Summary

Epigenetics Market Size
The global epigenetics market size was valued at $2.14 billion in 2024 and is projected to reach $6.08 billion by 2030, growing at a CAGR of 19.0% during the forecast period.

Epigenetics Market Overview
Epigenetics is the study of changes in gene expression or cellular phenotype that do not involve alterations in the underlying DNA sequence. This field explores how environmental factors, such as diet, stress, and exposure to toxins, can influence the way genes are turned on or off, without changing the genetic code itself. These changes are often mediated by chemical modifications to DNA or histone proteins, which can affect how tightly or loosely DNA is wound around histones, thereby controlling access to the genetic information. Epigenetic modifications can be heritable, passed down from one generation to the next, yet they are also reversible, allowing organisms to adapt to changing environments. This dynamic interplay between genetics and environment helps explain variations in traits and diseases that cannot be attributed solely to genetic mutations.

Epigenetics Market Dynamics
• The epigenetics market is expected to witness significant growth in the future due to increasing prevalence of cancer and chronic diseases, advances in epigenetic research and technology, and growing investment in biotechnology and pharmaceutical sectors.
• Additionally, the rising demand for personalized medicine, expanding applications of epigenetics in drug discovery and development, and increasing collaboration between academic institutions and biotech companies are the prominent factors driving the growth of the market.
• However, the high cost of epigenetic research and therapies, limited awareness and understanding of epigenetics, and ethical and regulatory challenges are restraining the market growth.
• On the contrary, the expansion into emerging markets, advances in next-generation sequencing and bioinformatics tools, and growing focus on early detection and prevention of diseases through epigenetic biomarkers are creating opportunities for market growth.

By End User, the Pharmaceutical and Biotechnology Segment Constitutes Immense Share with Epigenetics Market
The pharmaceutical and biotechnology segment holds a significant share within the epigenetics market owing to its transformational potential for understanding and treating complicated disorders. Epigenetics, which studies heritable changes in gene expression without changing the underlying DNA sequence, provides fundamental insights into the processes of diseases such as cancer, neurological disorders, and autoimmune ailments. This improved understanding allows for the creation of novel therapies that can precisely target epigenetic changes, resulting in more effective and tailored treatments. Additionally, the advancements in epigenetic research tools and technologies have increased drug discovery and development processes, making it a crucial area of focus for pharmaceutical and biotechnology companies. The growing recognition of the role of epigenetic mechanisms in disease etiology and progression, coupled with the promise of innovative therapeutic interventions, underscores the significant demand for epigenetics in these industries.

By Geography, North America is Projected to Show Strong Presence in the Epigenetics Market
North America is anticipated to show a robust presence during the forecast period due to the substantial investments in R&D, a strong presence of key market players, and a highly developed healthcare infrastructure. In the United States, the epigenetics industry benefits from significant federal funding and private investments. Canada's epigenetics market, though smaller than the US, is experiencing rapid growth due to increased research activities and government support. Organizations such as the Canadian Institutes of Health Research (CIHR) provide substantial funding for genetic and epigenetic studies. Canadian researchers actively participate in international collaborations, contributing significantly to advancements in the field. The Canadian healthcare system, known for its focus on accessibility and quality, increasingly incorporates epigenetic insights into clinical practice, particularly in oncology and chronic disease management. The biotech sector in Canada is also expanding, with numerous startups and established companies investing in epigenetic research and development.
• According to the US Department of Health and Human Services, over 129 million people in the US suffer from at least one chronic disease. Additionally, 42% of Americans have two or more chronic conditions, while 12% have at least five.

Key Target Audience:
• Researchers and Scientists
• Pharmaceutical Companies
• Academic Institutions
• Biotechnology Companies

List of the Key Players Profiled in the Report Includes:
• Thermo Fisher Scientific Inc.
• Illumina, Inc.
• PacBio
• Abcam plc
• Merck KGaA
• Active Motif, Inc.
• Bio-Rad Laboratories Inc.
• Promega Corporation
• Zymo Research Corporation
• Diagenode SA
• F. Hoffmann-La Roche Ltd
• QIAGEN

Recent Developments:
• In March 2024, PacBio introduced the PureTarget repeat expansion panel, a groundbreaking solution for the comprehensive analysis of 20 genes linked to serious neurological disorders, including those with challenging tandem repeat expansions. This new long-read workflow streamlines the process by minimizing the need for iterative analysis using legacy technology, significantly reducing the time required to identify disease-causing variants and associated methylation signatures.

