 15.3.2 REVENUE ANALYSIS 313 15.3.3 COMPANY SHARE ANALYSIS 314 15.3.4 PRODUCT PORTFOLIO 314 15.3.5 RECENT DEVELOPMENTS 315 15.4 JANSSEN EUROPE SERVICES, LLC 316 15.4.1 COMPANY SNAPSHOT 316 15.4.2 REVENUE ANALYSIS 316 15.4.3 COMPANY SHARE ANALYSIS 317 15.4.4 PRODUCT PORTFOLIO 317 15.4.5 RECENT DEVELOPMENTS 318 15.5 ASTRAZENECA 319 15.5.1 COMPANY SNAPSHOT 319 15.5.2 REVENUE ANALYSIS 319 15.5.3 COMPANY SHARE ANALYSIS 320 15.5.4 PRODUCT PORTFOLIO 320 15.5.5 RECENT DEVELOPMENTS 321 15.6 ABBVIE INC. 322 15.6.1 COMPANY SNAPSHOT 322 15.6.2 PIPELINE PORTFOLIO 322 15.6.3 RECENT DEVELOPMENTS 322 15.7 AMGEN INC. 323 15.7.1 COMPANY SNAPSHOT 323 15.7.2 REVENUE ANALYSIS 324 15.7.3 PIPELINE PORTFOLIO 324 15.7.4 PRODUCT PORTFOLIO 325 15.7.5 RECENT DEVELOPMENTS 325 15.8 ATARA BIOTHERAPEUTICS, INC. 326 15.8.1 COMPANY SNAPSHOT 326 15.8.2 PIPELINE PORTFOLIO 326 15.8.3 RECENT DEVELOPMENTS 326 15.9 BAYER AG 327 15.9.1 COMPANY SNAPSHOT 327 15.9.2 PIPELINE PORTFOLIO 327 15.9.3 RECENT DEVELOPMENTS 327 15.10 CELLDEX THERAPEUTICS. 329 15.10.1 COMPANY SNAPSHOT 329 15.10.2 PIPELINE PORTFOLIO 329 15.10.3 RECENT DEVELOPMENTS 329 15.11 CELLECTIS 330 15.11.1 COMPANY SNAPSHOT 330 15.11.2 PIPELINE PORTFOLIO 330 15.11.3 RECENT DEVELOPMENTS 330 15.12 GILEAD SCIENCES, INC. 331 15.12.1 COMPANY SNAPSHOT 331 15.12.2 REVENUE ANALYSIS 331 15.12.3 PRODUCT PORTFOLIO 332 15.12.4 RECENT DEVELOPMENTS 332 15.13 GSK PLC. 333 15.13.1 COMPANY SNAPSHOT 333 15.13.2 REVENUE ANALYSIS 333 15.13.3 PRODUCT PORTFOLIO 334 15.13.4 RECENT DEVELOPMENTS 334 15.14 INCYTE. 335 15.14.1 COMPANY SNAPSHOT 335 15.14.2 REVENUE ANALYSIS 335 15.14.3 PRODUCT PORTFOLIO 336 15.14.4 RECENT DEVELOPMENTS 336 15.15 LILLY. 337 15.15.1 COMPANY SNAPSHOT 337 15.15.2 REVENUE ANALYSIS 338 15.15.3 PRODUCT PORTFOLIO 338 15.15.4 RECENT DEVELOPMENTS 339 15.16 NOVARTIS AG 340 15.16.1 COMPANY SNAPSHOT 340 15.16.2 REVENUE ANALYSIS 340 15.16.3 PIPELINE PORTFOLIO 341 15.16.4 PRODUCT PORTFOLIO 341 15.16.5 RECENT DEVELOPMENTS 341 15.17 PFIZER INC. 342 15.17.1 COMPANY SNAPSHOT 342 15.17.2 REVENUE ANALYSIS 342 15.17.3 PRODUCT PORTFOLIO 343 15.17.4 RECENT DEVELOPMENTS 343 16 QUESTIONNAIRE 344 17 RELATED REPORTS 348
SummaryThe Europe cancer immunotherapy market is expected to reach USD 49,512.88 million by 2031 from USD 18,921.43 million in 2023, growing at a CAGR of 13.7% during the forecast period of 2024 to 2031. Table of ContentsTABLE OF CONTENTS1 INTRODUCTION 83 1.1 OBJECTIVES OF THE STUDY 83 1.2 MARKET DEFINITION 83 1.3 OVERVIEW OF THE EUROPE CANCER IMMUNOTHERAPY MARKET 83 1.4 CURRENCY AND PRICING 85 1.5 LIMITATIONS 85 1.6 MARKETS COVERED 85 2 MARKET SEGMENTATION 89 2.1 MARKETS COVERED 89 2.2 GEOGRAPHICAL SCOPE 90 2.3 YEARS CONSIDERED FOR THE STUDY 91 2.4 DBMR TRIPOD DATA VALIDATION MODEL 92 2.5 PRIMARY INTERVIEWS WITH KEY OPINION LEADERS 95 2.6 MULTIVARIATE MODELLING 96 2.7 PRODUCT TYPE SEGMENT LIFELINE CURVE 96 2.8 MARKET END USER COVERAGE GRID 97 2.9 DBMR MARKET POSITION GRID 98 2.10 VENDOR SHARE ANALYSIS 99 2.11 SECONDARY SOURCES 100 2.12 ASSUMPTIONS 100 3 EXECUTIVE SUMMARY 101 4 PREMIUM INSIGHTS 103 4.1 PESTAL ANALYSIS 104 4.2 PORTERS 5 FORCES 105 5 EUROPE CANCER IMMUNOTHERAPY MARKET: REGULATIONS 106 6 MARKET OVERVIEW 114 6.1 DRIVERS 116 6.1.1 RISING PREVALENCE OF CANCER INCIDENCES 116 6.1.2 RISING TECHNOLOGICAL ADVANCEMENTS 116 6.1.3 INCREASED UNDERSTANDING OF TUMOR MICROENVIRONMENT 117 6.1.4 RISE IN PATIENT AWARENESS AND DEMAND FOR TARGETED TREATMENT 117 6.2 RESTRAINTS 118 6.2.1 INCREASING OCCURRENCE OF IMMUNE-RELATED ADVERSE EVENTS 118 6.2.2 DEVELOPING RESISTANCE TO CANCER TREATMENT 118 6.3 OPPORTUNITIES 119 6.3.1 GROWING TREND TOWARDS COMBINATION THERAPIES 119 6.3.2 RISING INTEGRATION OF ARTIFICIAL INTELLIGENCE AND DIGITAL HEALTH TOOLS 119 6.3.3 DEVELOPMENT OF NEXT-GENERATION IMMUNOTHERAPIES 120 6.4 CHALLENGES 121 6.4.1 LACK OF STANDARDIZATION IN BIOMARKER TESTING 121 6.4.2 COMPLEXITY OF DEVELOPING AND IMPLEMENTING PERSONALIZED MEDICINE 121 7 EUROPE CANCER IMMUNOTHERAPY MARKET , BY PRODUCT TYPE 122 7.1 OVERVIEW 123 7.2 CHECKPOINT INHIBITORS 126 7.2.1 PROGRAMMED DEATH 1 (PD-1) & PROGRAMMED DEATH LIGAND 1 (PD-L1) 127 7.2.2 CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN-4 (CTLA-4) 127 7.3 MONOCLONAL ANTIBODIES 128 7.3.1 NAKED MONOCLONAL ANTIBODIES 129 7.3.2 CONJUGATED MONOCLONAL ANTIBODIES 129 7.3.3 BISPECIFIC MONOCLONAL ANTIBODIES 129 7.4 VACCINES 130 7.4.1 PROPHYLACTIC VACCINES 131 7.4.2 THERAPEUTIC VACCINES 131 7.5 CELL THERAPIES 131 7.5.1 CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL THERAPY 132 7.5.2 T CELL THERAPY 132 7.6 IMMUNOMODULATORS 132 7.6.1 INTERFERONS 133 7.6.2 INTERLEUKINS 133 7.6.3 GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR 133 7.7 ONCOLYTIC VIRUS 134 8 EUROPE CANCER IMMUNOTHERAPY MARKET , BY END USER 135 8.1 OVERVIEW 136 8.2 HOSPITALS 139 8.3 ONCOLOGY CLINICS 140 8.4 HOMECARE 140 8.5 OTHERS 141 9 EUROPE CANCER IMMUNOTHERAPY MARKET, BY DISTRIBUTION CHANNEL 142 9.1 OVERVIEW 143 9.2 DIRECT TENDERS 146 9.3 RETAIL SALES 147 9.4 PHARMACIES 147 9.4.1 HOSPITAL 148 9.4.2 RETAIL 148 9.4.3 ONLINE 148 10 