Market Segmentation:
The research report includes in-depth coverage of the industry analysis with size, share, and forecast for the below segments:

Market by, Product:
• Enzymes
• Instruments and Accessories
• Reagents and Kits
• Service
• Software

Market by, Method:
• Chromatin Structures
• DNA Methylation
• Histone Acetylation
• Histone Methylation
• Histone Modifications
• Large non-coding RNA
• MicroRNA Modification
• Other Methods

Market by, Technique:
• Mass Spectrometry
• Next-Generation Sequencing (NGS)
• Polymerase Chain Reaction (PCR) & Quantitative Polymerase Chain Reaction (qPCR)
• Sonication
• Other Techniques

Market by, End User:
• Academic and Research Institutions
• Clinical Research
• Contract Research Organizations (CROS)
• Hospitals & Clinics
• Pharmaceutical and Biotechnology Companies
• Other End Users

Market by, Application:
• Oncology
• Non-Oncology

Market by, Geography:
The epigenetics market report also analyzes the major geographic regions and countries of the market. The regions and countries covered in the study include:
• North America (The United States, Canada, Mexico), Market Estimates, Forecast & Opportunity Analysis
• Europe (Germany, France, UK, Italy, Spain, Rest of Europe), Market Estimates, Forecast & Opportunity Analysis
• Asia Pacific (China, Japan, India, South Korea, Australia, New Zealand, Rest of Asia Pacific), Market Estimates, Forecast & Opportunity Analysis
• South America (Brazil, Argentina, Chile, Rest of South America), Market Estimates, Forecast & Opportunity Analysis
• Middle East & Africa (UAE, Saudi Arabia, Qatar, Iran, South Africa, Rest of Middle East & Africa), Market Estimates, Forecast & Opportunity Analysis

Scope of the Report:
The report “Global Epigenetics Market: Industry Analysis, Opportunities and Forecast up to 2030” by Diligence Insights provides a detailed analysis of the present market and future outlook with market estimates and forecasts for all specified segments, encompassing both global and regional perspectives as outlined within the research framework. The study includes historical market data for the years 2022, 2023 and offers revenue estimations for 2024, and project forecasts spanning from 2025 to 2030. It places significant emphasis on the examination of market trends, key industry participants, supply chain developments, technological advancements, pivotal milestones, and prospective strategies. Comprehensive market assessments are carried out across major geographic regions, including North America, Europe, Asia Pacific, South America, and Middle East & Africa. As such, this report constitutes a valuable resource for current industry stakeholders, newcomers to the field, and potential investors.

The study offers an in-depth market analysis, drawing insights from industry experts across the value chain. A special focus has been made on 25 countries, including the United States, Canada, Mexico, the United Kingdom, Germany, Spain, France, Italy, China, Brazil, Saudi Arabia, and South Africa, among others. The market data has been meticulously collected through extensive primary interviews and comprehensive secondary research. Market size determination is rooted in the revenue generated from sales across all the specified segments and sub-segments as defined within the research scope. The market sizing analysis includes both top-down and bottom-up approaches for data validation and accuracy measures.

The report offers insights into the following aspects:
• Analysis of major market trends, factors driving, restraining, threatening, and providing opportunities for the market.
• Analysis of the market structure by identifying various segments and sub-segments of the market.
• Understand the revenue forecast of the market for North America, Europe, Asia-Pacific, South America, and Middle East & Africa.
• Analysis of opportunities by identification of high-growth segments/revenue pockets in the market.
• Understand major player profiles in the market and analyze their business strategies.
• Understand competitive developments such as joint ventures, alliances, mergers and acquisitions, and new product launches in the market.