EUROPE CANCER IMMUNOTHERAPY MARKET, BY FORM 149 10.1 OVERVIEW 150 10.2 INTRAVENOUS (IV) 153 10.3 INTRAMUSCULAR 154 10.4 ORAL 154 11 EUROPE CANCER IMMUNOTHERAPY MARKET, BY APPLICATION 155 11.1 OVERVIEW 156 11.2 LUNG CANCER 159 11.2.1 CHECKPOINT INHIBITORS 160 11.2.2 MONOCLONAL ANTIBODIES 160 11.2.3 CELL THERAPIES 160 11.2.4 IMMUNOMODULATORS 160 11.3 BREAST CANCER 161 11.3.1 CHECKPOINT INHIBITORS 161 11.3.2 MONOCLONAL ANTIBODIES 161 11.3.3 CELL THERAPIES 162 11.3.4 IMMUNOMODULATORS 162 11.4 MELANOMA 162 11.4.1 CHECKPOINT INHIBITORS 163 11.4.2 MONOCLONAL ANTIBODIES 163 11.4.3 CELL THERAPIES 163 11.4.4 IMMUNOMODULATORS 163 11.4.5 ONCOLYTIC VIRUS 163 11.5 MULTIPLE MYELOMA 164 11.5.1 CHECKPOINT INHIBITORS 164 11.5.2 MONOCLONAL ANTIBODIES 164 11.5.3 CELL THERAPIES 164 11.5.4 IMMUNOMODULATORS 165 11.6 PROSTATE CANCER 165 11.6.1 CHECKPOINT INHIBITORS 165 11.6.2 MONOCLONAL ANTIBODIES 166 11.6.3 CELL THERAPIES 166 11.6.4 IMMUNOMODULATORS 166 11.6.5 VACCINES 166 11.7 OVARIAN CANCER 166 11.7.1 CHECKPOINT INHIBITORS 167 11.7.2 MONOCLONAL ANTIBODIES 167 11.7.3 CELL THERAPIES 167 11.7.4 IMMUNOMODULATORS 167 11.8 CERVICAL CANCER 168 11.8.1 CHECKPOINT INHIBITORS 168 11.8.2 MONOCLONAL ANTIBODIES 168 11.8.3 VACCINES 169 11.8.4 CELL THERAPIES 169 11.8.5 IMMUNOMODULATORS 169 11.9 STOMACH CANCER 169 11.9.1 CHECKPOINT INHIBITORS 170 11.9.2 MONOCLONAL ANTIBODIES 170 11.9.3 CELL THERAPIES 170 11.9.4 IMMUNOMODULATORS 170 11.10 COLORECTAL CANCER 170 11.10.1 CHECKPOINT INHIBITORS 171 11.10.2 MONOCLONAL ANTIBODIES 171 11.10.3 CELL THERAPIES 171 11.10.4 IMMUNOMODULATORS 171 11.11 HEAD AND NECK CANCER 172 11.11.1 CHECKPOINT INHIBITORS 172 11.11.2 MONOCLONAL ANTIBODIES 172 11.11.3 CELL THERAPIES 172 11.11.4 IMMUNOMODULATORS 173 11.12 OTHERS 173 11.12.1 CHECKPOINT INHIBITORS 173 11.12.2 MONOCLONAL ANTIBODIES 173 11.12.3 VACCINES 174 11.12.4 CELL THERAPIES 174 11.12.5 IMMUNOMODULATORS 174 12 EUROPE CANCER IMMUNOTHERAPY MARKET, BY REGION 175 12.1 EUROPE 177 12.1.1 GERMANY 185 12.1.2 FRANCE 193 12.1.3 ITALY 201 12.1.4 SPAIN 209 12.1.5 U.K. 217 12.1.6 SWITZERLAND 225 12.1.7 NETHERLANDS 233 12.1.8 RUSSIA 241 12.1.9 TURKEY 249 12.1.10 POLAND 257 12.1.11 HUNGARY 265 12.1.12 LITHUANIA 273 12.1.13 AUSTRIA 281 12.1.14 IRELAND 289 12.1.15 NORWAY 297 12.1.16 REST OF EUROPE 305 13 EUROPE CANCER IMMUNOTHERAPY MARKET, COMPANY LANDSCAPE 306 13.1 COMPANY SHARE ANALYSIS: EUROPE 14 SWOT ANALYSIS 307 15 COMPANY PROFILES 308 15.1 MERCK & CO., INC. 308 15.1.1 COMPANY SNAPSHOT 308 15.1.2 REVENUE ANALYSIS 308 15.1.3 COMPANY SHARE ANALYSIS 309 15.1.4 PRODUCT PORTFOLIO 309 15.1.5 RECENT DEVELOPMENTS 309 15.2 F. HOFFMANN-LA ROCHE LTD 310 15.2.1 COMPANY SNAPSHOT 310 15.2.2 REVENUE ANALYSIS 310 15.2.3 COMPANY SHARE ANALYSIS 311 15.2.4 PRODUCT PORTFOLIO 311 15.2.5 RECENT DEVELOPMENTS 311 15.3 BRISTOL-MYERS SQUIBB COMPANY 313 15.3.1 COMPANY SNAPSHOT 313 15.3.2 REVENUE ANALYSIS 313 15.3.3 COMPANY SHARE ANALYSIS 314 15.3.4 PRODUCT PORTFOLIO 314 15.3.5 RECENT DEVELOPMENTS 315 15.4 JANSSEN EUROPE SERVICES, LLC 316 15.4.1 COMPANY SNAPSHOT 316 15.4.2 REVENUE ANALYSIS 316 15.4.3 COMPANY SHARE ANALYSIS 317 15.4.4 PRODUCT PORTFOLIO 317 15.4.5 RECENT DEVELOPMENTS 318 15.5 ASTRAZENECA 319 15.5.1 COMPANY SNAPSHOT 319 15.5.2 REVENUE ANALYSIS 319 15.5.3 COMPANY SHARE ANALYSIS 320 15.5.4 PRODUCT PORTFOLIO 320 15.5.5 RECENT DEVELOPMENTS 321 15.6 ABBVIE INC. 322 15.6.1 COMPANY SNAPSHOT 322 15.6.2 PIPELINE PORTFOLIO 322 15.6.3 RECENT DEVELOPMENTS 322 15.7 AMGEN INC. 323 15.7.1 COMPANY SNAPSHOT 323 15.7.2 REVENUE ANALYSIS 324 15.7.3 PIPELINE PORTFOLIO 324 15.7.4 PRODUCT PORTFOLIO 325 15.7.5 RECENT DEVELOPMENTS 325 15.8 ATARA BIOTHERAPEUTICS, INC. 326 15.8.1 COMPANY SNAPSHOT 326 15.8.2 PIPELINE PORTFOLIO 326 15.8.3 RECENT DEVELOPMENTS 326 15.9 BAYER AG 327 15.9.1 COMPANY SNAPSHOT 327 15.9.2 PIPELINE PORTFOLIO 327 15.9.3 RECENT DEVELOPMENTS 327 15.10 CELLDEX THERAPEUTICS. 329 15.10.1 COMPANY SNAPSHOT 329 15.10.2 PIPELINE PORTFOLIO 329 15.10.3 RECENT DEVELOPMENTS 329 15.11 CELLECTIS 330 15.11.1 COMPANY SNAPSHOT 330 15.11.2 PIPELINE PORTFOLIO 330 15.11.3 RECENT DEVELOPMENTS 330 15.12 GILEAD SCIENCES, INC. 331 15.12.1 COMPANY SNAPSHOT 331 15.12.2 REVENUE ANALYSIS 331 15.12.3 PRODUCT PORTFOLIO 332 15.12.4 RECENT DEVELOPMENTS 332 15.13 GSK PLC. 333 15.13.1 COMPANY SNAPSHOT 333 15.13.2 REVENUE ANALYSIS 333 15.13.3 PRODUCT PORTFOLIO 334 15.13.4 RECENT DEVELOPMENTS 334 15.14 INCYTE. 335 15.14.1 COMPANY SNAPSHOT 335 15.14.2 REVENUE ANALYSIS 335 15.14.3 PRODUCT PORTFOLIO 336 15.14.4 RECENT DEVELOPMENTS 336 15.15 LILLY. 337 15.15.1 COMPANY SNAPSHOT 337 15.15.2 REVENUE ANALYSIS 338 15.15.3 PRODUCT PORTFOLIO 338 15.15.4 RECENT DEVELOPMENTS 339 15.16 NOVARTIS AG 340 15.16.1 COMPANY SNAPSHOT 340 15.16.2 REVENUE ANALYSIS 340 15.16.3 PIPELINE PORTFOLIO 341 15.16.4 PRODUCT PORTFOLIO 341 15.16.5 RECENT DEVELOPMENTS 341 15.17 PFIZER INC. 342 15.17.1 COMPANY SNAPSHOT 342 15.17.2 REVENUE ANALYSIS 342 15.17.3 PRODUCT PORTFOLIO 343 15.17.4 RECENT DEVELOPMENTS 343 16 QUESTIONNAIRE 344 17 RELATED REPORTS 348
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