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Table of Contents

1 Market Introduction
1.1 Market Definition
1.2 Research Scope and Segmentation
1.3 Stakeholders
1.4 List of Abbreviations

2 Executive Summary

3 Research Methodology
3.1 Identification of Data
3.2 Data Analysis
3.3 Verification
3.4 Data Sources
3.5 Assumptions

4 Market Dynamics
4.1 Market Drivers
4.2 Market Restraints
4.3 Market Opportunities
4.4 Market Challenges

5 Porter's Five Force Analysis
5.1 Bargaining Power of Suppliers
5.2 Bargaining Power of Buyers
5.3 Threat of New Entrants
5.4 Threat of Substitutes
5.5 Competitive Rivalry in the Market

6 Global Epigenetics Market by, Product
6.1 Overview
6.2 Enzymes
6.3 Instruments and Accessories
6.4 Reagents and Kits
6.4.1 Bisulfite Conversion Kit
6.4.2 ChIP Sequencing Kit
6.4.3 RNA Sequencing Kit
6.4.4 Whole Genomic Amplification Kit
6.4.5 Other Reagents and Kits
6.5 Service
6.6 Software

7 Global Epigenetics Market by, Method
7.1 Overview
7.2 Chromatin Structures
7.3 DNA Methylation
7.4 Histone Acetylation
7.5 Histone Methylation
7.6 Histone Modifications
7.7 Large non-coding RNA
7.8 MicroRNA Modification
7.9 Other Methods

8 Global Epigenetics Market by, Technique
8.1 Overview
8.2 Mass Spectrometry
8.3 Next-Generation Sequencing (NGS)
8.4 Polymerase Chain Reaction (PCR) & Quantitative Polymerase Chain Reaction (qPCR)
8.5 Sonication
8.6 Other Techniques
8.6.1 Magnetic Separators
8.6.2 Microarrays

9 Global Epigenetics Market by, End User
9.1 Overview
9.2 Academic and Research Institutions
9.3 Clinical Research
9.4 Contract Research Organizations (CROS)
9.5 Hospitals & Clinics
9.6 Pharmaceutical and Biotechnology Companies
9.7 Other End Users

10 Global Epigenetics Market by, Application
10.1 Overview
10.2 Oncology
10.3 Non-Oncology
10.3.1 Autoimmune Diseases
10.3.2 Cardiovascular Diseases
10.3.3 Central Nervous System (CNS)/Pain Diseases
10.3.4 Developmental Biology
10.3.5 Immunology
10.3.6 Metabolic Diseases
10.3.7 Other Applications

11 Global Epigenetics Market by, Geography
11.1 Overview
11.2 North America
11.2.1 US
11.2.2 Canada
11.2.3 Mexico
11.3 Europe
11.3.1 Germany
11.3.2 France
11.3.3 UK
11.3.4 Italy
11.3.5 Spain
11.3.6 Rest of Europe
11.4 Asia Pacific
11.4.1 China
11.4.2 Japan
11.4.3 India
11.4.4 South Korea
11.4.5 Australia
11.4.6 New Zealand
11.4.7 Rest of Asia Pacific
11.5 South America
11.5.1 Brazil
11.5.2 Argentina
11.5.3 Chile
11.5.4 Rest of South America
11.6 Middle East & Africa
11.6.1 UAE
11.6.2 Saudi Arabia
11.6.3 Qatar
11.6.4 Iran
11.6.5 South Africa
11.6.6 Rest of Middle East & Africa

12 Key Developments

13 Company Profiling
13.1 Thermo Fisher Scientific Inc.
13.1.1 Business Overview
13.1.2 Product/Service Offering
13.1.3 Financial Overview
13.1.4 SWOT Analysis
13.1.5 Key Activities
13.2 Illumina, Inc.
13.3 PacBio
13.4 Abcam plc
13.5 Merck KGaA
13.6 Active Motif, Inc.
13.7 Bio-Rad Laboratories Inc.
13.8 Promega Corporation
13.9 Zymo Research Corporation
13.10 Diagenode SA
13.11 F. Hoffmann-La Roche Ltd
13.12 QIAGEN